Emerging 'R&D' patterns in genes may reduce evolution's risks

The genetic blueprint at the heart of life may be divided into "research and development" and "production" sections, according to an author of a new study in this week's "Science" that compares genetic material in yeast, roundworms, insects and humans.

The distinction may help shunt the random genetic changes that cause evolution onto areas of the DNA where such changes have a better chance of benefitting the organism (the "R&D" section) and away from areas where they would more likely harm it (the "production" section).

"The great paradox of evolution is that you have many established functions to maintain in an organism, and how can you be conservative about those functions while experimenting to discover new and possibly advantageous gene functions?" says Edward Hedgecock, biology professor at The Johns Hopkins University.

If it is confirmed, the theory could aid researchers in their efforts to analyze genetic information from humans and other species.

With support from the National Institutes of Health, Hedgecock and other researchers conducted an extensive computerized comparison of the sequence of genetic information, known as genomes, found in yeast, the roundworm C. elegans and other nematodes, the fruit fly Drosophila, and humans.

New species arise throughout evolution. Comparing their genomes can therefore provide "snapshots" of the development of DNA at various points in evolutionary history. Since portions of DNA are used as instructions for building proteins, researchers can compare the details of these "snapshots" to get a feel for when life first developed various proteins.

If, for example, a gene for a protein is common to yeast and to animals, Hedgecock explains, then the protein's birth date was before the emergence of multicellular organisms.

Hedgecock and his coauthors focused most of their attention on proteins involved in the creation of

Contact: Michael Purdy
Johns Hopkins University

Page: 1 2 3

Related biology news :

1. International Conference on Emerging Infectious Diseases
2. Emerging frontiers genomics grant for blue-green bacteria
3. Emerging threats to tropical forests
4. Biological Challenges to Humanity: Emerging and Re-emerging Pathogens
5. 2002 International Conference on Emerging Infectious Diseases
6. Emerging trends: Scientific evidence in the courtroom
7. Emerging infectious diseases of wild animals are a threat to biodiversity and human health, according to new report
8. DNA Used To Create Self Assembling Conducting Wire: Breakthrough Will Lead To Next Leap In Emerging Nanoelectronics
9. Molecular Mechanochemistry: An Emerging Discipline At The Nexus Of Biology And Physics
10. Emerging Field Of Industrial Ecology
11. Outcome for acute lymphoblastic leukemia linked to gene expression patterns

Post Your Comments:

(Date:11/16/2015)... Nov 16, 2015  Synaptics Inc. (NASDAQ: ... solutions, today announced expansion of its TDDI product ... touch controller and display driver integration (TDDI) solutions ... These new TDDI products add to the previously-announced ... TD4302 (WQHD resolution), and TD4322 (FHD resolution) solutions. ...
(Date:11/10/2015)... , Nov. 10, 2015  In this ... the basis of product, type, application, disease ... in this report are consumables, services, software. ... are safety biomarkers, efficacy biomarkers, and validation ... report are diagnostics development, drug discovery and ...
(Date:11/2/2015)...  SRI International has been awarded a contract of ... to the National Cancer Institute (NCI) PREVENT Cancer Program ... modern testing and support facilities, and analytical instrumentation to ... studies to evaluate potential cancer prevention drugs. ... Drug Development Program is an NCI-supported pipeline to bring ...
Breaking Biology News(10 mins):
(Date:12/1/2015)... Today the Allen Institute announced the opening of its ... Lake Union neighborhood, the city,s biotechnology hub. Located on ... North, the 270,000 square foot life sciences building is ... the Allen Institute for Cell Science. Paul ... Institute. "We started by building a map of the ...
(Date:12/1/2015)... Dec. 1, 2015 Oxford Finance LLC ("Oxford"), ... life sciences and healthcare services companies, today announced the ... with MDRejuvena, Inc. ("the Company"). Proceeds from the loan ... of the Company,s Rejuvaphyl™ and daily skincare products. ... the MDRejuvena brand of high potency skincare products that ...
(Date:12/1/2015)... (PRWEB) , ... December 01, 2015 , ... ... (AFM) announces Park NX10 SICM Module, an add-on scanning ion conductance microscopy module ... power of SICM to an AFM. , Park SICM benefits virtually all materials ...
(Date:12/1/2015)... Cepheid (Nasdaq: CPHD ) today announced ... Jaffray Healthcare Conference in New York City ... its outlook for the fourth quarter of 2015 and ... longer term business model expectations. John Bishop ... to be the fastest growing company of the major ...
Breaking Biology Technology:
Cached News: