Evidence suggests food preservatives may help prevent cavities

ter researcher Basil Bibby suggested that fluoride inhibits the bacteria that feed on sugars and secrete the acid that eats through tooth enamel and causes cavities. But many other researchers discarded that hypothesis, instead relying on evidence that fluoride allows teeth to remineralize, helping to fill in small cavities a little bit like a road crew fills in potholes, before they grow even bigger.

Now, Marquis and others have vindicated Bibby by showing that fluoride does affect bacteria directly. In his laboratory, Marquis has shown that fluoride and food preservatives knock out bacteria by pushing them to exhaustion. Though bacteria like streptococcus mutans thrive in the high-acid environment that they create along the surface of teeth and in dental plaque, the bacteria must maintain a lower acidity level within themselves. But fluoride and food preservatives make this difficult. Both take molecular actions that lower the pH within bacteria by continually bringing protons into the cells. Bacteria pump these protons back out, but like an athlete who continually must toss a heavy medicine ball over a fence, the cell soon uses up all its energy pumping the protons back out. Without energy, the cell shuts down and stops producing acid.

"The acid from these bacteria is what causes enamel to dissolve," says Marquis, professor of microbiology and immunology. "Fluoride and preservatives like benzoate prevent the bacteria from acidifying the plaque and causing cavities. The bacteria are still there -- you have to take a tooth brush to get rid of them -- but they're not causing damage."

In his laboratory, Marquis has also shown that the common medicine ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), also acts like fluoride and food preservatives in the way it inhibits bacteria. Again picking up on that basic research, Bowen's team has just published results showing that ibuprofen also enhances fluoride's action, dramati

Contact: Tom Rickey
University of Rochester

Page: 1 2 3 4

Related biology news :

1. Evidence builds for potential new cancer drug target
2. Evidence for sympatric speciation by host shift in the sea
3. Evidence for the impact of climate change on deep-sea biodiversity
4. Evidence for fat hormone target in brain
5. Evidence of nanobacterial-like structures found in human calcified arteries and cardiac valves
6. Evidence shows the heart has stem cells able to regenerate muscle tissue lost to disease, wear
7. Evidence for orangutan culture
8. Evidence suggests that standard smallpox vaccine offers long-term immunity
9. Evidence that adults stem cells differentiate like embryonic stem cells published in Nature
10. When Shewanella meets goethite: Evidence found of recognition between animate and inanimate objects
11. Evidence links protein damage to Parkinsons

Post Your Comments:
TAG: Evidence suggests food preservatives may help prevent cavities

(Date:9/24/2015)... Publiceringsförbud fram till: ... Kerv ( http://kerv.com ), det Londonbaserade ... första kontaktlösa betalningsring på kickstarter.com i ett ... för massproduktion via crowdfunding.       ... Kerv-bärare kan göra direkta kontaktlösa betalningar ...
(Date:9/10/2015)... Sept. 10, 2015 Pursuant Health has ... to create an interactive, image-based health risk assessment ... wellness kiosk.  The unique assessment quantifies user results ... that suggests an individual,s biological age based on ... measured by the kiosk. Comprised of ...
(Date:9/8/2015)... , Sept. 8, 2015  Affectiva, global ... Emotion as a Service, a new data solution, ... Based on Affectiva,s highly accurate and patented ... analytics capabilities, slated to transform industries such as ... development, retail, customer experience, online education, HR, automotive, ...
Breaking Biology News(10 mins):
(Date:10/9/2015)... Governor Tom Wolf announced today that Adaptimmune ... T-cell receptor cancer immunotherapy treatments, will create at least ... Pennsylvania , and today,s announcement ... high-paying jobs will be created with this project," said ... sustained funding for the life science sector and increased ...
(Date:10/9/2015)... Oct. 9, 2015  DePuy Synthes Trauma* announced today ... Q-PACK ®  Technology**, the only pre-hydrated demineralized cancellous ... procedures (foot and ankle, hand and wrist), including fusion, ... here at the 2015 Orthopaedic Trauma Association (OTA) Annual ... scaffold for new bone growth) and osteoinductive 2,3 ...
(Date:10/9/2015)... ... October 09, 2015 , ... ... the current methods of separating those cells from their surroundings for research, diagnostics, ... the cells. , To address this, Ann Arbor-based startup Akadeum Life Sciences ...
(Date:10/8/2015)... ... October 08, 2015 , ... Researchers at the University of Washington (UW) ... providing a new tool to study how diseases like dementia, Alzheimer's, and brain tumors ... and Ruikang Wang of the UW Department of Bioengineering, today in the Journal ...
Breaking Biology Technology:
Cached News: