HOME >> BIOLOGY >> NEWS
Even moderate caloric restriction lowers cancer risk in mice

A new National Cancer Institute study reported April 23 by Dr. Volker Mai at the Experimental Biology 2002 meeting in New Orleans shows that even moderate caloric restriction reduced by 60 percent the number of precancerous intestinal polyps in mice at high risk of gastrointestinal cancers (mice with the same genetic mutation seen in some humans who develop these cancers). Dont think you can eat less? Then eat better. Animals eating as much as they wanted of a diet high in olive oil, fruits and vegetables also had a third fewer polyps than control mice.

Thats good news, says Dr. Mai, since this moderate caloric restriction and/or the use of a diet in which fat came from olive oil are more likely to be followed by humans and have been shown to have broad health benefits even beyond an effect on gastrointestinal cancer risk. The findings are more troubling, he adds, when you think about the continuing trend of high caloric food intake observed in most developed nations. How much is too much? Working with a well-proven mouse model of intestinal cancer, the NCI researchers allowed some mice to eat as much food as they wanted. As mice will, they ate almost all the time, with weight gain to show for it. The researchers measured the mices food intake and limited similar mice to only 60 percent of the amount. This satisfied all their nutritional requirements and provided a goodly amount of food to eat as well. The result: the number of the precancerous polyps also went down by 60 percent compared to the mice eating as much as they wanted.

Previous mouse studies, like epidemiological studies of humans, have shown that what gets eaten also has an effect on colorectal cancers. So Dr. Mai and his colleagues at NCI compared the number of polyps in mice on a high fat diet, mice on a healthy diet with olive oil and fruit and vegetable extract, and mice on the standard laboratory mouse diet. Mice consuming a diet high on fruits and vegetables had 33 perce
'"/>

Contact: Sarah Goodwin
eb2press@bellsouth.net
770-722-0155
Federation of American Societies for Experimental Biology
23-Apr-2002


Page: 1 2

Related biology news :

1. Longer-term, moderate exercise improves immune activity
2. FDA approves Raptiva (efalizumab) for chronic moderate-to-severe plaque psoriasis
3. NIH told regular and moderate exposure to sunlight is the key to preventing chronic disease
4. New study ties moderate beer drinking to lower heart attack risk
5. Light to moderate drinking during pregnancy can affect adolescent growth
6. Actonel significantly reduced moderate and severe vertebral fractures
7. Women who drink moderately do not face a longer wait to become pregnant
8. Scientists identify compounds that mimic calorie restriction
9. Lake restrictions make lakeshore property more valuable
10. MIT helps unlock life-extending secrets of calorie restriction
11. UF study: Calorie restriction reduces age-related brain cell death

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/4/2017)... NEW YORK , April 4, 2017   ... solutions, today announced that the United States Patent and ... The patent broadly covers the linking of an iris ... the same transaction) and represents the company,s 45 th ... our latest patent is very timely given the multi-modal ...
(Date:3/30/2017)... March 30, 2017 The research team of ... three-dimensional (3D) fingerprint identification by adopting ground breaking 3D fingerprint minutiae ... realm of speed and accuracy for use in identification, crime investigation, ... cost. ... A research ...
(Date:3/28/2017)... 2017 The report "Video Surveillance ... Servers, Storage Devices), Software (Video Analytics, VMS), and Service ... Forecast to 2022", published by MarketsandMarkets, the market was ... projected to reach USD 75.64 Billion by 2022, at ... base year considered for the study is 2016 and ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... October 11, 2017 , ... Singh Biotechnology today announced ... to SBT-100, its novel anti-STAT3 (Signal Transducer and Activator of Transcription 3) B ... to cross the cell membrane and bind intracellular STAT3 and inhibit its function. ...
(Date:10/10/2017)... -- International research firm Parks Associates announced today that ... TMA 2017 Annual Meeting , October 11 in Scottsdale, Arizona ... market and how smart safety and security products impact the competitive landscape. ... Parks Associates: Smart Home Devices: Main Purchase ... "The residential security market has experienced continued growth, ...
(Date:10/9/2017)... ... October 09, 2017 , ... The award-winning American Farmer television series will ... American Farmer airs Tuesdays at 8:30aET on RFD-TV. , With global population estimates ... of how to continue to feed a growing nation. At the same time, many ...
(Date:10/7/2017)... ... October 06, 2017 , ... ... technologies, launched its ProxiMeta™ Hi-C metagenome deconvolution product, featuring the first commercially ... cloud-based bioinformatics software to perform Hi-C metagenome deconvolution using their own facilities, ...
Breaking Biology Technology:
Cached News: