HOME >> BIOLOGY >> NEWS
Finding the hole in the defenses of cavity-creating microbes

defenses fell; the cell membrane was no longer able to protect against the acid the bacteria churn out.

"These bacteria should not be able to live in the mouth," says Quivey, "but they adapt to the acidic environment and thrive, thanks to the special defenses they use. Not only that, but the acid they produce harms other bacteria, allowing S. mutans to dominate. We're trying to make the human mouth, the only hospitable environment that S. mutans has ever found, inhospitable."

S. mutans is one of hundreds of types of bacteria in the human mouth. When people eat sugary foods, S. mutans eats the sugars, coats the teeth, excretes acids, and forms a pudding-like goo plaque that consists of bacteria, sugars, and other substances all locked together in a matrix that sticks to teeth. As the crowd of bacteria gathers, it becomes tough for saliva, a healthful substance that bathes the teeth in nutrients and fights cavities, to reach and cleanse the teeth.

"Within an hour after you eat, you can run your tongue over your teeth and feel a sort of film. That's plaque really, a community of bacteria making themselves comfortable for a long-term stay in your mouth. It can really get disgusting in there," says Quivey."

With S. mutans comfortably lodged along our tooth surfaces, the pH in our mouths quickly plummets, becoming 100 to 1,000 times more acidic than normal. Without frequent brushing and flossing, the assault on our teeth results in cavities quickly.

Like S. mutans, other bacteria have the ability to change their cell membranes to cope with harsh conditions. E. coli bacteria happily ensconced in red meat perform a similar trick as they travel through the human digestive system. Another harmful bacterium, Listeria, changes its membrane properties to allow it to live even in the cool temperatures of the refrigerator.

Matching the bacteria's abilities, however, are various human strategies to kill the microbes. Many cu
'"/>

Contact: Tom Rickey
trickey@admin.rochester.edu
585-275-7954
University of Rochester Medical Center
25-Jun-2004


Page: 1 2 3

Related biology news :

1. Findings suggest need for new view of p53 cancer proteins interaction with DNA
2. Findings redefine mechanism of action of RNA helicase enzymes
3. Findings of novel nanoproperties in selenium produced by bacteria open new area of exploration
4. Finding may help eczema sufferers tolerate smallpox vaccine
5. Findings could aid efforts to harness nature for making drugs
6. Findings offer clue to how molecule can both stimulate, suppress cell growth
7. Findings offer further understanding about growth and development in young male gymnasts
8. Findings in frog oocytes may help study of chromosome physiology
9. Finding dirty bombs and other radiation threats
10. Finding life away from Earth will be tough task, says noted paleontologist
11. Finding a Holy Grail: simulated and experimental protein folding compares nicely

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Finding the hole the defenses cavity creating microbes

(Date:12/17/2014)... 15, 2014  HITLAB SM announced today its completion ... its adherence to current U.S. Food and Drug Administration ... smart device and smart phone application trials utilizing the ... "HITLAB is determined to improve global healthcare access, ...
(Date:12/17/2014)... 2014  Automation is fundamentally transforming the travel experience and ... Over the past decade, ePassports, biometric readers, and secure ... through border control via eGates and Automated Passport Control ... and land borders across the globe. ...
(Date:12/11/2014)... Markets , http://photos.prnewswire.com/prnh/20130307/600769 ... addition of the "Biometrics Market in India 2015-2019" ... major trend emerging in this market is the adoption ... than one characteristic of an individual for verification and ...
Breaking Biology News(10 mins):HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
(Date:1/23/2015)... Portal Solutions , a technology consulting ... Microsoft Office 365 and SharePoint platforms , today announces its ... being one of the region’s fastest-growing mid-sized companies based on ... , “To be recognized a second year in a row ...
(Date:1/22/2015)... GEA Niro Soavi the leader in ... the PandaPLUS 2000, which is ideal for new applications ... cell disruption . This compact laboratory homogenizer is the ... food, food additives and ingredients as well as for ...
(Date:1/22/2015)... Johnston, RI (PRWEB) January 22, 2015 ... State , The growing team of brand-neutral, independent consultants, ... CIO Philip Rogers explained that over the years, his ... including , Moroso, Town of Plainfield, as well as ...
(Date:1/22/2015)... 22, 2015 Dr. Greg Leyer of UAS ... Scripps Natural Supplements Pre-Conference seminar on probiotics in San Diego, ... annual continuing education conference for health care professionals. This year’s ... topic of probiotics in health. Dr. Leyer spoke about the ...
Breaking Biology Technology:Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 2Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 3GEA Niro Soavi Announces the PandaPLUS 2000 Homogenizer for Processing New Applications for Nanoemulsions and Cell Disruption 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 2
Cached News: