HOME >> BIOLOGY >> NEWS
Familial Cancer Syndrome Linked to Colorectal Cancer in Younger People

Important Factor in Limiting Risk of Additional Cancers in Patients and their Family Members

New York, January 28, 1999 -- Nearly one-fifth of patients who develop colorectal cancer at a young age (40 and younger) have a family history consistent with a familial colorectal cancer syndrome known as hereditary non-polyposis colorectal cancer (HNPCC), according to researchers at Memorial Sloan-Kettering Cancer Center.

The study, published in the current issue of Diseases of the Colon and Rectum, looked at 230 patients 40 years of age and younger who were diagnosed with colorectal cancer and found that nearly 20 percent of them had the HNPCC syndrome.

HNPCC is a dominantly inherited disorder, accounting for about five percent of all colorectal cancer cases. It is generally a fast-growing cancer that affects people primarily in their 40s. People who carry the genetic mutation for HNPCC have an 80 to 85 percent lifetime risk of developing colorectal cancer and are at increased risk of developing endometrial, ovarian, stomach, kidney, and other cancers. The criteria for a clinical diagnosis of HNPCC include: three first-degree relatives with colorectal cancer, spanning two generations, one of whom is less than 50 years of age at the time of diagnosis. This would exclude those with another type of inherited colorectal cancer called Familial Adenomatous Polyposis, a condition where people develop hundreds of colon polyps at a very young age.

"Individuals who develop colorectal cancer at a young age require special surveillance to protect them from developing other types of cancers," said Dr. Jose Guillem, Associate Attending Surgeon at Memorial Sloan-Kettering Cancer Center and lead author of the study. "By identifying and tracking individuals with HNPCC, we can intervene at an early stage and make appropriate, and where warranted, aggressive treatment decisions to prevent the development of additional colorectal and other cance
'"/>

Contact: Stacey Harris
harriss@mskcc.org
212-639-3573
Memorial Sloan-Kettering Cancer Center
1-Feb-1999


Page: 1 2

Related biology news :

1. Genetic, Familial Factors Influence ADHD, Not Necessarily Sex Of Child
2. Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases
3. 16th EORTC NCI AACR Symposium Molecular Targets and Cancer Therapeutics
4. 16th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
5. Cancer gene MYC emerging as key research target
6. Cancer patient, heal thyself
7. USC researcher named General Motors Cancer Research Scholar
8. Fox Chase Cancer Centers Alfred Knudson Jr. named 2004 Kyoto Prize winner
9. Wilex & Fox Chase Cancer Center begin trial w/ novel compound targeting tumor invasion & metastasis
10. Cancer drug resistance research leads to possible therapeutic target for Alzheimers disease
11. Fox Chase Cancer Center research shows kidney cancer can be diagnosed in urine

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2021)... ... March 25, 2021 , ... Phlexglobal announced ... Planet Group, has selected Phlexglobal and its innovative regulatory SaaS software, PhlexSubmission, as ... a comprehensive review of five regulatory software companies, with the review team including ...
(Date:3/27/2021)... ... 25, 2021 , ... The 2021 Virtual Conference on Clinical Trial Supply-Europe ... More and more, clinical trial supply conferences are featuring speakers and forums that ... Asymmetrex’s founder and CEO, James L. Sherley, M.D., Ph.D., presented a talk ...
(Date:3/23/2021)... ... March 23, 2021 , ... G-CON Manufacturing (G-CON), the ... by Matica Biotechnology (Matica Bio), a contract development and manufacturing organization (CDMO) specializing ... the cleanroom build out for its new GMP production facility in College Station, ...
Breaking Biology News(10 mins):
(Date:3/27/2021)... ... March 24, 2021 , ... ... Life Sciences and Healthcare firms of all sizes, adds depth to its team ... specialist. Pardillo, who earned his doctorate in computational chemistry from Florida International University ...
(Date:3/27/2021)... ... March 24, 2021 , ... ABI Wellness, ... and reporting approach designed under CEO Mark Watson, today announced a webinar dedicated ... featuring guest speakers Dr. Cameron Clark, Neuropsychologist and Founder of Sharp Thinking, and ...
(Date:3/27/2021)... ... ... The Xtalks editorial team is pleased to announce the launch of the ... joined by editorial team members Ayesha Rashid, Sydney Perelmutter and Mira Nabulsi to discuss ... including insights from industry experts. , The Xtalks Life Science podcast will feature ...
(Date:3/23/2021)... Conn. (PRWEB) , ... March 23, 2021 , ... ... develops solutions for characterizing microbiome populations down to the strain level, recently unveiled ... applications. , Not all microbes are created equal: some are easy to ...
Breaking Biology Technology:
Cached News: