HOME >> BIOLOGY >> NEWS
Embryonic stem cell therapy shows steady benefits in rebuilding infarcted heart

BETHESDA, MD (August 18, 2004) - Despite improvements in earlier diagnosis and treatment, cardiovascular disease is far and away the leading cause of death in the U.S. and the world.

According to the latest posted statistics, heart disease causes 700,000 deaths in the U.S. each year, with the number of adults diagnosed with heart disease exceeding 23 million, or 11.5% of the adult population.

Previously thought of as concentrated in rich countries, ischemic heart and related cerebrovascular diseases alone caused an estimated 17 million or 23.2% of deaths globally in 2000, WHO reported.

A contributing cause of what some have called a pandemic is that in contrast to many other organs in the body, the heart has only a minimal capability for self-renewal, leaving most current therapies to address symptoms with little hope of rehabilitating the injured heart itself after a heart attack (myocardial infarction).

The regenerative potential of stem cells in relation to the muscle layer of the heart wall (or myocardium) has been recently recognized, but how this might translate into therapeutic uses to repair the heart has been limited.

Mayo Clinic team demonstrates potential for "rebuilding" damaged heart

Using embryonic stem cells, Mayo Clinic researchers transformed these master cell types into fully functional cardiac cells and transplanted them into damaged regions of the myocardium, where the cells integrated into the infarct and showed rapid and robust improvements, which were stable over an extended period post-therapy.

The study, entitled "Stable benefit of embryonic stem cell therapy in myocardial infarction," appears in the August 2004 edition of the American Journal of Physiology-Heart and Circulatory Physiology, one of 14 peer-reviewed journals published by the American Physiological Society.

The investigative team under the direction of Andre Terzic included Denice M. Hodgson, Atta Behf
'"/>


18-Aug-2004


Page: 1 2 3

Related biology news :

1. Embryonic stem cell - based tissue engineering may help repair damaged heart muscle
2. Embryonic skin cells committed at an early age
3. Embryonic pig cell transplants halt rat diabetes
4. Embryonic pathway critical to growth of digestive tract tumors
5. Embryonic hope for damaged spines
6. Embryonic facial development subject to insult or repair longer than expected
7. Embryonic mouse stem cells reduce symptoms in model for Parkinsons disease
8. Statement Of The DFG Concerning "Questions Of Human Embryonic Stem Cells"
9. Molecular Control Mechanism Of Embryonic Development Unraveled
10. First Derivation Of Human Embryonic Stem Cells Reported In Science
11. Hopkins Research Team Cultures Long-Awaited Human Embryonic Stem Cells

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/18/2018)... ... 18, 2018 , ... CP Merritt is a national champion Arabian horse that ... however in 2006, he had a medical setback that caused him to limp at ... from cartilage degeneration in his right rear fetlock. Such an injury could be ...
(Date:12/13/2018)... ... December 12, 2018 , ... Illumina, Kaiser Permanente, ResMed and ... The San Diego-based team-building and cooking events company has hosted an impressive guest ... cooking challenges. , Each group who visits receives a completely customized experience, ...
(Date:12/6/2018)... ... December 06, 2018 , ... Stewart has been ... contract services, throughout his career. During his recent five-year tenure with InSphero he ... established the commercial laboratory operations in Brunswick, Maine. Through these experiences, Stewart has ...
Breaking Biology News(10 mins):
(Date:1/8/2019)... ... ... The American Society of Gene and Cell Therapy’s (ASGCT) first class ... of industry leaders identified by the ASGCT board of directors. In total, the Society ... ASGCT members designing transformative pilot studies in gene and cell therapy as they prepare ...
(Date:1/4/2019)... ... January 02, 2019 , ... ... detect precancer and cancer cells in blood, has been named as a partner ... global biotech company developing cell therapies for cancer treatment, will use CellMax Life’s ...
(Date:12/19/2018)... ... 2018 , ... RURO, Inc., a leading provider of information ... The new release enhances the latest version of Limfinity®, RURO’s software framework, and ... , Validation protocols, and their execution, are critical for software systems scrutinized by ...
(Date:12/14/2018)... ... 2018 , ... NOVA OCULUS PARTNERS, LLC, and its Canadian ... immediately begin a clinical patient trial in Edmonton using their pioneering technology for ... has granted what is called an Investigational Testing Authorization for the trial, while ...
Breaking Biology Technology:
Cached News: