HOME >> BIOLOGY >> NEWS
Fred Hutchinson Cancer Research Center, University of Washington join in national effort to study health impact of toxic substances

fessor of environmental health, UW.)

Project 3: This project aims to develop tests for toxic exposure and stress responses using liver cells cultured in the laboratory. Because the liver processes nearly all chemicals that enter the body, the expression of genes in liver cells could predict how a given exposure would affect one's health. To see if their cell-culture systems accurately model the toxic effects of chemical exposures, the researchers will compare the results of tests using cultured cells to those using rodents. One of their ultimate goals is to develop laboratory tests that can replace animal testing. (Project leader: Curtis Omiecinski, Ph.D., professor of environmental health, UW.)

Project 4: This project will use DNA-microarray technology to map and identify genes that influence susceptibility to environmental toxins that cause breast cancer. Relatively few women diagnosed with breast cancer - between 5 percent and 10 percent - carry BRCA1 and BRCA2, the so-called "breast-cancer genes" that have been linked to an inherited form of the disease. However, up to half of all women are believed to carry genetic mutations that may make them susceptible to various environmental exposures linked with breast-cancer growth. Researchers hope that by identifying such genes in rats - and ultimately, humans - they'll better understand how to identify sensitivity to environmental breast-cancer risk factors in the majority of women. (Project leader: Helmut Zarbl, Ph.D., member of the Hutchinson Center's Human Biology and Public Health Sciences divisions and principal investigator of the Hutchinson Center/UW Toxicogenomics Consortium.) Each research project is supported by an infrastructure of technology cores that will provide a range of materials and services. A tissue-acquisition core, directed by UW pathology professor Peter Rabinovitch, M.D., Ph.D., will provide access to genetically defined tissues and cell cultures. A DNA-expression array core, led
'"/>

Contact: Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center
6-Nov-2001


Page: 1 2 3 4 5

Related biology news :

1. Intel and Fred Hutchinson to explore the use of nanotechnology tools for early disease detection
2. American Association for Cancer Research honors Fred Hutchinson Cancer Research Center investigator
3. Hutchinson Center researchers first to induce state of suspended animation in model vertebrate organism
4. Digging for genetic fossils: Hutchinson Center researchers solve structure of ancient biological molecule
5. Fred Hutchinson Cancer Research Center to lead international team to accelerate investigation of immune-related genes
6. Hutchinson Center researcher awarded Block lectureship
7. White House honors Hutchinson Center Scientist with Presidential Early Career Award
8. Hutchinson Center to lead $11.5 million ovarian-cancer research consortium
9. Fred Hutchinson Cancer Research Center researcher one of five awarded $1 million distinguished young scholars grant
10. Fred Hutchinson Cancer Research Center And Targeted Genetics Announces Issuance Of Braod Patent Covering Antigen-Specific T Cell Expansion
11. Hutchinson Center Director Wins Americas Nobel

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/13/2019)... (PRWEB) , ... June 13, 2019 , ... KICVentures ... of Spine & The Spine, Orthopedic and Pain Management-Driven ASC Conference in Chicago on ... & Resorts 323 E. Wacker Dr. Chicago, IL in the 3rd floor Ticino Hospitality ...
(Date:6/11/2019)... ... June 12, 2019 , ... ... services, Abveris plans to leverage the Geneious Biologics platform as a premium hub ... Technology Officer at Abveris, says: “The Geneious team has done an excellent job ...
(Date:6/6/2019)... (PRWEB) , ... June 05, 2019 , ... ... top companies and solutions in the global health and medical technology market, announced ... its “Best Healthcare Navigation / Robotics Solution” award in the 2019 MedTech Breakthrough ...
Breaking Biology News(10 mins):
(Date:5/31/2019)... TORONTO (PRWEB) , ... May 29, 2019 , ... For ... but the toughest forms of cancer demand breakthrough therapies. Advances in immuno-oncology have led ... a patient’s own T cells with engineered T cell receptors known as “CARs”. The ...
(Date:5/31/2019)... ... , ... World Compliance Seminars today announced a live seminar ... MA. This peer recommended interactive workshop is always selected by professionals at global ... with a compendial treatment of Data Integrity fundamentals. After laying the groundwork, the ...
(Date:5/31/2019)... ... 30, 2019 , ... A study released today in STEM ... the sustained release of human placental stem cell (HPSC)-derived conditioned medium (CM) to ... CM into the injured kidney, where it helped restore function and regenerate injured ...
(Date:5/21/2019)... ... May 21, 2019 , ... ... today officially opened the inaugural Africa Brewing Conference dedicated to sharing brewing knowledge, ... Africa. The event, which is supported through a partnership with “Ethiopia Invest”, will ...
Breaking Biology Technology:
Cached News: