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Federally Sponsored Panel To Look At Data On Plasticizers: Do They Harm Reproduction, Or Children's Development?

The federal government's new reproductive risk evaluation center today announced its first review -- a look at the possible reproductive risks to plastics workers and consumers from seven phthalates found widely in consumer products and the environment. Phthalates are chemical plasticizers used in making flexible vinyl products such as shower curtains, medical devices such as tubing and IV bags, upholstery, raincoats, balls and soft squeeze toys.

The new NTP Center for the Evaluation of Risks to Human Reproduction will assemble a dozen or more scientists with applicable expertise to evaluate the substances in public sessions, according to a center announcement in the Federal Register. The sessions are tentatively planned for August in the Washington, D.C., area.

The center asked scientists to share their latest data on the substances to be reviewed: butyl benzyl phthalate, di(2-ethylhexyl) phthalate, di-isodecyl phthalate, di-isononyl phthalate, di-n-butyl phthalate, di-n-hexyl phthalate, and di-n-octyl phthalate.

The National Institute of Environmental Health Sciences and the National Toxicology Program, which is headquartered at NIEHS, in January announced the creation of the NTP Center for the Evaluation of Risks to Human Reproduction to evaluate risks to human reproduction and child development for regulatory agencies and the public -- and to point to gaps in knowledge that need to be filled by additional research and testing.

"A decline in human sperm counts over recent decades has been reported but not confirmed," officials said in the January announcement, adding that 5 to 10 percent of couples who want children cannot get pregnant and 3 to 5 percent of newborns have major birth defects.

"The panel will look at data to see how likely it may be that phthalates contribute to these reproductive and developmental problems," Michael Shelby, Ph.D., chief of the Laboratory of Toxic
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Contact: Bill Grigg
grigg@niehs.nih.gov
301-402-3378
NIH/National Institute of Environmental Health Sciences
12-Apr-1999


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