HOME >> BIOLOGY >> NEWS
Estrogen found as link between obesity and breast cancer in postmenopausal women

PHILADELPHIA (August 13, 2003) Researchers have known that obesity is associated with an increased risk of breast cancer in postmenopausal women, but a new study now explains why. According to research published in the August 20, 2003, issue of the Journal of the National Cancer Institute obesity increases the risk of breast cancer in postmenopausal women by increasing the amount of estrogens in the blood. High levels of estrogen definitively have been linked as a causative factor for breast cancer.

The finding was reported by the Endogenous Hormones and Breast Cancer Collaborative Group. Joanne F. Dorgan, M.P.H, Ph.D., an epidemiologist at Fox Chase Cancer Center, is the lead investigator of one of eight cohorts included in the analysis.

"We've known that postmenopausal women who are overweight have an increased risk of breast cancer, and the risk also is higher in women who have higher levels of estrogens in their blood," said Dorgan. "Our results suggest that obesity increases breast cancer risk in postmenopausal women by increasing serum concentrations of estrogens."

For the study, researchers analyzed the blood donated by women in eight cohorts in the United States, Europe and Asia. All the women were cancer-free and were not using hormone replacement therapy when the blood was collected. The women were followed for two to 12 years and 624 women developed breast cancer. Hormones in their blood were compared with the hormones from 1,640 cancer-free women who were the same age when blood was donated as the women who developed breast cancer. Obesity was measured by body mass index (BMI), a measure of weight that is adjusted for height.

Most of the established risk factors for breast cancer are either fixed (family history and genotype) or not amenable to modification (age at menarche, number of and ages at pregnancy, age at menopause).

"This is an example of a risk factor that a woman can control," Dorgan said. "
'"/>

Contact: Karen Carter Mallet
k_carter@fccc.edu
215-728-2700
Fox Chase Cancer Center
19-Aug-2003


Page: 1 2

Related biology news :

1. Estrogen promotes gender differences in brains response to stress
2. Estrogen receptor-a disruption and vasodilation in coronary arteries
3. Estrogen improves short term memory and oral reading in midlife postmenopausal women
4. Estrogens as antioxidants reducing heart disease in younger postmenopausal women
5. Estrogen patch compared to pill minimizes cardiovascular risk factor in postmenopausal women
6. Estrogen and personality in women
7. Estrogen linked to more efficient regulation of a womans heartbeat
8. Estrogen may protect against breast cancer
9. Estrogen combined with calcium and vitamin D may prevent tooth loss
10. Estrogen found in soy stimulates human breast-cancer cells in mice
11. Estrogen doesnt prevent second strokes: protective effects of hormone replacement therapy challenged

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/28/2017)... , March 28, 2017 The ... Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video Analytics, ... Region - Global Forecast to 2022", published by MarketsandMarkets, ... 2016 and is projected to reach USD 75.64 Billion ... and 2022. The base year considered for the study ...
(Date:3/24/2017)... 24, 2017 The Controller General of Immigration from ... Abdulla Algeen have received the prestigious international IAIR Award for the ... Continue Reading ... ... Controller Abdulla Algeen (small picture on the right) have received the IAIR ...
(Date:3/23/2017)... The report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based ... to 2022", published by MarketsandMarkets, the market is expected to be worth USD ... 2022. Continue Reading ... ... ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... and LAGUNA HILLS, Calif. , Oct. ... Cancer Research, London (ICR) and University ... SKY92, SkylineDx,s prognostic tool to risk-stratify patients with multiple myeloma ... MUK nine . The University of Leeds ... partly funded by Myeloma UK, and ICR will perform the ...
(Date:10/10/2017)... ... 2017 , ... San Diego-based team building and cooking events company, Lajollacooks4u, has ... The bold new look is part of a transformation to increase awareness, appeal to ... period. , It will also expand its service offering from its signature gourmet cooking ...
(Date:10/10/2017)... 10, 2017 International research firm Parks Associates announced ... at the TMA 2017 Annual Meeting , October 11 in ... residential home security market and how smart safety and security products impact ... Parks Associates: Smart Home ... "The residential security market has ...
(Date:10/9/2017)... DIEGO , Oct. 9, 2017  BioTech ... biological mechanism by which its ProCell stem cell ... critical limb ischemia.  The Company, demonstrated that treatment ... amount of limbs saved as compared to standard ... the molecule HGF resulted in reduction of therapeutic ...
Breaking Biology Technology:
Cached News: