HOME >> BIOLOGY >> NEWS
First study of resveratrol dietary supplement finds effect on breast and prostate cancers unlikely

The first rigorous study of the dietary supplement resveratrol found that oral dietary supplements of resveratrol are unlikely to have any effect on breast and prostate cancer.

Dr. Thomas Walle, Medical University of South Carolina, presented the results at Experimental Biology 2004, as part of the scientific sessions of the American Society of Pharmacology and Experimental Therapeutics.

Resveratrol, a plant antioxidant found in abundance in grapes, wine, and peanuts, is widely sold as a dietary supplement with claims of numerous beneficial health effects. These range from extending life spans to preventing heart disease and cancer. However, these positive health effects have mainly been shown in cultured cells, and it has been unclear if resveratrol can reach the circulating blood in sufficient amounts to have therapeutic effects.

In the study by Dr. Walle and research associate Kristina Walle, C-14-Tagged resveratrol was administered both by mouth and intravenously to healthy volunteers. The researchers found that resveratrol (25-mg doses) is very well absorbed after oral dosing with most of the dose appearing in the urine in the first 12 hours. However, the urine contained resveratrol only as sulfate and glucuronic acid conjugates, none as the free, presumably active, form.

Likewise, the only blood samples containing free resveratrol were those drawn within 30 minutes after the intravenous injection. No free resveratrol was present in blood samples drawn after oral doses.

Based on this study's findings, Dr. Walle ways it would seem highly unlikely that resveratrol per se can have any effect on cardiovascular disease or cancer of such organs as the breast or prostate gland when consumed in the diet or as a dietary supplement.

However, he adds, it is still possible that orally administered resveratrol can prevent cancers along the aerodigestive tract. It is also possible that a resveratrol sulfate conjugate detected
'"/>

Contact: Sarah Goodwin
eb4press@bellsouth.net
770-270-0989
Federation of American Societies for Experimental Biology
19-Apr-2004


Page: 1 2

Related biology news :

1. First glimpse of DNA binding to viral enzyme
2. First clinical study of new pediatric croup vaccine shows safety, tolerability in adults
3. 2nd media alert First Scientific Conference on Childhood Leukaemia
4. First International Scientific Conference on Childhood Leukaemia
5. First ever standards linking climate change, biodiversity and poverty seek global peer review
6. First genetic comparison of purebred domestic dogs produces surprises
7. First time in the U.S.: Saint Louis University tests third-generation vaccine against smallpox
8. First target for childhood malaria vaccine
9. First flavors form a lasting impression
10. STN International launches Derwent World Patents Index First View
11. First DFG research conference in the USA

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/22/2020)... ... July 21, 2020 , ... USDM Life Sciences ... compliance, announces a new solution to manage regulated workloads on Microsoft Azure. , ... technology stack complies with FDA and global regulations. USDM's new managed service for ...
(Date:7/4/2020)... ... July 03, 2020 , ... Aesthetics ... recognition and multiple awards for not only the products and treatments developed, but ... and Vivace® Microneedle RF. All the brands built by ABM have received several ...
(Date:6/28/2020)... ... June 25, 2020 , ... ... biopharmaceutical R&D, today announced that it has entered into a multi-year contract ... (Multiclonics®), to support their translational and clinical research strategy to discover and ...
Breaking Biology News(10 mins):
(Date:8/12/2020)... ... August 11, 2020 , ... The FSHD ... Facioscapulohumeral Muscular Dystrophy Clinical Trial Research Network (FSHD CTRN), with consideration ... is a consortium of academic research centers in the United States and Europe ...
(Date:8/3/2020)... ... August 03, 2020 , ... ERT, ... President and CEO has been named one of the 100 most inspiring individuals ... PharmaVoice 100 honorees are selected based on how they have inspired their colleagues ...
(Date:7/31/2020)... ... 2020 , ... Diversified Technologies, Inc. has introduced a full ... drive Klystrons, TWTs, IOTs, and magnetrons. , DTI Radar Transmitter Systems ... push-pull configuration; yielding fast fall time for a capacitive load. These all solid-state ...
(Date:7/31/2020)... ... 29, 2020 , ... The SDX® Respiratory Gating System ... has reached its 20th anniversary of worldwide use. Introduced in the US over ... including University of Pennsylvania, University of Michigan, University of Maryland, University of California ...
Breaking Biology Technology:
Cached News: