HOME >> BIOLOGY >> NEWS
Freezing cancer cells makes them prime targets for anti-cancer drug, new study finds

Berkeley - The answer to improving the effectiveness of certain cancer treatments may be in stopping the malignant cells cold.

Two researchers from the Institut Gustave-Roussy in France and the University of California, Berkeley found that freezing cancer cells in test tubes made them far more vulnerable to attack by bleomycin, a potent anti-cancer drug also known by the brand name Blenoxane.

Cryosurgery - freezing cells to destroy them - and bleomycin are approved treatments currently used separately for cancer patients. But researchers of the study, published Tuesday, May 14, in the British Journal of Cancer, say that combining the two therapies may eventually lead to a powerful new form of cancer treatment that targets malignant cells while leaving healthy tissue unharmed.

"Cryosurgery has become increasingly popular over the past decade and is being used to treat tens of thousands of cancer patients all over the world," said Boris Rubinsky, professor of bioengineering and mechanical engineering at UC Berkeley and co-author of the study.

In the procedure, cryosurgeons insert a thin probe cooled with a cryogen - often argon gas or liquid nitrogen - into a tumor, turning the malignant mass into an ice ball. Doctors see precisely where they are operating in real time and can thus avoid freezing healthy tissue through the use of ultrasound imaging, a technique pioneered by Rubinsky and former UC San Francisco physician Gary Onik in 1981.

"The neat thing is this research really could have clinical applicability in a very rapid matter," said Onik, currently the director of surgical imaging at Florida Hospital Celebration Health's Center for Surgical Advancement in Orlando, and one of the reviewers of the study. "However, it is critical that we first conduct animal model studies so that we better understand the parameters and risks involved in using cryochemotherapy treatment in humans," he said.

Coverage for cryosurg
'"/>

Contact: Sarah Yang
scy@pa.urel.berkeley.edu
510-643-7741
University of California - Berkeley
14-May-2002


Page: 1 2 3 4

Related biology news :

1. Freezing human eggs - new findings point way to greater success
2. Scientists Trace Roots Of Protein That Keeps Antarctic Fish From Freezing
3. Leader in cancer treatment and prevention research honored
4. International study findings link acne-like rash to effectiveness of new targeted cancer treatment
5. Chemical derived from vitamin-E shows early promise as cancer drug
6. New molecular link key to cellular proteins involved in cancer progression, other diseases
7. Phase II trials of second-generation antisense cancer drug planned following successful early study
8. Trial shows which brain cancer patients benefit from temozolomide
9. Genetic differences might help distinguish thyroid cancers
10. Evidence builds for potential new cancer drug target
11. New sequence involved in DNA replication timing may aid in cancer detection

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/11/2019)... ... June 12, 2019 , ... ... discovery services, Abveris plans to leverage the Geneious Biologics platform as a premium ... Chief Technology Officer at Abveris, says: “The Geneious team has done an excellent ...
(Date:6/6/2019)... ... June 05, 2019 , ... Ziegler, ... financial advisor to Pathologists Bio-Medical Laboratories (PBM) on its recent acquisition by PathGroup. ... platform that provides services to more than one dozen hospitals and surgery centers ...
(Date:6/4/2019)... ... 04, 2019 , ... Most preclinical EEG visualization platforms offer ... usually based on variations of amplitude, frequency or spike train detection. In the ... to the complexity and variability of the signal, and automation tools are used ...
Breaking Biology News(10 mins):
(Date:5/7/2019)... British Columbia (PRWEB) , ... May 06, 2019 ... ... be a go-to resource for the growing number of repositories being asked to ... We are grateful to the team of contributors who are world leaders, who ...
(Date:5/2/2019)... ... , ... Stay on top of current hot topics through free webinars presented ... webinars is free, so be sure to register today to save your place! Participate ... to see our upcoming webinars: , CLINICAL TRIALS , May 7 – Oncology Clinical ...
(Date:4/18/2019)... ... 18, 2019 , ... Taking a step closer to a ... at Worcester Polytechnic Institute (WPI) has developed a novel process using an unusual ... and other biofuels more economically. , Isobutanol, like ethanol, is an alcohol, but ...
(Date:4/10/2019)... (PRWEB) , ... April 10, ... ... both regenerative medicine manufacturing technology leaders, have locked into multiple agreements to ... before. Companies across the regenerative medicine industry, ranging from synthetic biology companies ...
Breaking Biology Technology:
Cached News: