Fundamental structural differences discovered in brains of autistic individuals

Autistic individuals have a fundamental structural difference in the alignment and wiring of their brain cells, a difference that explains these individuals' proclivity to live in their own world, according to researchers.

"The fundamental structure by which they think and process information is different," said Dr. Manuel F. Casanova, neurologist and neuropathologist at the Medical College of Georgia and lead author on research findings published in the Feb. 12 issue of Neurology. The structural difference they have found would result in too much communication, too little inhibition and a tendency to shut out much of the world around them, the researchers said.

Dr. Casanova's research team members examined the brain tissue of nine autistic people with a mean age of 12 and found to their surprise that not only do they have smaller minicolumns a basic organizational unit of 80 to100 brain cells and their connective wiring they have more of them. The team reproduced its findings using a different method of microscopic analysis before submitting them for publication.

"We believe that we have uncovered a major source of pathology that has been untouched before because no one looked at minicolumns," Dr. Casanova said. "I pray we are correct because this is standing on the verge of something that could be very important to many people."

The team previously published studies indicating that microscopic differences in the minicolumns of man and non-human primates help explain man's capacity for complex communication. They also postulated that differences in the minicolumns might hold clues to conditions such as autism and schizophrenia in which communication is dramatically impacted. "Intelligence is not the property of single cells, it's in the circuitry," Dr. Casanova said, referring to the minicolumns where cells take in information, process it and respond.

Despite the general observation that autistic individuals tend to have unusua

Contact: Toni Baker
Medical College of Georgia

Page: 1 2 3

Related biology news :

1. Fundamental change to Immunology 101
2. New amino acid discovered; Fundamental building block of life
3. Fighting Mycobacterium tuberculosis with structural proteomics
4. Researchers view proteins structural changes in real time
5. Corvas presents 3-D molecular structure of matriptase, first structural insight into new class of protease cancer targets
6. Translating the human genome into protein function: structural genomics research at Columbia
7. CWRU med school snares $3 million Howard Hughes Institute grant to build structural biology program
8. University of Chicago receives $2.4 million grant from Howard Hughes Medical Institute to support immunology and structural biology programs
9. Genetic differences might help distinguish thyroid cancers
10. Study explains spatial orientation differences between sexes
11. Carnegie Mellon U. imaging study reveals sex-based differences that persist as mice enter adulthood

Post Your Comments:

(Date:8/12/2020)... (PRWEB) , ... August 12, 2020 , ... ... and monitoring systems that are ideal for public health agencies of all sizes. ... contagious diseases and helping at-risk individuals find appropriate health care, Mosio helps public ...
(Date:8/5/2020)... ... ... Regenative Labs has received approval from the Centers for Medicare & Medicaid ... Wharton’s jelly allografts to be assigned a Q code and be approved for application ... jelly allograft product to be recognized as a 361 HCT/P by CMS regulated under ...
(Date:7/31/2020)... ... July 30, 2020 , ... Justin Zamirowski to lead upcoming ... term focus on Type 2 diabetes and associated comorbidities. , Justin brings over ... and classes. As Chief Commercial Officer, Justin will lead Better Therapeutics’ ...
Breaking Biology News(10 mins):
(Date:7/1/2020)... ... June 29, 2020 , ... ... growth of 40% in 2020, despite many obstacles created as a result of ... increase revenue for its partnered medical practices and medical manufacturers by expanding access ...
(Date:7/1/2020)... WESTMINSTER, Colo. (PRWEB) , ... ... ... providers of expert tissue data insights, today announced that the launch of ... PD-L1 results along with data about the tumor microenvironment (TME). , “Flagship’s ...
(Date:6/28/2020)... JOSE, Calif. (PRWEB) , ... June 25, 2020 ... ... globe, researchers are racing to develop a vaccine or drug treatment. In an ... Recursion has publicly released the world’s largest imaging dataset portraying therapeutic ...
(Date:6/28/2020)... Md. (PRWEB) , ... June 26, 2020 , ... ... trade association representing security solutions providers, today announced its strong opposition to the ... The bill would impose a blanket ban on most federal use of nearly ...
Breaking Biology Technology:
Cached News: