HOME >> BIOLOGY >> NEWS
European researchers tackle mitosis

Scientists at the European Molecular Biology Laboratory (EMBL) join forces with top scientists from eleven research institutes in Austria, Germany, Italy, France and the United Kingdom for "MitoCheck" the largest integrated research project on cell cycle control within the European Commission's 6th Framework Programme (FP6). The partners will receive an 8.5 million Euro grant to address a fundamental question: How is cell division regulated?

Cell division (or "mitosis") is one of the key processes of life. Mistakes during mitosis can cause infertility and mental retardation, and can contribute to cancer. For the most part, mitosis is still poorly understood. Scientists do know that protein kinases a certain type of enzyme play a key role, but researchers don't know how these enzymes bring about the important changes in cells that cause them to divide. To understand cell division in a comprehensive manner, the MitoCheck consortium of European scientists will systematically hunt for all genes that are required for division and then check the products of these genes to see how they are regulated by mitotic kinases.

"This project is vital to understanding one of the most basic processes of life - making two cells out of one. Here at EMBL, we will identify which genes are required for mitosis by suppressing them gene-by-gene in live human cells and testing whether they can still divide afterwards," notes Jan Ellenberg, EMBL Group Leader and co-initiator of the MitoCheck project.

To achieve this, EMBL scientists use a method called "RNA interference," where RNA molecules can target and silence specific genes involved in mitosis. Another MitoCheck partner, the Max-Planck Institute of Cell Biology and Genetics in Dresden will provide a vast library of these molecules. About 20,000 genes will be suppressed one-by-one and EMBL researchers will make movies of the cells undergoing division, using sophisticated microscopes developed by Rainer Pepperk
'"/>

Contact: Trista Dawson
dawson@embl.de
49-622-138-7452
European Molecular Biology Laboratory
15-Jul-2004


Page: 1 2

Related biology news :

1. European common frog found to use novel mating strategy
2. Zoonotic diseases - European scientists unite to fight diseases
3. Second call for proposals for the European Young Investigator Award
4. Common call for action on European Research Council (ERC)
5. EURYI Award given for the first time to 25 young European researchers
6. Key principles for the foundation of a European Research Council (ERC)
7. EC boosts European electron microscopy research
8. Plants for the future: A European vision for plant biotechnology towards 2025
9. European Commission approves Herceptin + Taxotere as 1st-line therapy in HER2-positive breast cancer
10. Limited climate tracking in European trees despite 10,000 years of postglacial warmth
11. ESA consults European science community on candidate Earth Explorer missions

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/8/2019)... ... September 06, 2019 , ... The Board of Directors of ... the respective companies to proceed with a proposed business combination. After the ... a series of products leveraging the CRISPR-Chip technology. The closing of the ...
(Date:8/29/2019)... DIEGO (PRWEB) , ... August 28, 2019 , ... Lajollacooks4u ... The San Diego-based team building and cooking events company has seen record growth in ... Teams, such as Amazon, ServiceNow, Vistage and Illumina, have all visited the company’s La ...
(Date:8/27/2019)... ... August 27, 2019 , ... e3 ... to announce that it has partnered with Bertec, a leading manufacturer of force ... Balance Advantage systems, a full line of clinical systems for both assessment and ...
Breaking Biology News(10 mins):
(Date:8/23/2019)... Fla. (PRWEB) , ... August 22, 2019 , ... ... explore new drug delivery modalities and is scheduled to broadcast 4Q/2019. Check your ... Science’s (Avro) state-of-the-art skin patches for generic drug delivery. Focusing on therapeutics for ...
(Date:8/7/2019)... (PRWEB) , ... August 07, 2019 , ... Locus Agricultural ... breakthrough line of soil amendments (soil “probiotics”), including Rhizolizer ® , which is ... year—the largest impact any approach has offered to date. Results from the treatment of ...
(Date:8/4/2019)... (PRWEB) , ... August 02, 2019 , ... Cirtec Medical ... invasive devices, today announced that it has begun construction on a 30,000 sq. ft. ... 15 miles from San Jose. , The facility, which is expected to be ...
(Date:7/19/2019)... ... 18, 2019 , ... World renowned two-time Everest summiter Ravichandran ... California-based charity Coalition Duchenne for its 9th Annual Expedition Mt. Kinabalu in Sabah, ... for Duchenne muscular dystrophy and was founded by Sabahan Catherine Jayasuriya. , ...
Breaking Biology Technology:
Cached News: