HOME >> BIOLOGY >> NEWS
Fruit fly's genome sequence finished in record time: Physical maps are the key to accuracy

BERKELEY, CA -- In 90 years of study, the diminutive fruit fly Drosophila melanogaster has yielded many of the most fundamental discoveries in genetics -- beginning with proof, in 1916, that the genes are located on the chromosomes. Only during the last year has the fly's whole genome been sequenced, however, and its 13,601 individual genes enumerated.

The genome of D. melanogaster, the largest yet sequenced in full, is described in the 24 March 2000 issue of Science magazine, in a series of articles jointly authored by hundreds of scientists, technicians, and students from 20 public and private institutions in five countries.

The collaboration was led by Gerald Rubin of the University of California at Berkeley and the Howard Hughes Medical Institute (HHMI), who heads the Berkeley Drosophila Genome Project, and by J. Craig Venter of Celera Genomics in Rockville, Maryland. The Berkeley Drosophila Genome Project (BDGP) is supported by the Department of Energy, the National Human Genome Research Institute, and HHMI, with the largest of its facilities operated by the Life Sciences Division of the Department of Energy's Lawrence Berkeley National Laboratory.

In 1998, when collaboration with Celera began, extensive but incomplete maps of the location of specific DNA sequences on the fly chromosomes had been constructed, and about 20 percent of the fly genome had already been sequenced in detail -- mostly by the BDGP group at Berkeley Lab where, with Rubin, Susan Celniker is co-director of the sequencing effort.

The purpose of the collaboration was to test whether a strategy known as whole-genome shotgun sequencing could be used on organisms having many thousands of genes encoded in millions of DNA base pairs; the strategy had proven effective for small bacterial genomes.

"No one knew whether whole-genome shotgun sequencing would work for the fly genome," says Roger Hoskins, leader of the BDGP physical mapping project, "but we knew that if it did, i
'"/>

Contact: Paul Preuss
paul_preuss@lbl.gov
510-486-6249
DOE/Lawrence Berkeley National Laboratory
23-Mar-2000


Page: 1 2 3 4

Related biology news :

1. Fruits offer powerful protection from skin cancer
2. Fruit odors lure some flies to evolve into new species
3. Fruit fly pheromone receptor first ever discovered linked to specific sexual behavior
4. Fruit consumption related to increased risk of Parkinsons?
5. Fruit fly cells reveal Hedgehogs secrets
6. Fruit flies unlock Methuselahs secrets
7. Fruit fly model could explain how mosquitoes carry malaria: new drugs and vaccines on the horizon
8. Research Bears Fruit, And Patents
9. Compounds From Fruits, Vegetables And Grains Slow The Growth Of Human Tumor Cells
10. Variations In The Human Homologue Of A Fruit Fly Gene Are Associated With Mood And Panic Disorders
11. Fruit-Fly Mating May Produce A Game Of Evolutionary Leapfrog

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/14/2017)... , June 15, 2017  IBM (NYSE: IBM ) ... international tech event dedicated to developing collaboration between startups and ... on June 15-17. During the event, nine startups will showcase ... value in various industries. France ... the international market, with a 30 percent increase in the ...
(Date:5/16/2017)... TEANECK, N.J. , May 16, 2017  Veratad ... leading provider of online age and identity verification solutions, ... the K(NO)W Identity Conference 2017, May 15 thru May ... Ronald Regan Building and International Trade Center. ... across the globe and in today,s quickly evolving digital ...
(Date:5/6/2017)... RAM Group , Singaporean based ... in biometric authentication based on a novel  ... to perform biometric authentication. These new sensors are based on ... Ram Group and its partners. This sensor will have ... and security. Ram Group is a next generation ...
Breaking Biology News(10 mins):
(Date:9/14/2017)... ... September 14, 2017 , ... AIM Global, the worldwide standards ... Inc. has won the 2017 Case Study Competition for AIDC. The award is ... that decrease risk” and push the adoption of automated data collection systems further. ...
(Date:9/13/2017)... ... September 13, 2017 , ... AMRI, a global ... improve patient outcomes and quality of life for more than 25 years, today ... US expert to the International Standards Organization/Technical Committee 194: Biological and Clinical ...
(Date:9/12/2017)... ... 12, 2017 , ... PhysIQ, a Chicago-based company that provides ... monitoring and clinical trial support, earned DPharm Idol 2017 honors at the 7th ... Launched in 2005, PhysIQ leverages artificial intelligence (AI) to empower digital health. The ...
(Date:9/12/2017)... NC (PRWEB) , ... September ... ... Inc. ( http://www.globalspecimensolutions.com ) has announced the release of their latest product ... workflows and storage requirements. LabCODE™ offers pre-built capabilities for Biobanking, Pharmacokinetics, ...
Breaking Biology Technology:
Cached News: