Estrogen lifts mood in perimenopause

ponded to placebo. Among depression symptoms that improved with the hormone were early morning awakening, loss of enjoyment, sadness and irritability Among symptoms that failed to improve were sexual interest and disturbed sleep.

Blood concentrations of estrogen (estradiol) prior to the study or after hormone treatment did not predict therapeutic response. This suggests that the beneficial effects of estrogen aren't mediated by correcting abnormally low levels of the hormone. Rather, Schmidt and Rubinow suggest that some women may be especially sensitive to changing hormone levels. As with disorders like PMS and post-partum depression, such hormonal changes appear to be necessary, but not sufficient, to trigger perimenopausal depression, say the researchers, who are attempting to identify the still-unknown underlying predisposing factors. Doctors often prescribe estrogen to protect perimenopausal women from osteoporosis and heart disease, but long-term use of estrogen replacement may increase a woman's risk of breast and uterine cancer. In the future, more specific-acting medications that work through estrogen receptors may be engineered to selectively enhance bone, blood lipids and brain tissue without adversely affecting breast and uterine tissue, the researchers suggest.


Contact: Jules Asher
NIH/National Institute of Mental Health

Page: 1 2

Related biology news :

1. Estrogen promotes gender differences in brains response to stress
2. Estrogen receptor-a disruption and vasodilation in coronary arteries
3. Estrogen improves short term memory and oral reading in midlife postmenopausal women
4. Estrogen found as link between obesity and breast cancer in postmenopausal women
5. Estrogens as antioxidants reducing heart disease in younger postmenopausal women
6. Estrogen patch compared to pill minimizes cardiovascular risk factor in postmenopausal women
7. Estrogen and personality in women
8. Estrogen linked to more efficient regulation of a womans heartbeat
9. Estrogen may protect against breast cancer
10. Estrogen combined with calcium and vitamin D may prevent tooth loss
11. Estrogen found in soy stimulates human breast-cancer cells in mice

Post Your Comments:

(Date:11/19/2015)... VIEW, Calif. , Nov. 19, 2015  Based ... market, Frost & Sullivan recognizes BIO-key with the 2015 ... Leadership. Each year, Frost & Sullivan presents this award ... product line catering to the needs of the market ... the product line meets and expands on customer base ...
(Date:11/17/2015)... , November 17, 2015 Paris ... 2015.   --> Paris from 17 ... DERMALOG, the biometrics innovation leader, has invented the first ... fingerprints on the same scanning surface. Until now two different ... Now one scanner can capture both on the same ...
(Date:11/16/2015)... 2015  Synaptics Inc. (NASDAQ: SYNA ), ... announced expansion of its TDDI product portfolio with ... and display driver integration (TDDI) solutions designed to ... TDDI products add to the previously-announced TD4300 ... resolution), and TD4322 (FHD resolution) solutions. All four ...
Breaking Biology News(10 mins):
(Date:11/30/2015)... 1, 2015  An interventional radiology technique shows promise for ... results of a study being presented today at the annual ... (RSNA). --> ... by interventional radiologists as a way to stop bleeding in ... a means of treating obesity is new. Mubin ...
(Date:11/30/2015)... includes an MPP licen ... niversity , s Solid Drug Nanoparticle (SDN) Technology ; ... up through cost cuts of priority ... based anywhere in the world will have the right to make, use and distribute ... where licensees based anywhere in the world will have the right to make, use ...
(Date:11/30/2015)... 2015 Harvard Apparatus Regenerative Technology, Inc. ... developing bioengineered organ implants for life-threatening conditions, today ... NASDAQ Stock Market that it has regained compliance ... noted that as a result of the closing ... $1.00 per share for more than ten consecutive ...
(Date:11/30/2015)... Md. , Nov. 30, 2015 ... development company committed to the fostering and monetization ... the current and prospective initiatives designed to create ... Chief Executive Officer of Spherix. "Based on published ... future licensees exceeds $50 billion and Spherix will ...
Breaking Biology Technology:
Cached News: