HOME >> BIOLOGY >> NEWS
Fruit fly's genome sequence finished in record time: Physical maps are the key to accuracy

BERKELEY, CA -- In 90 years of study, the diminutive fruit fly Drosophila melanogaster has yielded many of the most fundamental discoveries in genetics -- beginning with proof, in 1916, that the genes are located on the chromosomes. Only during the last year has the fly's whole genome been sequenced, however, and its 13,601 individual genes enumerated.

The genome of D. melanogaster, the largest yet sequenced in full, is described in the 24 March 2000 issue of Science magazine, in a series of articles jointly authored by hundreds of scientists, technicians, and students from 20 public and private institutions in five countries.

The collaboration was led by Gerald Rubin of the University of California at Berkeley and the Howard Hughes Medical Institute (HHMI), who heads the Berkeley Drosophila Genome Project, and by J. Craig Venter of Celera Genomics in Rockville, Maryland. The Berkeley Drosophila Genome Project (BDGP) is supported by the Department of Energy, the National Human Genome Research Institute, and HHMI, with the largest of its facilities operated by the Life Sciences Division of the Department of Energy's Lawrence Berkeley National Laboratory.

In 1998, when collaboration with Celera began, extensive but incomplete maps of the location of specific DNA sequences on the fly chromosomes had been constructed, and about 20 percent of the fly genome had already been sequenced in detail -- mostly by the BDGP group at Berkeley Lab where, with Rubin, Susan Celniker is co-director of the sequencing effort.

The purpose of the collaboration was to test whether a strategy known as whole-genome shotgun sequencing could be used on organisms having many thousands of genes encoded in millions of DNA base pairs; the strategy had proven effective for small bacterial genomes.

"No one knew whether whole-genome shotgun sequencing would work for the fly genome," says Roger Hoskins, leader of the BDGP physical mapping project, "but we knew that if it did, i
'"/>

Contact: Paul Preuss
paul_preuss@lbl.gov
510-486-6249
DOE/Lawrence Berkeley National Laboratory
23-Mar-2000


Page: 1 2 3 4

Related biology news :

1. Fruits offer powerful protection from skin cancer
2. Fruit odors lure some flies to evolve into new species
3. Fruit fly pheromone receptor first ever discovered linked to specific sexual behavior
4. Fruit consumption related to increased risk of Parkinsons?
5. Fruit fly cells reveal Hedgehogs secrets
6. Fruit flies unlock Methuselahs secrets
7. Fruit fly model could explain how mosquitoes carry malaria: new drugs and vaccines on the horizon
8. Research Bears Fruit, And Patents
9. Compounds From Fruits, Vegetables And Grains Slow The Growth Of Human Tumor Cells
10. Variations In The Human Homologue Of A Fruit Fly Gene Are Associated With Mood And Panic Disorders
11. Fruit-Fly Mating May Produce A Game Of Evolutionary Leapfrog

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/23/2017)... Research and Markets has announced the addition of the "Global ... 2025" report to their offering. ... The Global Vehicle Anti-Theft System Market is ... next decade to reach approximately $14.21 billion by 2025. ... all the given segments on global as well as regional levels ...
(Date:3/22/2017)... 21, 2017 Optimove , provider ... retailers such as 1-800-Flowers and AdoreMe, today announced ... and Replenishment. Using Optimove,s machine learning algorithms, these ... and replenishment recommendations to their customers based not ... of customer intent drawn from a complex web ...
(Date:3/20/2017)... 2017 At this year,s CeBIT Chancellor Dr. ... DERMALOG. The Chancellor came to the DERMALOG stand together with the Japanese ... CeBIT partner country. At the largest German biometrics company the two government ... and iris recognition as well as DERMALOG´s multi-biometrics system.   ... ...
Breaking Biology News(10 mins):
(Date:7/17/2017)... ... July 17, 2017 , ... DuPont Pioneer today announced ... website (openinnovation.pioneer.com) dedicated to connecting third-party innovators with DuPont Pioneer scientists is ... enabling technologies, biologicals and digital solutions. , “DuPont Pioneer is building on its ...
(Date:7/15/2017)... ... ... Cuvette manufacturer FireflySci has been making many products for the ... have learned that their biggest asset was their amazing customer base. Through listening ... to meet the changing needs of scientists at a rapid pace. , For decades, ...
(Date:7/14/2017)... ... July 13, 2017 , ... ... calibration verification test kit has received US FDA 510 (k) clearance for use ... plasma matrix, evaluates D-Dimer. Each VALIDATE® D-Dimer kit, prepared using the CLSI EP06-A ...
(Date:7/13/2017)... ... July 13, 2017 , ... ... in Specialty Pharmacy. URAC is the independent leader in promoting healthcare quality through ... comprehensive commitment to quality care, improved processes and better patient outcomes. , ...
Breaking Biology Technology:
Cached News: