HOME >> BIOLOGY >> NEWS
Fat fighting undermined by over active eating pacemaker

Researchers at the University of Warwick have for the first time been able to detail how and why specific neurons in the brain control the hunger response. They have revealed a set of pacemaker nerve cells in the brain that appear to underlie the drive to feed which itself feeds on a complex web of signals. The level of complexity they have found is such that the system could be much more at risk of serious repercussions from a single error in how those signals are processed than anyone had previously thought. Any number of a range of errors could lead to over activity of these pacemaker cells and explain why many people find difficulty in eating less.

In the research, published in the May Issue of Nature Neuroscience, Dr David Spanswick and his research team in the University of Warwick's Department of Biological Sciences, looked at a part of the brain called the hypothalamic arcuate nucleus which was known to deal with hunger and satiety signals but how it achieves this is poorly understood. The University of Warwick team have identified very specific neurons that act as feeding "pacemakers".

This specific group of neurons- which they have dubbed the "ARC pacemaker" produce regular bursts of electrical activity. However these cells integrate and process a wide variety of signals indicating the energy needs of the body signals most often transmitted by the use of chemical messengers such as hormones like ghrelin, released from the gut and leptin from fat cells.

The combination of these signals and their integration by the ARC pacemaker is such a finely balanced mechanism that one small error or mutation leading to any inappropriate communication in these pathways could produce a significant untoward affect on human eating or feeding patterns.

The high number of potential ways that this delicately balanced hunger pacemaker can go wrong could explain why many overweight people are unable to address their weight problems by a combinati
'"/>

Contact: Dr. David Spanswick
D.C.Spanswick@warwick.ac.uk
44-0-24-76-574182
University of Warwick
11-May-2004


Page: 1 2

Related biology news :

1. White tea beats green tea in fighting germs
2. Researchers awarded $2 million to create high-tech tools for fighting wildfires
3. Armies of fighting fungi protect chocolate trees
4. Seed dormancy may hold the key to fighting weeds
5. Antibodies critical for fighting West Nile Virus infection
6. OXiGENE, foundation fighting blindness sign research agreement for phase I/II clinical trial
7. Rare disorder provides new insight into fighting infection
8. Cooking sweet corn boosts disease-fighting nutrients
9. New witchweed-fighting method, presented by CIMMYT and Weizmann Institute scientist
10. Tomato packs more cancer-fighting punch
11. Ramoplanin beats antibiotic resistance by fighting the battle on its own terms

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/23/2017)... GENOA, Italy , May 23, 2017  Hunova, the first robotic ... and trunk, has been officially launched in Genoa, Italy ... Europe and the USA . The ... launched on the market by the IIT spin-off Movendo Technology thanks to ... view the Multimedia News Release, please click: ...
(Date:5/6/2017)... 5, 2017 RAM Group , ... new breakthrough in biometric authentication based on a ... properties to perform biometric authentication. These new sensors are ... created by Ram Group and its partners. This sensor ... supply chains and security. Ram Group is a ...
(Date:4/18/2017)... , April 18, 2017  Socionext Inc., a global expert in ... media edge server, the M820, which features the company,s hybrid codec ... provided by Tera Probe, Inc., will be showcased during the upcoming ... NAB show at the Las Vegas Convention ... Click ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... October 11, 2017 , ... ... today it will be hosting a Webinar titled, “Pathology is going digital. Is ... , on digital pathology adoption best practices and how Proscia improves lab economics ...
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... ... Administration (FDA) has granted orphan drug designation to SBT-100, its novel anti-STAT3 (Signal ... the treatment of osteosarcoma. SBT-100 is able to cross the cell membrane and ...
(Date:10/10/2017)... firm Parks Associates announced today that Tom Kerber , ... Meeting , October 11 in Scottsdale, Arizona . Kerber ... smart safety and security products impact the competitive landscape. ... Parks Associates: Smart Home Devices: Main Purchase Driver ... "The residential security market has experienced continued growth, and the introduction ...
(Date:10/9/2017)... ... 2017 , ... The award-winning American Farmer television series will feature 3 Bar ... Tuesdays at 8:30aET on RFD-TV. , With global population estimates nearing ten billion ... continue to feed a growing nation. At the same time, many of our valuable ...
Breaking Biology Technology:
Cached News: