This team will develop and apply experimental and computational methods to understand proteins, protein-protein interactions and the gene regulatory networks that control the production of these proteins in a marine microbe that plays a significant role in earth's carbon cycle.
Cooperative Agreement with the University of Massachusetts, Amherst $8.9 million over 3 years
Analysis of the Genetic Potential and Gene Expression of Microbial Communities Involved in the in situ Bioremediation of Uranium and Harvesting Electrical Energy from Organic Matter
Research Partners: The Institute for Genomic Research, Rockville, MD; Argonne National Laboratory; University of Tennessee, Memphis.
This team will study a family of microbes with the potential for uranium bioremediation and, remarkably, for production of electricity through their ability to transfer electrons to electrodes. The research's goal is to develop computational models that can predict the activity of communities of these microbes in their natural environment. This knowledge in turn can predict the success of bioremediation and energy production under different environmental conditions.
Cooperative Agreement with Harvard Medical School $15 million over 5 years
Microbial Ecology, Proteogenomics and Computational Optima
Research Partners: Massachusetts Institute of Technology, Cambridge, MA; Brigham and Women's Hospital, Boston, MA; Massachusetts General Hospital, Boston, MA
This team will study two different microbes -- one that plays a significant role in earth's carbon cycle, and another with broad metabolic diversity. The team will study the proteins and protein-protein interactions in these microbes, the gene regulatory networks that control the production of these proteins and the behavior of these microbes as complex environmental communities. The
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Contact: Jill Schroeder
202-586-4940
DOE/Oak Ridge National Laboratory
31-Jul-2002