HOME >> BIOLOGY >> NEWS
Fighting diabetes: UD researchers move closer to chip-based control of 'smart,' implantable insulin pumps

injections, Parker says. In clinical trials, meanwhile, some 600 diabetic patients worldwide are using MiniMed Technologies' revolutionary implantable pump, which has not yet been approved by the U.S. Food and Drug Administration (FDA).

Compared to frequent insulin injections, Doyle says, pumps seem to provide patients with improved control of their blood-sugar levels, so that they're less vulnerable to diabetes-related health problems.

Smart pumps on the horizon?

But, existing implantable designs simply deliver a low dose of insulin on a continuous basis, Parker notes. Patients also can self-administer additional insulin before a meal.

"By developing glucose sensors and predictive algorithms for these devices," Parker says, "we hope to dramatically improve and automate the control of blood-sugar levels."

Highly precise control is important because sugar concentrations above the normal level of 70 to 120 milligrams of glucose per deciliter of blood (mg/dl) have been associated with liver damage, blindness and other medical problems. And, cells begin to starve when blood-sugar levels fall too low.

So, UD researchers are working on "a smarter brain for the next generation of implantable insulin pumps," Doyle says. "In the future, our system could fit on a computer chip, processing glucose sensor information, and then translating that data into pump action."

Predicting the body's insulin needs

Traditionally, mathematical commands or algorithms for controlling blood-sugar levels have been "like a thermostat-either on or off," Doyle says. "The classic approach has been a bang-bang type of algorithm," he added. "When sugar levels are high, these systems deliver a dose of insulin. When sugar is low, they turn insulin delivery back down."

Unfortunately, this approach isn't "meal-proof," Doyle says, and it doesn't reflect dramatic variations among individuals. In other words, "These algorithms can't predict and plan ahead for the increase
'"/>

Contact: Ginger Pinholster
gingpin@udel.edu
302-831-6408
University of Delaware
6-Jun-1999


Page: 1 2 3

Related biology news :

1. Fighting Mycobacterium tuberculosis with structural proteomics
2. Fighting fire with fire? Vaccine based on chimp virus shows promise against HIV
3. Fighting the spread of sudden oak death
4. Fighting the battle of the bulge in children
5. Fighting breast cancer at the molecular level
6. Fighting Fungi
7. Fighting skin cancers with computers and technology
8. Trash From Crop-Processing Plant Harvested For Disease-Fighting Agents
9. Studies At Cedars-Sinai Confirm Identity Of An Elusive Receptor In Human Cells -- A Breakthrough In Understanding, Fighting Septic Shock
10. Chemical Contaminants May Inhibit Cancer-Fighting White Blood Cells
11. Radioactive Beads Latest Weapon In Fighting Cancer In Dogs, Cats

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/4/2016)... 4, 2016 The field of Human ... the most popular hubs of the biotechnology industry. ... huge studies of human microbiota, have garnered a ... the microbiome space has literally exploded in terms ... This report focuses on biomedical aspects of research, ...
(Date:2/3/2016)... India , February 3, 2016 ... the new market research report "Automated Fingerprint Identification System ... Search, Latent Search), Application (Banking & Finance, Government, Healthcare, ... published by MarketsandMarkets, the market is expected to be ... CAGR of 21.0% between 2015 and 2020. The transformation ...
(Date:2/3/2016)... 2016 http://www.researchandmarkets.com/research/d8zjcd/emotion_detection ... "Emotion Detection and Recognition Market by ... Software Tools (Facial Expression, Voice Recognition and ... - Global forecast to 2020" report ... http://www.researchandmarkets.com/research/d8zjcd/emotion_detection ) has announced the addition of ...
Breaking Biology News(10 mins):
(Date:2/9/2016)... 2016 This market research report on the ... prospects of the market in terms of revenue (USD ... in the manufacture of microbiology culture media and related ... market snapshot providing the overall information of various market ... section also provides the overall information and data analysis ...
(Date:2/9/2016)... , February 9, 2016 Three-Year ... Enables Children to Take Part in Life-Changing Camp ... new initiative designed to positively affect the lives of children born ... care. --> SHPG ) is announcing a new initiative ... diseases, as well as the future of rare disease care. ...
(Date:2/9/2016)... 9, 2016 DelveInsight,s, ... report provides in depth insights on the ... the Protein-Tyrosine Phosphatase 1B (PTP1B) Inhibitors. The ... various stages of development including Discovery, Pre-clinical, ... and Preregistration. Report covers the product clinical ...
(Date:2/8/2016)... Should antibiotic bone cement products be used ... infection after standard total hip or knee replacement surgery? ... have been fielding a lot lately. "Antibiotic ... --> "Antibiotic Bone Cement: Fighting ... --> While there isn,t a simple answer, ECRI ...
Breaking Biology Technology:
Cached News: