Experimental Drug Derived From Snake Venom Shows Promise In Reversing Effects Of Stroke

NASHVILLE, Feb. 4 -- A stroke therapy derived from snake venom? According to researchers, it's not a snake oil story, but instead a possible new way to help people recover from the devastating effects of stroke.

Scientists announced the results of a 500-person trial examining the effects of an experimental stroke drug called ANCROD here today at the 24th American Heart Association International Conference on Stroke and Cerebral Circulation.

Researchers found that 42 percent of stroke victims treated with ANCROD within three hours of stroke onset had recovered the physical and mental abilities that they had prior to the stroke.

In comparison, 34 percent of those receiving an inert substance, or placebo, regained their previous faculties. However, stroke patients who received ANCROD were also at a higher risk of bleeding in the brain (5 percent of patients) when compared to those who received the placebo (2 percent).

ANCROD is not yet approved by the Food and Drug Administration for stroke treatment. Tissue plasminogen activator (TPA) is the only FDA-approved acute stroke treatment.

ANCROD is derived from the venom of a pit viper snake. Researchers discovered that in people who were bitten by the snake, blood failed to clot. Based on that observation, the venom was utilized as an anticoagulant, helping blood flow more freely through vessels.

"Like clot-dissolving drugs TPA and urokinase, the goal was for ANCROD to be administered within three hours of stroke onset," says the study's lead author, David Sherman, M.D. "Also, none of these three drugs are for use in patients who have hemorrhagic strokes, caused by a burst or leaking blood vessel in the brain."

There are sharp contrasts between the treatments, however, says Sherman.

TPA is administered in a single-dose, hour-long injection and results can be seen soon thereafter. ANCROD is given intravenously through

Contact: Brian Henry or Cathy Yarbrough
American Heart Association

Page: 1 2 3

Related biology news :

1. Experimental drug shown to block mutant protein causing blood disease
2. Experimental smallpox DNA vaccine protects primates from lethal monkeypox
3. Experimental smallpox vaccine protects against monkeypox in nonhuman primates
4. Experimental Biology 2004 - Translating the Genome
5. Experimental Biology 2004 meets in Washington, D.C. April 17-21
6. Experimental hantavirus vaccine elicits strong antibody response in primates
7. Experimental cancer drugs may halt events that lead to cardiac hypertrophy and heart failure
8. Experimental Biology 2003 meets in San Diego April 11-15
9. Experimental Biology 2003 meets in San Diego April 11-15
10. Experimental gene switch increases lifespan with no ill effects
11. Experimental therapy stops allergic reactions in mice

Post Your Comments:

(Date:8/12/2020)... Mich. (PRWEB) , ... August 11, 2020 , ... ... R&D subsidiary based in Princeton, NJ, have entered into license agreements with Housey ... and development. Both Roche and J&J have annual Research and Development spending ...
(Date:8/7/2020)... ... August 06, 2020 , ... Nine ... prestigious National STEM Scholar Program, a unique professional development program that provides advanced ... for middle school science teachers nationwide. , Created in partnership between the National ...
(Date:7/31/2020)... ... July 30, 2020 , ... BioFactura, Inc. ... awarded by the Joint Science & Technology Office—Chemical and Biological Defense (JSTO-CBD) of ... optimize, and scale-up a highly efficient mammalian cell culture-based bioprocess suitable to meet ...
Breaking Biology News(10 mins):
(Date:8/31/2020)... Del. (PRWEB) , ... August 29, 2020 , ... ... a new Animal Nutrition manufacturing capability in Wuxi, China. The new plant operation ... global quality standards and advanced technology. , “This facility will improve the ...
(Date:8/12/2020)... ... August 12, 2020 , ... Inc. magazine today revealed ... in FDA compliance consulting has been named on its annual Inc. 5000 list, ... a unique look at the most successful companies within the American economy’s most ...
(Date:7/31/2020)... ... July 29, 2020 , ... G-CON Manufacturing, the leader ... tagline, “BUILDING FOR LIFE.” The adoption of this taglines comes at a time ... track capacity to provide patients with urgently needed vaccines and other lifesaving pharmaceutical ...
(Date:7/31/2020)... MIAMI (PRWEB) , ... July 29, 2020 , ... ... nearly 200 of the top radiation centers in 16 countries, has reached its ... years, SDX® is now in routine use at top universities including University of ...
Breaking Biology Technology:
Cached News: