HOME >> BIOLOGY >> NEWS
First awards made in NIH effort to understand how genes affect people's responses to medicines

Diet, environment, and lifestyle can all influence how a person responds to medicines--but another key factor is genes. The National Institute of General Medical Sciences (NIGMS) and other components of the National Institutes of Health (NIH) are sponsoring a nationwide research effort to understand how a person's genetic make-up determines the way a medicine works in his or her body, as well as what side effects the person might be prone to developing.

This so-called "pharmacogenetics" research focuses on linking the body's response to medicines with variations in particular genes. Many of these variations are expected to be "single-letter" differences, known as single-nucleotide polymorphisms or "SNPs." However, other genetic variations affecting how a person reacts to a specific medicine could be missing genes, or even extra genes. Through these types of studies, researchers ultimately hope to develop drug dosing into a much more predictive science.

"The outcome of pharmacogenetics research has the potential to improve the health of all Americans, by making the medicines of today and tomorrow safer and more effective for everyone," said Dr. Rochelle Long, a pharmacologist at NIGMS who spearheaded the pharmacogenetics initiative.

The trans-NIH effort is designed to forge an interactive research network of investigators who will store data in a shared information library freely accessible to the scientific community. To protect participants' privacy, names and other identifying information will not be stored in this library.

In addition to NIGMS, the other NIH components funding the pharmacogenetics research network awards are the National Cancer Institute (NCI); the National Heart, Lung, and Blood Institute (NHLBI); the National Human Genome Research Institute (NHGRI); the National Institute of Environmental Health Sciences (NIEHS); and the National Library of Medicine (NLM).

Nine awards, totaling $12.8 million for the first
'"/>

Contact: Alison Davis
davisa@nigms.nih.gov
301-496-7301
NIH/National Institute of General Medical Sciences
3-Apr-2000


Page: 1 2 3

Related biology news :

1. First glimpse of DNA binding to viral enzyme
2. First clinical study of new pediatric croup vaccine shows safety, tolerability in adults
3. 2nd media alert First Scientific Conference on Childhood Leukaemia
4. First International Scientific Conference on Childhood Leukaemia
5. First ever standards linking climate change, biodiversity and poverty seek global peer review
6. First genetic comparison of purebred domestic dogs produces surprises
7. First time in the U.S.: Saint Louis University tests third-generation vaccine against smallpox
8. First target for childhood malaria vaccine
9. First study of resveratrol dietary supplement finds effect on breast and prostate cancers unlikely
10. First flavors form a lasting impression
11. STN International launches Derwent World Patents Index First View

Post Your Comments:
(Date:10/18/2014)... stress and stress-related psychiatric disorders are associated ... the molecular mechanisms underlying this relation are ... the development of targeted preventive strategies and ... diseases. This work is presented at the ... Now an international group of researchers from ...
(Date:10/18/2014)... In a sample of patients with undiagnosed, suspected genetic ... associated with a higher molecular diagnostic yield than traditional ... JAMA . The study is being released to ... meeting. , Exome sequencing, which sequences the protein­coding region ... genetic material present in a cell or organism), has ...
(Date:10/17/2014)... available in German . ... every day in order to reproduce? And why are there ... of the latest issue of the research journal Molecular ... biologist Steven Ramm from Bielefeld University Bielefeld has compiled this ... unusual for a female to copulate with several males in ...
Breaking Biology News(10 mins):Researchers find why depression and aging linked to increased disease risk 2Study examines type of exome sequencing and molecular diagnostic yield 2Study examines type of exome sequencing and molecular diagnostic yield 3Sperm wars 2
(Date:10/19/2014)... The Asian Orthopedic braces and support systems report defines and ... of revenue. The Orthopedic braces and support systems market in ... 2018, at a developing CAGR of 4.4% from 2013 to ... braces and support systems market, to get an idea of ... the segmentation of orthopedic braces and support systems market in ...
(Date:10/18/2014)... The report "1,6-Hexanediol Market by Application ... 2019", analyzes the global market on the basis ... industry details such as the key drivers, current ... , Browse 81 Market Data Tables and 29 ... on “1,6-Hexanediol Market by Application and by Geography ...
(Date:10/18/2014)... (PRWEB) October 18, 2014 The ... rate in the five years to 2014. The industry's ... renewable energy tax credits that encouraged the use of ... renewable portfolio standards (RPSs), which require local utilities to ... their total energy portfolio. Increased campaigning for green technology ...
(Date:10/17/2014)... Alice,s journey through the looking-glass to Wonderland, mirrors in ... unexpected ways, including a new class of mirror that ... in The Optical Society,s (OSA) new high-impact journal ... first time, a new type of mirror that forgoes ... light by using an unusual magnetic property of a ...
Breaking Biology Technology:The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 2The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 3The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 41,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 21,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 31,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 41,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 5Biomass Power in the US Industry Market Research Report from IBISWorld Has Been Updated 2Biomass Power in the US Industry Market Research Report from IBISWorld Has Been Updated 3Magnetic mirrors enable new technologies by reflecting light in uncanny ways 2Magnetic mirrors enable new technologies by reflecting light in uncanny ways 3Magnetic mirrors enable new technologies by reflecting light in uncanny ways 4
Cached News: