Fluid forces within the body help invasiv...( paper people have assumed that E.coli...)

"We need to know how bacterial adhesion is altered by shear," says another author, Dr. Viola Vogel, director of the University of Washington's Center for Nanotechnology in the Department of Bioengineering. "The most amazing part of this is that conventional wisdom says that bacteria have a more difficult time adhering to surfaces when they are subjected to shear force whether the bacteria are in the intestines, in the urinary tract or in biomedical implants. This paper explains how bacteria firmly adhere to surfaces under shear flow, which is remarkable."

Other authors of the paper include Wendy E. Thomas, of the UW Department of Bioengineering, Dr. Elena Trintchina of the Department of Microbiology and Manu Forero of the Department of Physics.

"This is a fairly startling concept," says Dr. Harry L.T. Mobley, professor of microbiology and immunology at the University of Maryland School of Medicine. He is not an author of the paper. "This describes a protein that sticks to things. Usually, we think of a protein either sticking to something or not sticking to something. Here we see a protein binding tighter when it is trying to be sheared off. That opens the door to further investigation."

Presently, most research operates on the assumption that shear stress reduces the lifetime of a receptor bond. However, the paper in C
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