HOME >> BIOLOGY >> NEWS
Fighting diabetes: UD researchers move closer to chip-based control of 'smart,' implantable insulin pumps

d blood-sugar levels that can occur after a diabetic patient eats," he explains.

As a result, he says, patients may experience many hours of very high or low sugar levels before returning to a normal state.

The UD system more precisely controls blood sugar by constantly predicting the patient's need for insulin. Based on a mathematical model of the human glucose-insulin system, the algorithms analyze data from past events to forecast future insulin requirements.

And, because the algorithms are "linear," or simplified to approximate the function of the gut, the pancreas and other portions of body systems, they could be maintained on a tiny computer chip, Doyle says.

His approach, based on "model predictive control with state estimation" (MPCSE) algorithms, effectively reduced peak glucose levels by 44 percent, in computer simulations, compared to algorithms published in scholarly literature.

The system also reduced by 80 percent the "overshoot," or degree to which blood-sugar levels rose above a targeted range of 81 mg/dl, compared to patients with uncontrolled diabetes, Parker says. Small delays in receiving data from glucose sensors didn't seem to impair the performance of the UD system, which demonstrated a settling time of about 4.5 hours.

Doyle predicts that "smart" implantable insulin pumps won't become available to patients for another three to five years, even with FDA approval. But, he says, research presented at the AAMI meeting confirms the viability of this promising new technology.

Someday, he says: "Automatically controlled, implantable insulin delivery systems will no longer be science fiction."


'"/>

Contact: Ginger Pinholster
gingpin@udel.edu
302-831-6408
University of Delaware
6-Jun-1999


Page: 1 2 3

Related biology news :

1. Fighting Mycobacterium tuberculosis with structural proteomics
2. Fighting fire with fire? Vaccine based on chimp virus shows promise against HIV
3. Fighting the spread of sudden oak death
4. Fighting the battle of the bulge in children
5. Fighting breast cancer at the molecular level
6. Fighting Fungi
7. Fighting skin cancers with computers and technology
8. Trash From Crop-Processing Plant Harvested For Disease-Fighting Agents
9. Studies At Cedars-Sinai Confirm Identity Of An Elusive Receptor In Human Cells -- A Breakthrough In Understanding, Fighting Septic Shock
10. Chemical Contaminants May Inhibit Cancer-Fighting White Blood Cells
11. Radioactive Beads Latest Weapon In Fighting Cancer In Dogs, Cats

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/22/2016)... PROVO and SANDY, Utah ... Ontario (NSO), which operates the highest sample volume laboratory ... and Tute Genomics and UNIConnect, leaders in clinical sequencing ... announced the launch of a project to establish the ... panel. NSO has been contracted by ...
(Date:3/15/2016)... 15, 2016 --> ... Transparency Market Research "Digital Door Lock Systems Market - Global ... 2023," the global digital door lock systems market in terms ... and is forecast to grow at a CAGR of 31.8% ... and medium enterprises (MSMEs) across the world and high industrial ...
(Date:3/11/2016)... 11, 2016 http://www.apimages.com ) - --> ... is available at AP Images ( http://www.apimages.com ) - ... used to produce the new refugee identity cards. DERMALOG will be ... CeBIT in Hanover next week.   --> ... be used to produce the new refugee identity cards. DERMALOG will ...
Breaking Biology News(10 mins):
(Date:4/29/2016)... Denver, CO (PRWEB) , ... April 29, 2016 ... ... on addressing the necessary fundamentals to transform technology into a viable company, CereScan’s ... enable growth. Mr. Kelley, a recognized leader and mentor in the Denver ...
(Date:4/29/2016)... ... ... Intelligent Implant Systems announced today that the two-level components for the Revolution™ Spinal System ... These components expand the capabilities of the system and allow Revolution™ to be utilized ... the company has seen significant sales growth in 1Q 2016, and the system is ...
(Date:4/28/2016)... 2016 The report "Cryocooler Market ... Service (Technical Support, Product Repairs & Refurbishment, Preventive Maintenance, ... to 2022", published by MarketsandMarkets, the global market is ... at a CAGR of 7.29% between 2016 and 2022. ... 94 Figures spread through 159 Pages and in-depth TOC ...
(Date:4/28/2016)... ... April 28, 2016 , ... Connecticut Innovations ... growing companies, today announced the launch of VentureClash , a $5 million ... , “VentureClash looks to attract the best early-stage companies here in Connecticut, ...
Breaking Biology Technology:
Cached News: