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Enzyme discovery sheds light on causes of rare disease, cancer

ntific inquiry for those who have the disease and their families, said David Frohnmayer, president of the University of Oregon in Eugene and a spokesman for the Fanconi Anemia Research Fund, www.fanconi.org. He and his wife, Lynn, helped incorporate the Fund in 1989. Two of their daughters have died of complications from the disease.

"Anything that can be found to further explain the FA complex and its functions is extremely important not only for the people who suffer from this disorder, but for the world of scientific discovery at the molecular level generally and especially those interested in DNA repair and cancer," Frohnmayer said. "This is the kind of discovery that takes a rare orphan disease and puts it in the mainstream of important science that affects the lives of millions of people."

In addition to NIA, researchers at the Baylor College of Medicine in Houston, the Oregon Health & Science University in Portland, and the Free University Medical Center in Amsterdam, The Netherlands, contributed to this work.


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Contact: Doug Dollemore
dollemod@nia.nih.gov
301-496-1752
NIH/National Institute on Aging
14-Sep-2003


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