First study to watch brain patterns when...( raumatic stress disorder (PTSD) underwe...)

raumatic stress disorder (PTSD) underwent fMRI scanning, while they engaged in tasks: (i) that involve speculation on another's intention, (ii) that invoke empathy and (iii) involve making judgments of actions' forgivability; each versus 'baseline' social reasoning judgments. A post-therapy fMRI scan followed a course of cognitive behavioral therapy with a forgiveness component. Results: Post-therapy, we found increased activation in brain regions predicted on the basis of foregoing work in healthy controls. These included significant left middle temporal gyrus activation in post-therapy response to empathy judgments and posterior cingulate gyrus activation in post-therapy response to forgivability judgments.

Conclusions: Empathic and forgivability judgments activate specific regions of the human brain, which we propose contribute to social cohesion. The activation in these regions changed with symptom resolution in PTSD.

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Contact: Vicki Robb
vicki@jvrobb.com
703-329-3356
John Templeton Foundation
8-Oct-2003

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