HOME >> BIOLOGY >> NEWS
Fruit fly's genome sequence finished in record time: Physical maps are the key to accuracy

BERKELEY, CA -- In 90 years of study, the diminutive fruit fly Drosophila melanogaster has yielded many of the most fundamental discoveries in genetics -- beginning with proof, in 1916, that the genes are located on the chromosomes. Only during the last year has the fly's whole genome been sequenced, however, and its 13,601 individual genes enumerated.

The genome of D. melanogaster, the largest yet sequenced in full, is described in the 24 March 2000 issue of Science magazine, in a series of articles jointly authored by hundreds of scientists, technicians, and students from 20 public and private institutions in five countries.

The collaboration was led by Gerald Rubin of the University of California at Berkeley and the Howard Hughes Medical Institute (HHMI), who heads the Berkeley Drosophila Genome Project, and by J. Craig Venter of Celera Genomics in Rockville, Maryland. The Berkeley Drosophila Genome Project (BDGP) is supported by the Department of Energy, the National Human Genome Research Institute, and HHMI, with the largest of its facilities operated by the Life Sciences Division of the Department of Energy's Lawrence Berkeley National Laboratory.

In 1998, when collaboration with Celera began, extensive but incomplete maps of the location of specific DNA sequences on the fly chromosomes had been constructed, and about 20 percent of the fly genome had already been sequenced in detail -- mostly by the BDGP group at Berkeley Lab where, with Rubin, Susan Celniker is co-director of the sequencing effort.

The purpose of the collaboration was to test whether a strategy known as whole-genome shotgun sequencing could be used on organisms having many thousands of genes encoded in millions of DNA base pairs; the strategy had proven effective for small bacterial genomes.

"No one knew whether whole-genome shotgun sequencing would work for the fly genome," says Roger Hoskins, leader of the BDGP physical mapping project, "but we knew that if it did, i
'"/>

Contact: Paul Preuss
paul_preuss@lbl.gov
510-486-6249
DOE/Lawrence Berkeley National Laboratory
23-Mar-2000


Page: 1 2 3 4

Related biology news :

1. Fruits offer powerful protection from skin cancer
2. Fruit odors lure some flies to evolve into new species
3. Fruit fly pheromone receptor first ever discovered linked to specific sexual behavior
4. Fruit consumption related to increased risk of Parkinsons?
5. Fruit fly cells reveal Hedgehogs secrets
6. Fruit flies unlock Methuselahs secrets
7. Fruit fly model could explain how mosquitoes carry malaria: new drugs and vaccines on the horizon
8. Research Bears Fruit, And Patents
9. Compounds From Fruits, Vegetables And Grains Slow The Growth Of Human Tumor Cells
10. Variations In The Human Homologue Of A Fruit Fly Gene Are Associated With Mood And Panic Disorders
11. Fruit-Fly Mating May Produce A Game Of Evolutionary Leapfrog

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/3/2016)... 2016 Das DOTM ... Nepal hat ein 44 Millionen ... Kennzeichen, einschließlich Personalisierung, Registrierung und IT-Infrastruktur, an ... und Implementierung von Identitätsmanagementlösungen. Zahlreiche renommierte internationale ... teilgenommen, aber Decatur wurde als konformste und ...
(Date:5/24/2016)... -- Ampronix facilitates superior patient care by providing unparalleled technology to leaders of the ... latest premium product recently added to the range of products distributed by Ampronix. ... ... ... Display- Ampronix News ...
(Date:5/3/2016)... 2016  Neurotechnology, a provider of high-precision biometric ... Biometric Identification System (ABIS) , a complete system ... ABIS can process multiple complex biometric transactions with ... fingerprint, face or iris biometrics. It leverages the ... MegaMatcher Accelerator , which have been used ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... Prostate Cancer Foundation (PCF) is pleased to announce 24 new Young ... cancer. Members of the Class of 2016 were selected from a pool of ... More About the Class of 2016 PCF Young Investigators ... ... ...
(Date:6/23/2016)... ... ... STACS DNA Inc., the sample tracking software company, today announced that Dr. ... STACS DNA as a Field Application Specialist. , “I am thrilled that Dr. ... STACS DNA. “In further expanding our capacity as a scientific integrator, Hays brings a ...
(Date:6/23/2016)... , June 23, 2016 ... Hematology Review, 2016;12(1):22-8 http://doi.org/10.17925/OHR.2016.12.01.22 ... , the peer-reviewed journal from touchONCOLOGY, Andrew ... escalating cost of cancer care is placing an ... result of expensive biologic therapies. With the patents ...
(Date:6/23/2016)... ... June 23, 2016 , ... Velocity ... intelligent tools designed, tuned and optimized exclusively for Okuma CNC machining centers at ... result of a collaboration among several companies with expertise in toolholding, cutting tools, ...
Breaking Biology Technology:
Cached News: