HOME >> BIOLOGY >> NEWS
Epilepsy: Signals 'brake' in brain impaired

To date epilepsy research has mainly concentrated on the transmission of the nerve cell signals to what are known as the synapses. However, recent observations by medical researchers from the US, France and the University of Bonn support the idea that in 'falling sickness' the signal processing in the nerve cells (neurons) is altered: normally specific ion channels absorb the neuronal activity. In rats suffering from epilepsy, however, this signals brake seems impaired: they have far fewer functioning ion channels than healthy rats. The results are published in the latest edition of the prestigious scientific journal 'Science' (23rd July, vol. 305, no. 5683). They offer hope of new therapeutic possibilities.

Epilepsy is a common disease: in Germany alone there are 600,000 people whose nerve cells in the brain occasionally switch from healthy chaos to common mode. The result of the uncontrolled mass discharge of neurons is loss of consciousness and spastic convulsions of the muscles, during which those affected can seriously injure themselves. Yet how this synchronised paroxysmic activity develops at the level of nerve cells is still largely a mystery.

Nerve cells are interlinked via a large number of branching networks through which they communicate with each other. Each neuron has a series of dendrites which receive signals from other neurons at what are known as synapses. The cell 'processes' these incoming signals like a kind of biological microprocessor and transmits as a result electrical pulses via a special projection, the axon, to the dendrites of other neurons. Many epilepsy researchers have up to now assumed that when epilepsy occurs this communication between the cells does not work properly because the transmission of the signals to the synapses is impaired. However, the Bonn researchers in conjunction with their US colleagues and a research team from Marseilles discovered in the case of epileptic rats that the signal processing is not
'"/>

Contact: Professor Heinz Beck
heinz.beck@ukb.uni-bonn.de
49-228-287-9109
University of Bonn
28-Jul-2004


Page: 1 2 3

Related biology news :

1. Reproductive Signals Affect Lifespan In Roundworm C. Elegans, Offering Possible Insight Into Human Aging Process
2. Cell Suicide Prevented By Survival Signals
3. Toxic Protein That Interferes With Brain Signals May Trigger Onset Of Alzheimers Disease
4. Trial shows which brain cancer patients benefit from temozolomide
5. Targeted therapy knocks out pediatric brain cancer in mice
6. New way to protect brain from stroke damage
7. Chemical signals health of brain cells Symposium
8. DHA-rich diet protects brain from Alzheimers damage, UCLA study shows
9. Decreasing toxins in brains of Alzheimers patients keep cognitive deficits at bay
10. Genetic clues found for common congenital brain disorder
11. Marijuana ingredient inhibits VEGF pathway required for brain tumor blood vessels

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/28/2017)... , March 28, 2017 The ... Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video Analytics, ... Region - Global Forecast to 2022", published by MarketsandMarkets, ... 2016 and is projected to reach USD 75.64 Billion ... and 2022. The base year considered for the study ...
(Date:3/24/2017)... 24, 2017 The Controller General of Immigration from ... Abdulla Algeen have received the prestigious international IAIR Award for the ... Continue Reading ... ... Controller Abdulla Algeen (small picture on the right) have received the IAIR ...
(Date:3/23/2017)... The report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based ... to 2022", published by MarketsandMarkets, the market is expected to be worth USD ... 2022. Continue Reading ... ... ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... and LAGUNA HILLS, Calif. , Oct. ... Cancer Research, London (ICR) and University ... SKY92, SkylineDx,s prognostic tool to risk-stratify patients with multiple myeloma ... MUK nine . The University of Leeds ... partly funded by Myeloma UK, and ICR will perform the ...
(Date:10/10/2017)... ... 2017 , ... San Diego-based team building and cooking events company, Lajollacooks4u, has ... The bold new look is part of a transformation to increase awareness, appeal to ... period. , It will also expand its service offering from its signature gourmet cooking ...
(Date:10/10/2017)... 10, 2017 International research firm Parks Associates announced ... at the TMA 2017 Annual Meeting , October 11 in ... residential home security market and how smart safety and security products impact ... Parks Associates: Smart Home ... "The residential security market has ...
(Date:10/9/2017)... DIEGO , Oct. 9, 2017  BioTech ... biological mechanism by which its ProCell stem cell ... critical limb ischemia.  The Company, demonstrated that treatment ... amount of limbs saved as compared to standard ... the molecule HGF resulted in reduction of therapeutic ...
Breaking Biology Technology:
Cached News: