HOME >> BIOLOGY >> NEWS
First study of resveratrol dietary supplement finds effect on breast and prostate cancers unlikely

The first rigorous study of the dietary supplement resveratrol found that oral dietary supplements of resveratrol are unlikely to have any effect on breast and prostate cancer.

Dr. Thomas Walle, Medical University of South Carolina, presented the results at Experimental Biology 2004, as part of the scientific sessions of the American Society of Pharmacology and Experimental Therapeutics.

Resveratrol, a plant antioxidant found in abundance in grapes, wine, and peanuts, is widely sold as a dietary supplement with claims of numerous beneficial health effects. These range from extending life spans to preventing heart disease and cancer. However, these positive health effects have mainly been shown in cultured cells, and it has been unclear if resveratrol can reach the circulating blood in sufficient amounts to have therapeutic effects.

In the study by Dr. Walle and research associate Kristina Walle, C-14-Tagged resveratrol was administered both by mouth and intravenously to healthy volunteers. The researchers found that resveratrol (25-mg doses) is very well absorbed after oral dosing with most of the dose appearing in the urine in the first 12 hours. However, the urine contained resveratrol only as sulfate and glucuronic acid conjugates, none as the free, presumably active, form.

Likewise, the only blood samples containing free resveratrol were those drawn within 30 minutes after the intravenous injection. No free resveratrol was present in blood samples drawn after oral doses.

Based on this study's findings, Dr. Walle ways it would seem highly unlikely that resveratrol per se can have any effect on cardiovascular disease or cancer of such organs as the breast or prostate gland when consumed in the diet or as a dietary supplement.

However, he adds, it is still possible that orally administered resveratrol can prevent cancers along the aerodigestive tract. It is also possible that a resveratrol sulfate conjugate detected
'"/>

Contact: Sarah Goodwin
eb4press@bellsouth.net
770-270-0989
Federation of American Societies for Experimental Biology
19-Apr-2004


Page: 1 2

Related biology news :

1. First glimpse of DNA binding to viral enzyme
2. First clinical study of new pediatric croup vaccine shows safety, tolerability in adults
3. 2nd media alert First Scientific Conference on Childhood Leukaemia
4. First International Scientific Conference on Childhood Leukaemia
5. First ever standards linking climate change, biodiversity and poverty seek global peer review
6. First genetic comparison of purebred domestic dogs produces surprises
7. First time in the U.S.: Saint Louis University tests third-generation vaccine against smallpox
8. First target for childhood malaria vaccine
9. First flavors form a lasting impression
10. STN International launches Derwent World Patents Index First View
11. First DFG research conference in the USA

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/30/2017)... ARLINGTON, Va. , June 30, 2017 /PRNewswire-USNewswire/ ... a leading developer and supplier of face and ... the ATA Featured Product provider program. ... created an innovative way to monitor a driver,s ... benefit greatly from being able to detect fatigue ...
(Date:5/23/2017)... , May 23, 2017  Hunova, the first robotic gym for the ... been officially launched in Genoa, Italy . The first ... and the USA . The technology was developed ... market by the IIT spin-off Movendo Technology thanks to a 10 million ... News Release, please click: ...
(Date:5/6/2017)... RAM Group , Singaporean based ... in biometric authentication based on a novel  ... to perform biometric authentication. These new sensors are based on ... Ram Group and its partners. This sensor will have ... and security. Ram Group is a next generation ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... States multicenter, prospective clinical study that demonstrates the accuracy of the FebriDx® ... identifying clinically significant acute bacterial and viral respiratory tract infections by testing ...
(Date:10/12/2017)... ... 12, 2017 , ... AMRI, a global contract research, development ... patient outcomes and quality of life, will now be offering its impurity solutions ... new regulatory requirements for all new drug products, including the finalization of ICH ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... President Andi Purple announced Dr. Suneel I. Sheikh, the co-founder, CEO and chief ... ), Inc. has been selected for membership in ARCS Alumni Hall of ...
(Date:10/11/2017)... ... 11, 2017 , ... Personal eye wash is a basic first aid supply for any work ... which eye do you rinse first if a dangerous substance enters both eyes? It’s one ... with its unique dual eye piece. , “Whether its dirt and debris, or an ...
Breaking Biology Technology:
Cached News: