HOME >> BIOLOGY >> NEWS
Folic acid may have no immediate impact on Down Syndrome

University of Toronto researchers have found that fortifying foods with folic acid may not reduce the incidence of Down Syndrome. But they suggest we may to need to wait another 20 years or so for the next generation of women to give birth before the real answer is known.

Folic acid has been shown previously to dramatically decrease the incidence of neural tube defects (e.g. spina bifida) in newborns. Dr. Joel Ray, of the Departments of Medicine at U of T and St. Michael's Hospital, and co-researchers decided to examine the prevalence of Trisomy 21 (commonly known as Down Syndrome) following the introduction of folic acid fortification into most Canadian cereal grains by 1998. They examined prenatal and postnatal incidence rates of Trisomy 21 in Ontario, screening nearly 219,000 women prior to fortification and 118,000 women afterward. They found virtually no decline in the incidence of Trisomy 21 in relation to fortification.

However, Ray explains that folic acid and vitamin B12 are essential for the proper development of genes, which lie in chromosomes and are copied as cells divide. He says it's possible that part of the reason they saw no impact of folic acid fortification on Trisomy 21 rates is that the amount of folic acid intake was not high enough. But, he adds, another possibility may be that Trisomy 21 originates even before a woman is born.

"A woman's eggs are formed when she herself is a fetus in her mother's womb," says Ray. "So while taking folic acid may have no impact on the eggs of a woman now to prevent Trisomy 21, it may modify the eggs of her daughter to reduce the risk when she has her own child."

This research, published in the July 30 issue of the American Journal of Medical Genetics Part A, was supported by the Ontario Ministry of Health and Long-Term Care.


'"/>

Contact: Janet Wong
jf.wong@utoronto.ca
416-978-5949
University of Toronto
31-Jul-2003


Page: 1

Related biology news :

1. Folic acid vitamin use by women reaches all-time high, March of Dimes survey finds
2. Folic acid-iron supplements reduce risk of low birth weight
3. Folic acid supplements not linked to multiple births
4. Folic acid supplements and fortified breakfast cereals can reduce homocysteine levels and ischemic heart disease risk
5. American Heart Association Comment: The Effect Of Folic Acid Fortification On Plasma Folate And Total Homocysteine Concentrations
6. Folic Acid Lowers Risk Of Cardiovascular Disease
7. Americans Urged To Consume More Folic Acid
8. New Analytical Methods Indicate Higher Folic Acid Concentration In Beans And Peas
9. Folic Acid Fortification Effective In Cereal Grains
10. Ocean report calls for the immediate creation of marine reserves throughout the United States
11. AAAS urges immediate public release of sources of embryonic stem cell lines

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/14/2017)... (NYSE: IBM ) is introducing several innovative partner startups ... collaboration between startups and global businesses, taking place in ... nine startups will showcase the solutions they have built with ... France is one of the ... percent increase in the number of startups created between 2012 ...
(Date:5/16/2017)... 16, 2017   Bridge Patient Portal , ... MD EMR Systems , an electronic medical ... GE, have established a partnership to build an ... the GE Centricity™ products, including Centricity Practice Solution ... These new integrations will allow healthcare delivery ...
(Date:4/19/2017)... New York , April 19, 2017 ... competitive, as its vendor landscape is marked by the ... the market is however held by five major players ... Safran. Together these companies accounted for nearly 61% of ... of the leading companies in the global military biometrics ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... platform specifically designed for life science researchers to analyze and interpret datasets, ... Franklin, who made a major contribution to the discovery of the double-helix ...
(Date:10/11/2017)... ... ... Personal eye wash is a basic first aid supply for any work environment, but most ... you rinse first if a dangerous substance enters both eyes? It’s one less decision, and ... unique dual eye piece. , “Whether its dirt and debris, or an acid or alkali, ...
(Date:10/11/2017)... , Oct. 11, 2017  VMS BioMarketing, a leading ... a nationwide oncology Clinical Nurse Educator (CNE) network, which will ... need for communication among health care professionals to enhance the ... nurses, office staff, and other health care professionals to help ... breast cancer. ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... implantation and pregnancy rates in frozen and fresh in vitro fertilization (IVF) ... and maternal age to IVF success. , After comparing the results from the ...
Breaking Biology Technology:
Cached News: