HOME >> BIOLOGY >> NEWS
Finding the hole in the defenses of cavity-creating microbes

defenses fell; the cell membrane was no longer able to protect against the acid the bacteria churn out.

"These bacteria should not be able to live in the mouth," says Quivey, "but they adapt to the acidic environment and thrive, thanks to the special defenses they use. Not only that, but the acid they produce harms other bacteria, allowing S. mutans to dominate. We're trying to make the human mouth, the only hospitable environment that S. mutans has ever found, inhospitable."

S. mutans is one of hundreds of types of bacteria in the human mouth. When people eat sugary foods, S. mutans eats the sugars, coats the teeth, excretes acids, and forms a pudding-like goo plaque that consists of bacteria, sugars, and other substances all locked together in a matrix that sticks to teeth. As the crowd of bacteria gathers, it becomes tough for saliva, a healthful substance that bathes the teeth in nutrients and fights cavities, to reach and cleanse the teeth.

"Within an hour after you eat, you can run your tongue over your teeth and feel a sort of film. That's plaque really, a community of bacteria making themselves comfortable for a long-term stay in your mouth. It can really get disgusting in there," says Quivey."

With S. mutans comfortably lodged along our tooth surfaces, the pH in our mouths quickly plummets, becoming 100 to 1,000 times more acidic than normal. Without frequent brushing and flossing, the assault on our teeth results in cavities quickly.

Like S. mutans, other bacteria have the ability to change their cell membranes to cope with harsh conditions. E. coli bacteria happily ensconced in red meat perform a similar trick as they travel through the human digestive system. Another harmful bacterium, Listeria, changes its membrane properties to allow it to live even in the cool temperatures of the refrigerator.

Matching the bacteria's abilities, however, are various human strategies to kill the microbes. Many cu
'"/>

Contact: Tom Rickey
trickey@admin.rochester.edu
585-275-7954
University of Rochester Medical Center
25-Jun-2004


Page: 1 2 3

Related biology news :

1. Findings suggest need for new view of p53 cancer proteins interaction with DNA
2. Findings redefine mechanism of action of RNA helicase enzymes
3. Findings of novel nanoproperties in selenium produced by bacteria open new area of exploration
4. Finding may help eczema sufferers tolerate smallpox vaccine
5. Findings could aid efforts to harness nature for making drugs
6. Findings offer clue to how molecule can both stimulate, suppress cell growth
7. Findings offer further understanding about growth and development in young male gymnasts
8. Findings in frog oocytes may help study of chromosome physiology
9. Finding dirty bombs and other radiation threats
10. Finding life away from Earth will be tough task, says noted paleontologist
11. Finding a Holy Grail: simulated and experimental protein folding compares nicely

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Finding the hole the defenses cavity creating microbes

(Date:3/11/2015)... March 11, 2015   The Sync Project™ ... to scientifically measure and harness music to improve ... biometrics and objective measurements of physiology, enabling the ... scale in large populations. It is designed for ... clinicians perform rigorous studies and accelerate the discovery ...
(Date:3/10/2015)... 2015   Tute Genomics , pioneer in affordable, ... next-generation sequencing company PrimBio Research Institute to ... gene panel interpretation. PrimBio, a certified Life ... current technologies to support the work of experts on ... two types of exome sequencing services: 1) Targeted Exome ...
(Date:3/4/2015)... 04, 2015 Research and Markets ... the "Global Biometrics Market Forecast and Opportunities, ... The market for biometric authentication systems is projected ... till 2020 The driving forces for ... needs, government projects and constant development in technology. ...
Breaking Biology News(10 mins):Introducing The Sync Project, a Global Collaboration Harnessing the Scientific Potential of Music for Health 2Introducing The Sync Project, a Global Collaboration Harnessing the Scientific Potential of Music for Health 3PrimBio Research Selects Tute as Whole Exome Analysis Provider, Creating Integrated, End-to-End Solution for Next-Generation Sequencing & Data Analysis 2PrimBio Research Selects Tute as Whole Exome Analysis Provider, Creating Integrated, End-to-End Solution for Next-Generation Sequencing & Data Analysis 3Global Biometrics Market Forecast and Opportunities, 2020 2Global Biometrics Market Forecast and Opportunities, 2020 3
(Date:3/27/2015)... York (PRWEB) March 27, 2015 Governor ... 2015 application period for 43North - the world’s largest ... including a grand prize of $1 million, six $500,000 ... from around the world to compete for prizes that ... enterprises in the Western New York region. , ...
(Date:3/26/2015)... , March 26, 2015 /PRNewswire/ - SQI Diagnostics ... announced that after dealing with certain matters, including the ... shareholders held on March 26, 2015 (the "Meeting") was ... April 8, 2015 at 11:00 a.m. ( Toronto ... has been changed from that previous disclosed. The Meeting ...
(Date:3/26/2015)... Massachusetts and CINCINNATI ... Shire plc (LSE: SHP, NASDAQ: SHPG ) ... a three-year, broad research collaboration for rare diseases. The ... develop novel therapies to treat rare diseases with ... commercialization capabilities with Cincinnati Children,s research expertise. As ...
(Date:3/26/2015)... 2015 ReliantHeart, Inc., an innovative supplier ... supplier of precision transit-time flow measurement solutions, are collaborating ... the efficiency of the HeartAssist5® Left Ventricular ... experience greater mobility and peace of mind. , ... board, will draw 1/6th of the power required by ...
Breaking Biology Technology:Governor Andrew M. Cuomo Anounces Launch of Year Two of World's Largest Business Idea Competition and Opening of New Incubator Space in Buffalo, New York 2Governor Andrew M. Cuomo Anounces Launch of Year Two of World's Largest Business Idea Competition and Opening of New Incubator Space in Buffalo, New York 3Governor Andrew M. Cuomo Anounces Launch of Year Two of World's Largest Business Idea Competition and Opening of New Incubator Space in Buffalo, New York 4Governor Andrew M. Cuomo Anounces Launch of Year Two of World's Largest Business Idea Competition and Opening of New Incubator Space in Buffalo, New York 5SQI Diagnostics Inc. Announces Adjournment of Meeting 2Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 2Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 3Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 4Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 5LVAD patients to have greater mobility and peace of mind through Transonic and ReliantHeart’s True Flow collaboration for the HeartAssist5® 2LVAD patients to have greater mobility and peace of mind through Transonic and ReliantHeart’s True Flow collaboration for the HeartAssist5® 3
Cached News: