Evidence For Genetic Effects On The Behavior Of Normal Two-Week ...( berelated to 'novelty seeking' across ...)

be related to 'novelty seeking' across four behavioral clusters pertinent to newborn temperament. The effect of the short variant of the serotonin transporter gene promoter, which some investigators have found to be associated with 'neuroticism,' in those infants was to lower their NBAS orientation scores. Orientation may be understood as an active, attentive and searching process for infants, perhaps a neonatal precursor to adult novelty seeking behavior. In infants as in adults, personality appears, therefore, to be partially determined by the developmental interaction between underlying genetic mechanisms contributing respectively to behavioral activation and inhibition. This study further suggests that it might be possible in the future, by combining very early in life genetic and behavioral tests, to detect antecedents of adult personality traits allowing clinicians and parents to more intelligently guide the newborn's psychological development.

For information on this Molecular Psychiatry article, please contact the author:
Dr. Richard P. Ebstein
at the Research Laboratory
S. Herzog Memorial Hospital
P.O. Box 35300
Jerusalem 91351
Israel
Tel: 972-2-5316855
Fax: 972-2-5316853
ebstein@netmedia.net.il
reference:Molecular Psychiatry 1998; 3 (May): in press

This article is from the May 1998 issue of Molecular Psychiatry, an independent peer-reviewed journal published by Stockton Press-Macmillan Press.

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Molecular Psychiatry
25-May-1998

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