HOME >> BIOLOGY >> NEWS
Evidence suggests food preservatives may help prevent cavities

ter researcher Basil Bibby suggested that fluoride inhibits the bacteria that feed on sugars and secrete the acid that eats through tooth enamel and causes cavities. But many other researchers discarded that hypothesis, instead relying on evidence that fluoride allows teeth to remineralize, helping to fill in small cavities a little bit like a road crew fills in potholes, before they grow even bigger.

Now, Marquis and others have vindicated Bibby by showing that fluoride does affect bacteria directly. In his laboratory, Marquis has shown that fluoride and food preservatives knock out bacteria by pushing them to exhaustion. Though bacteria like streptococcus mutans thrive in the high-acid environment that they create along the surface of teeth and in dental plaque, the bacteria must maintain a lower acidity level within themselves. But fluoride and food preservatives make this difficult. Both take molecular actions that lower the pH within bacteria by continually bringing protons into the cells. Bacteria pump these protons back out, but like an athlete who continually must toss a heavy medicine ball over a fence, the cell soon uses up all its energy pumping the protons back out. Without energy, the cell shuts down and stops producing acid.

"The acid from these bacteria is what causes enamel to dissolve," says Marquis, professor of microbiology and immunology. "Fluoride and preservatives like benzoate prevent the bacteria from acidifying the plaque and causing cavities. The bacteria are still there -- you have to take a tooth brush to get rid of them -- but they're not causing damage."

In his laboratory, Marquis has also shown that the common medicine ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), also acts like fluoride and food preservatives in the way it inhibits bacteria. Again picking up on that basic research, Bowen's team has just published results showing that ibuprofen also enhances fluoride's action, dramati
'"/>

Contact: Tom Rickey
trickey@admin.rochester.edu
716-275-7954
University of Rochester
7-Apr-2000


Page: 1 2 3 4

Related biology news :

1. Evidence builds for potential new cancer drug target
2. Evidence for sympatric speciation by host shift in the sea
3. Evidence for the impact of climate change on deep-sea biodiversity
4. Evidence for fat hormone target in brain
5. Evidence of nanobacterial-like structures found in human calcified arteries and cardiac valves
6. Evidence shows the heart has stem cells able to regenerate muscle tissue lost to disease, wear
7. Evidence for orangutan culture
8. Evidence suggests that standard smallpox vaccine offers long-term immunity
9. Evidence that adults stem cells differentiate like embryonic stem cells published in Nature
10. When Shewanella meets goethite: Evidence found of recognition between animate and inanimate objects
11. Evidence links protein damage to Parkinsons

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Evidence suggests food preservatives may help prevent cavities

(Date:12/10/2014)... , December 9, 2014 ... ITN,s BCARD Platform   ... enterprise meeting scheduling solutions for business-to-business (B2B) events, ... world leader in mobile near-field communication (NFC), Bluetooth ...      (Logo: http://photos.prnewswire.com/prnh/20140612/691055) , Jifflenow ...
(Date:12/5/2014)...  Tute Genomics, a leader in cloud-based solutions for ... funding led by UK-based Eurovestech. Peak Ventures and a ... round. "We are at a pivotal time ... and seeks new approaches for the diagnosis, treatment and ... MBA, and CEO of Tute Genomics. "One of the ...
(Date:12/3/2014)...   Marvin Test Solutions , a trusted ... military, aerospace, and manufacturing organizations, today announced the ... TS-900 PXI semiconductor test platform . The TS-960 ... to customers at a fraction of the footprint ... "Our semiconductor customers asked for ...
Breaking Biology News(10 mins):Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 3Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 2Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 3Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 3
(Date:12/22/2014)... HILL, N.C. , Dec. 22, 2014 /PRNewswire/ ... today announced that it has signed a letter ... company that has developed and patented a nanotechnology-based ... medical diagnostics products that enable rapid on-site collection ... alcohol use/abuse and health issues in an immediate, ...
(Date:12/22/2014)... ITRA Global, one of the largest organizations dedicated ... has further expanded its global reach with the affiliation ... Australia, reports Mylinda Vick, CCIM, Chairman of the ITRA ... ACORPP (Australian Corporate Property and Projects) , is a ... to a wide range of clients in the private ...
(Date:12/19/2014)... BioPlus Specialty Pharmacy (BioPlus), one of the nation’s ... Pharm.D. to the newly created position of Vice President ... Dr. Maroulis will continue to manage the entire specialty ... pharmacies as the company expands. Dr. Maroulis has been ... has served in many different capacities in the pharmacy, ...
(Date:12/19/2014)... , Dec. 19, 2014 Decision Resources Group ... grow at a 12 percent compound annual growth rate ... the aging population and the increasing adoption of dental ... will also spur demand for dental biomaterials ... implant and periodontal treatments. Other key findings ...
Breaking Biology Technology:ALNE Announces Intention To Acquire BioTechPharma 2ITRA Global Continues International Expansion in Perth and Brisbane, Australia 2BioPlus Specialty Pharmacy Promotes Dr. Nick Maroulis to Vice President of Specialty Pharmacy Services 2Latin American Dental Biomaterial Market Will Expand at a 12 Percent Annual Growth Rate Through 2023 2Latin American Dental Biomaterial Market Will Expand at a 12 Percent Annual Growth Rate Through 2023 3
Cached News: