HOME >> BIOLOGY >> NEWS
Folding@home scientists report first distributed computing success

it takes the average computer one day just to do a one-nanosecond [billionth-of-a-second] folding simulation."

Simulating protein folding is often considered a "holy grail" of computational biology, he added. "This is an area of hot competition that includes a number of heavy weights, such as IBM's $100-million, million-processor Blue Gene supercomputer project."

Folding@home

Two years ago, Pande launched Folding@home a distributed computing project that so far has enlisted the aid of more than 200,000 PC owners, whose screensavers are dedicated to simulating the protein-folding process.

The Stanford project operates on principles similar to earlier projects, such as SETI@home, which allows anyone with an Internet connection to search for intelligent life in the universe by downloading special data-analysis software. When a SETI@home screensaver is activated, the PC begins processing packets of radio telescope data. Completed packets are sent back to a central computer, and new ones are assigned automatically.

For the Nature study, Pande and Snow a biophysics graduate student asked volunteer PCs to resolve the folding dynamics of two mutant forms of a tiny protein called BBA5. Each computer was assigned a specific simulation pattern based on its speed.

With 30,000 computers at their disposal, Pande and Snow were able to perform 32,500 folding simulations and accumulate 700 microseconds of folding data. These simulations tested the folding rate of the protein on a 5-, 10- and 20-nanosecond timescale under different temperatures. Using these data, the scientists were able to predict the folding rate and trajectory of the "average" molecule.

Experimental verification

To confirm their predictions, the Stanford team asked Gruebele and Nguyen to conduct "laser temperature-jump experiments" at their Illinois lab. In this technique, an unfolded protein is pulsed with a laser, which heats the molecule just en
'"/>

Contact: Mark Shwartz
mshwartz@stanford.edu
650-723-9296
Stanford University
21-Oct-2002


Page: 1 2 3

Related biology news :

1. DNA lends scientists a hand, revealing new chemical reactions
2. Conference at UH opens doors for new scientists, engineers
3. Wisconsin scientists develop quick botox test
4. UCI scientists successfully target key HIV protein; breakthrough may lead to new drug therapies
5. Alaska scientists find Arctic tundra yields surprising carbon loss
6. UAF scientists discover new marine habitat in Alaska
7. Information system to help scientists analyze mechanisms of social behavior
8. Zoonotic diseases - European scientists unite to fight diseases
9. Israeli scientists reveal the plan of a key cellular machine
10. Study by Israeli scientists provides insight on DNA code
11. Computer scientists at UH developing nurturing computers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/24/2017)... 2017 Janice Kephart , former ... Strategy Partners, LLP (IdSP) , today issues the ... Trump,s March 6, 2017 Executive Order: Protecting ... can be instilled with greater confidence, enabling the ... refugee applications are suspended by until at least ...
(Date:4/13/2017)... According to a new market research report "Consumer ... Administration, and Authorization), Service, Authentication Type, Deployment Mode, Vertical, and Region - ... to grow from USD 14.30 Billion in 2017 to USD 31.75 Billion ... ... MarketsandMarkets Logo ...
(Date:4/6/2017)... LONDON , April 6, 2017 ... Control, RFID, ANPR, Document Readers, by End-Use (Transportation & ... Energy Facility, Oil, Gas & Fossil Generation Facility, Nuclear ... Healthcare, Educational, Other) Are you looking for ... Authentication sector? ...
Breaking Biology News(10 mins):
(Date:6/27/2017)... (PRWEB) , ... June 27, 2017 , ... ... Certification Program (ESTCP), powder activated carbon (PAC)-based materials do not have negative short- ... community at a site contaminated with polychlorinated biphenyls (PCBs) located at the Puget ...
(Date:6/26/2017)... Milwaukee, WI (PRWEB) , ... June 26, 2017 , ... ... today in role of Sales Director, focused on leading new business development and ensuring ... 10 years of experience in the food ingredient industry in technical, marketing and sales ...
(Date:6/23/2017)... ... June 23, 2017 , ... RURO, Inc., a ... of LimitLIS®, its rapidly growing Laboratory Information System. , LimitLIS® version 3 is ... integrity, and provide more customization options. Each of these has been “under the ...
(Date:6/22/2017)... ... June 21, 2017 , ... ... top executive talent in the life sciences industry, today announces a strategic partnership ... The partnership takes full advantage of Beaker’s expertise in executive recruitment solutions, providing ...
Breaking Biology Technology:
Cached News: