HOME >> BIOLOGY >> NEWS
Evidence suggests food preservatives may help prevent cavities

ter researcher Basil Bibby suggested that fluoride inhibits the bacteria that feed on sugars and secrete the acid that eats through tooth enamel and causes cavities. But many other researchers discarded that hypothesis, instead relying on evidence that fluoride allows teeth to remineralize, helping to fill in small cavities a little bit like a road crew fills in potholes, before they grow even bigger.

Now, Marquis and others have vindicated Bibby by showing that fluoride does affect bacteria directly. In his laboratory, Marquis has shown that fluoride and food preservatives knock out bacteria by pushing them to exhaustion. Though bacteria like streptococcus mutans thrive in the high-acid environment that they create along the surface of teeth and in dental plaque, the bacteria must maintain a lower acidity level within themselves. But fluoride and food preservatives make this difficult. Both take molecular actions that lower the pH within bacteria by continually bringing protons into the cells. Bacteria pump these protons back out, but like an athlete who continually must toss a heavy medicine ball over a fence, the cell soon uses up all its energy pumping the protons back out. Without energy, the cell shuts down and stops producing acid.

"The acid from these bacteria is what causes enamel to dissolve," says Marquis, professor of microbiology and immunology. "Fluoride and preservatives like benzoate prevent the bacteria from acidifying the plaque and causing cavities. The bacteria are still there -- you have to take a tooth brush to get rid of them -- but they're not causing damage."

In his laboratory, Marquis has also shown that the common medicine ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), also acts like fluoride and food preservatives in the way it inhibits bacteria. Again picking up on that basic research, Bowen's team has just published results showing that ibuprofen also enhances fluoride's action, dramati
'"/>

Contact: Tom Rickey
trickey@admin.rochester.edu
716-275-7954
University of Rochester
7-Apr-2000


Page: 1 2 3 4

Related biology news :

1. Evidence builds for potential new cancer drug target
2. Evidence for sympatric speciation by host shift in the sea
3. Evidence for the impact of climate change on deep-sea biodiversity
4. Evidence for fat hormone target in brain
5. Evidence of nanobacterial-like structures found in human calcified arteries and cardiac valves
6. Evidence shows the heart has stem cells able to regenerate muscle tissue lost to disease, wear
7. Evidence for orangutan culture
8. Evidence suggests that standard smallpox vaccine offers long-term immunity
9. Evidence that adults stem cells differentiate like embryonic stem cells published in Nature
10. When Shewanella meets goethite: Evidence found of recognition between animate and inanimate objects
11. Evidence links protein damage to Parkinsons

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/23/2017)... Research and Markets has announced the addition of the "Global ... 2025" report to their offering. ... The Global Vehicle Anti-Theft System Market is ... next decade to reach approximately $14.21 billion by 2025. ... all the given segments on global as well as regional levels ...
(Date:3/22/2017)... , March 21, 2017 Vigilant ... company serving law enforcement agencies, announced today the appointment ... as director of public safety business development. ... law enforcement experience, including a focus on the aviation ... his most recent position, Mr. Sheridan served as the ...
(Date:3/16/2017)... -- CeBIT 2017 - Against identity fraud with DERMALOG solutions "Made in ... ... Used combined in one project, multi-biometric solutions provide a crucial contribution against identity fraud. (PRNewsFoto/Dermalog ... Used combined in one project, multi-biometric solutions provide ... ...
Breaking Biology News(10 mins):
(Date:6/22/2017)... ... June 21, 2017 , ... Building on the success ... and more informative on the very latest developments in radical life extension. RAADfest combines ... a festival, and the empowerment of personal development, making it the largest most comprehensive ...
(Date:6/22/2017)... Prussia, PA (PRWEB) , ... June 22, 2017 ... ... knowledge and superior results to clients throughout the biopharma and life sciences industries, ... changes the industry is seeing. Tunnell’s Kip Wolf will be speaking on “The ...
(Date:6/20/2017)... ... June 20, 2017 , ... ... CTNext board of directors has formed a Higher Education Entrepreneurship Advisory Committee to ... of institution presidents and other high-ranking representatives from 35 higher education institutions across ...
(Date:6/20/2017)... ... June 20, 2017 , ... National executive search ... with extensive assay development and biomarker expertise, as VP of Scientific Affairs at ... specializing in bio-analytical assay development and sample testing services. The organization acts as ...
Breaking Biology Technology:
Cached News: