Female vulnerability to drugs tied to estrogen, U-M research...( wild female rats run away from the mat...)

wild, female rats run away from the mating male to slow down the pace to their desired level. In the laboratory, female rats will bar press to get away from the male, but most experimenters use a seminatural environment that gives the female a safe place to run away to and hide from the male. In experiments, Becker and colleagues have found that estrogen enhances the behaviors that females engage in to slow male rats down. "So, the effects of estrogen to enhance sexual motivation may underlie the effects of estrogen on drug sensitization and addiction," Becker speculates.

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Contact: Diane Swanbrow
swanbrow@umich.edu
734-647-4416
University of Michigan
14-Nov-2001

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