HOME >> BIOLOGY >> NEWS
Fetal and prepubertal growth both programme cholesterol metabolism in adulthood

Birthweight, subsequent growth, and cholesterol metabolism in children 8-12 years old born preterm 2001;84: 212-17

The body's ability to process cholesterol as an adult is likely to be programmed by size at birth, shows research in Archives of Disease in Childhood. But just as important are the years between 8 and 12.

Birthweight, length of pregnancy, and weight at 18 months were measured in 412 boys and girls, all of whom were light for dates at birth. Blood fats, including indicators of cholesterol production and absorption, were subsequently measured when the children were aged 8 and 12.

Lower birthweight was associated with reduced cholesterol absorption in children born prematurely. Children who had more catching-up to do to achieve normal weight for age were significantly more likely to process cholesterol less efficiently, between the ages of 8 and 12.

The amount of body fat a child carried, rather than overall weight or current height, was associated with increased cholesterol production and lower cholesterol absorption. And that remained true even when the child was within the normal range of fatness, suggesting increasing fatness during childhood can affect the body's subsequent ability to process cholesterol.

The authors suggest that their findings indicate that cholesterol metabolism, and the attendant risk of heart disease in adulthood, are programmed not only during the womb, but also by growth up to puberty.


'"/>

Contact: BMA Press Office
pressoffice@bma.org.uk
44-0-207-383-6254
BMJ Specialty Journals
21-Feb-2001


Page: 1

Related biology news :

1. Fetal lungs provide a signal initiating labor, UT Southwestern researchers find
2. Fetal death, miscarriage linked to genetic mutation
3. CDC MMWR: Fetal Alcohol Syndrome and Cutaneous Anthrax in a Lab Worker
4. Fetal research first in USA
5. Fetal and birth complications increase mental illness risks
6. Functional Arteries Grown From Cells Using Novel System That Simulates Fetal Environment
7. Study Suggests Maternal Stress And Stress Hormones May Influence Fetal Brain Development In Utero
8. Maternal Anxiety May Affect Fetal Development
9. Fetal Surgery For Spina Bifida Still Under Investigation At VUMC
10. Fetal Growth Rate Affects Risk Of Heart Disease
11. Fetal Lead Exposure May Reduce Immunity

Post Your Comments:
(Date:7/23/2014)... Chrysomya megacephala is commonly found in dead bodies ... time of death, referred to as the post mortem ... C. megacephala from Tamil Nadu is provided for ... characterization through generation of DNA barcoding. This study, significant ... Biodiversity Data Journal . , Chrysomya megacephala ...
(Date:7/23/2014)... New Rochelle, NY -- The potential for clinical ... for transplant-based therapeutic strategies has previously been hindered ... the development of tumors. The ability to use ... for the treatment of heart disease, specifically acute ... Stem Cells and Development , a peer-reviewed ...
(Date:7/23/2014)... MINNETONKA, Minn. , July 23, 2014 /PRNewswire/ ... technology company specializing in clinical study management systems, ... West , a proven life sciences industry executive ... named Chief Operating Officer (COO).  Clareece will be ... and sales growth, operational efficiency and quality product/service ...
Breaking Biology News(10 mins):Dead body feeding larvae useful in forensic investigations 2MedNet Appoints Clareece West As Chief Operating Officer 2
(Date:7/23/2014)... July 23, 2014 ... of Trendlines Agtech , announced it has ... Israel,s leading agricultural thermoplastics applications companies. ... Valentis,s technology combines nanocrystalline cellulose (NCC), a biodegradable, ... additional nanoparticles to produce highly improved polymeric films. ...
(Date:7/23/2014)... regulated information -- UCB today announced an important advance ... topline results from the latest Phase 3 study ... evaluate the efficacy and safety of brivaracetam ... to placebo, as adjunctive treatment in adult focal ... despite treatment with one or two concomitant antiepileptic ...
(Date:7/23/2014)... 2014  Sofinnova Ventures, a Menlo Park ... of Sofinnova Venture Partners IX, L.P. at the hard ... initial fund target of $425 million. Sofinnova ... Consistent with recent funds, SVP IX will provide capital ... along with select investments in earlier stage opportunities. Investments ...
(Date:7/23/2014)... 2014 OncLive® is pleased to ... joined its Strategic Alliance Partnership program. , ... UNC Lineberger will have the opportunity to work ... its cutting-edge research initiatives, community-directed cancer prevention programs, ... work with OncLive to educate their peers by ...
Breaking Biology Technology:Valentis Nanotech Signs MOU to Integrate Technology in Thermoplastics Production 2Major advance in UCB pipeline: positive topline Phase 3 results for brivaracetam in epilepsy patients with partial-onset seizures 2Major advance in UCB pipeline: positive topline Phase 3 results for brivaracetam in epilepsy patients with partial-onset seizures 3Major advance in UCB pipeline: positive topline Phase 3 results for brivaracetam in epilepsy patients with partial-onset seizures 4Major advance in UCB pipeline: positive topline Phase 3 results for brivaracetam in epilepsy patients with partial-onset seizures 5Major advance in UCB pipeline: positive topline Phase 3 results for brivaracetam in epilepsy patients with partial-onset seizures 6Major advance in UCB pipeline: positive topline Phase 3 results for brivaracetam in epilepsy patients with partial-onset seizures 7Sofinnova Raises $500 Million Biotech Venture Fund 2OncLive Expands Its Strategic Alliance Partnership Program With the Addition of UNC Lineberger Comprehensive Cancer Center 2OncLive Expands Its Strategic Alliance Partnership Program With the Addition of UNC Lineberger Comprehensive Cancer Center 3
Cached News: