HOME >> BIOLOGY >> NEWS
Excellent survival rates for liver cancer patients undergoing transplant

More than 60 percent of liver transplant patients with advanced liver cancer are still alive after five years, compared to nearly zero survival for those patients who did not undergo transplant, according to a study by Johns Hopkins researchers.

"This is good news for patients with liver cancer. If diagnosed early, transplantation is the treatment of choice for patients with liver cancer and advanced cirrhosis," says Paul Thuluvath, M.D., associate professor of medicine at Johns Hopkins and lead author of the report published in the Dec. 1, issue of the Journal of Clinical Oncology and available online after Oct. 27.

Thuluvath emphasizes that regular screening of patients with cirrhosis, a risk factor for liver cancer, is needed to detect the cancer early and insure the best possible outcome.

In addition to the favorable five-year survival rates, Thuluvath and colleagues found that survival rates increased steadily over the last decade, suggesting that criteria for patient selection established by other experts may assist physicians in selecting those patients most likely to respond well to the procedure.

Using the United Network for Organ Sharing (UNOS) database, the researchers collected data on 48,887 patients who underwent liver transplantation in the United States between 1987 and 2001. Patients were excluded if they had undergone multiple organ transplantation or retransplantation, were less than 18 years of age, or lacked survival data.

Of the remaining patients included in the final analysis, 985 had liver transplantation for liver cancer and 33,339 patients had liver transplantation for other reasons (control group). Both the liver cancer and control groups were divided into three different five-year time periods: 1987 1991, 1992 1996, and 1997 2001.

Researchers found significant and steady improvement in survival over time among liver transplant patients with liver cancer, especially in the last f
'"/>

Contact: Trent Stockton
tstockt1@jhmi.edu
410-955-8665
Johns Hopkins Medical Institutions
30-Oct-2003


Page: 1 2

Related biology news :

1. Enzyme maintaining chromosome ends is linked to bone cancer recurrence, decreased survival
2. Bad news for pathogenic bacteria: Scientists find protein essential for bacterial survival
3. Clue found on breast tumors distinguishes patients with better survival odds
4. Figs may inhibit growth and survival of harmful microbes in food
5. Study may improve survival of transplanted livers
6. Chromosome losses mean poor survival in childhood leukemia
7. Scientists identify six genes associated with survival in diffuse large B cell lymphoma
8. Predicting cancer patient survival with gene expression data
9. New approach limits damage after heart attack and improves survival, say Scripps Research scientists
10. Aggregation of cloned mouse embryos improves survival rate
11. UC Santa Barbara discovers cell survival gene may lead to treatments for degenerative diseases

Post Your Comments:
(Date:10/29/2014)... 2014, Beaverton, OR) New research presented at ... Conference in Houston, TX showed for the first ... infection in women using a readily available nutritional ... presented by Dr. Judith A. Smith, Pharm.D., associate ... Reproductive Sciences at The University of Texas Health ...
(Date:10/29/2014)... all the rage. Thousands of scientists worldwide are conducting ... titanium dioxide nanoparticles from sun creams can get through ... from electronic products are as hazardous for the lungs ... food can get into the blood via the intestinal ... are flowing – and the number of scientific projects ...
(Date:10/29/2014)... research potential of the Barcode of Life Data ... Biodiversity Data Journal (BDJ) used ... imported these into a human-readable text developed in manuscript ... were used to study the species distributions of ten ... , BOLD is originally designed to support the generation ...
Breaking Biology News(10 mins):HPV infections in women eradicated by AHCC, Japanese mushroom extract 2Nanosafety research: The quest for the gold standard 2Nanosafety research: The quest for the gold standard 3Go straight and publish: From Barcode of Life Data Systems to scholarly publishing systems 2
(Date:10/30/2014)... 2014 Whitehouse Laboratories has formally announced ... Testing and Package Test Capacity. Responding to growing demands ... dramatic increase in environmental chamber storage space that will ... aging samples to be securely held on site at ... expenditure has already taken place with the recent completion ...
(Date:10/30/2014)... Al Khaimah, UAE (PRWEB) October 30, 2014 ... appointment of Dr. James A. Manganello, Chairman of the Board, ... of The Bahamas. The appointment was made by the ... Bahamas on September 24th, 2014. , More than ... Therapy and Research Bill , Prime Minister Perry Christie said ...
(Date:10/30/2014)... , Oct. 30, 2014 A new ... Technology Partnership Practice, takes an in-depth look at ... outputs that have resulted over two different time frames: ... provides a view of future opportunities for investment growth.  ... Indiana report shows gains in innovation dollars ...
(Date:10/30/2014)... in the development of quantum technologies has been proposed ... published today (28 October) in Nature Communications , ... a new type of flexibly designed microscopic trap for ... and specialised superfast computers, often depend on harnessing the ... these tiny particles are hugely problematic because of the ...
Breaking Biology Technology:Whitehouse Labs Announces Major Capital Investment in Stability and Storage Testing Capacity 2Whitehouse Labs Announces Major Capital Investment in Stability and Storage Testing Capacity 3Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 2Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 3New report shows Indiana's gains in life sciences innovation capital outpace the nation 2New report shows Indiana's gains in life sciences innovation capital outpace the nation 3New report shows Indiana's gains in life sciences innovation capital outpace the nation 4New report shows Indiana's gains in life sciences innovation capital outpace the nation 5
Cached News: