HOME >> BIOLOGY >> NEWS
Environmental enrichment reverses learning impairments caused by lead poisoning

Environmental enrichment that stimulates brain activity can reverse the long-term learning deficits caused by lead poisoning, according to a study conducted by researchers at the Johns Hopkins Bloomberg School of Public Health. It has long been known that lead poisoning in children affects their cognitive and behavioral development. Despite significant efforts to reduce lead contamination in homes, childhood lead poisoning remains a major public health problem with an estimated 34 million housing units in the United States containing lead paint.

The Hopkins study is the first to demonstrate that the long-term deficits in cognitive function caused by lead can be reversed and offers a basis for the treatment of childhood lead intoxication. The findings appear in the online edition of the Annals of Neurology.

"Lead exposure during development causes long-lasting deficits in learning in experimental animals, but our study shows for the first time that these cognitive deficits are reversible," said lead author Toms R. Guilarte, PhD, professor of environmental health sciences at the Johns Hopkins Bloomberg School of Public Health. "This study is particularly important for two reasons. First, it was not known until now whether the effects of lead on cognitive function were reversible. Secondly, the environmental enrichment that reversed the learning deficits was administered after the animals were exposed to lead. Environmental enrichment could be a promising therapy for treating millions of children suffering from the effects of lead poisoning," added Dr. Guilarte.

For their study, Dr. Guilarte, graduate student Christopher Toscano, research technologist Jennifer McGlothan, and research associate Shelley Weaver observed groups of leadtreated or non-treated (control) rats that were raised in an enriched environment. Enrichment cages were multi-level, containing toys, a running wheel, a hammock, platforms, tunnels, and housed multiple animals. Littermates
'"/>

Contact: Tim Parsons
paffairs@jhsph.edu
410-955-6878
Johns Hopkins University Bloomberg School of Public Health
26-Nov-2002


Page: 1 2

Related biology news :

1. Environmental issues center of Inland Northwest Research Alliance 4th Annual Symposium
2. Environmental decontamination, greenhouse gases, and the genome of a methane-loving bacterium
3. Environmental costs of home construction lower with wise choice, reuse of building materials
4. NIH funds Breast Cancer and the Environmental Research Center at Fox Chase Cancer Center
5. UCR graduate student wins best poster at Environmental Mutagen Society Meeting
6. Jane Goodall to receive 2003 Global Environmental Citizen Award
7. Jane Goodall to receive 2003 Environmental Citizen Award
8. Environmental influences play significant role on experiments
9. School of public health launches CDC Center for Excellence in Environmental Public Health Tracking
10. Brookhaven Lab scientist wins Environmental Mutagen Society Award
11. Environmental costs may be higher than you think

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/10/2019)... ... October 10, 2019 , ... Mindray, a ... attendees of the American Society of Anesthesiologists 2019 Annual Meeting to visit exhibit ... 19-21 in Orlando, Florida, and will provide more than 14,000 healthcare professionals from ...
(Date:10/8/2019)... ... October 07, 2019 , ... ... of imaging modalities such as optical projection tomography, optical coherence tomography, echocardiogram, light ... to generate these data sets inhouse, a lot of research groups struggle with ...
(Date:10/4/2019)... (PRWEB) , ... October 03, 2019 , ... Mount Sinai ... that cells hand down from one generation to the next. In a study published ... modulate the activity of this enzyme, leading to cancers and other diseases. , “DNA ...
Breaking Biology News(10 mins):
(Date:10/3/2019)... ... 2019 , ... Murrieta Genomics , the launch pad for genomic sequencing ... Silicon Valley at a special Life Science showcase event on October 10th, ... JJ Lake Business Center located at 340 E. Middlefield Road in Mountain View, California. ...
(Date:9/30/2019)... ... September 30, 2019 , ... The September 2019 edition ... , is now available online on the company’s global website. The Bridge features ... diffraction, fluorescence and imaging, and presents articles, scientific papers and news reports. ...
(Date:9/24/2019)... ... September 24, 2019 , ... Personalized ... training and site qualification for clinical trial sites and physician investigators. The ... potential clinical trial participants. , Clinical trial sites are currently located in San ...
(Date:9/17/2019)... N.J. (PRWEB) , ... September 17, 2019 , ... ... announced that Julie Delaney, Director, Project and Clinical Supplies Management, Asia Pacific (APAC) ... the One Farrer Hotel, Singapore, on Sept. 25-26, 2019. , On Thursday, Sept. ...
Breaking Biology Technology:
Cached News: