Gastric emptying for specific foods may be key to managing deadly illnesses in elderly

April 22, 2003 (Bethesda, MD) -- The rate of gastric emptying is a major measure of the glucose and cardiovascular responses to oral carbohydrates. The former is key to the dietary management of people with diabetes mellitus, in whom strict control of blood glucose has been shown to reduce microvascular complications. As cardiovascular responses are relevant to the prevention of postprandial hypotension (subnormal arterial blood pressure following a meal), this can be an important clinical problem. Both Type 2 diabetes and postprandial hypotension occur most frequently in the elderly.

Now, a team of Australian physiologists has produced evidence that the gastric emptying, or nutrient absorption, for specific foods, may hold the answer for dietary management of deadly illnesses affecting the elderly population.


An individuals blood glucose levels after eating are influenced by a number of factors but it is now recognized that gastric emptying accounts for at least 35 percent of the variance in peak postprandial glucose levels after oral glucose (75 grams) in both healthy individuals and patients with Type 2 diabetes. Controlling gastric emptying by dietary and pharmacological means in order to minimize postprandial glucose represents a new approach to glycemic control. Studies in rodents have established the importance of early insulin release in the control of postprandial glucose excursions in that a small, early increase in blood/portal insulin levels is more effective than a larger, later increase in reducing blood glucose levels.

Thus, whereas slowing of nutrient absorption may benefit Type 2 diabetes patients, it is possible that modest acceleration of the initial gastric emptying rate of carbohydrates would have a beneficial effect on overall glycemia in Type 2 diabetes. This would also be true among healthy subjects because it would to an increase in early insulin release, particularly if the subsequent empty

Contact: Donna Krupa
American Physiological Society

Page: 1 2 3 4 5

Related biology news :

1. H Pylori Screening To Reduce The Risk Of Gastric Cancer
2. Veterans with Gulf War syndrome have damage in specific, primitive portion of nervous system
3. Resveratrol synthase uncovered: Cyclization specificity of type III polyketide synthases
4. Anticancer drug zebularine specifically targets tumor cells
5. PCB breakdown in rivers depends on sediment-specific bacteria, find Carnegie Mellon U. scientists
6. X marks the spot: Vector insertion is viral specific
7. Triple-vaccine strategy stimulates strong HIV-specific immune response in monkeys
8. Sex-specific differences in gene expression related to drug metabolism and hypertension
9. New papillomavirus target could lead to specific antiviral drugs for precancerous cervical lesions
10. Lack of specific brain protein causes marked deficits in learning, memory
11. HIV exhausts the immune system through chronic non-specific activation

Post Your Comments:

(Date:8/26/2020)... ... August 25, 2020 , ... ... company developing novel pharmaceuticals targeting mitochondria, in partnership with Essex Bio-Technology, a ... its pivotal U.S. Phase 3 VISTA-2 study of SkQ1 ophthalmic solution in ...
(Date:8/21/2020)... , ... August 18, 2020 , ... ... cell therapy, today announced that the U.S. Food and Drug Administration (FDA) has ... lead asset, SBI-101, for the treatment of severe COVID-19. Approval of this IND ...
(Date:8/12/2020)... ... August 11, 2020 , ... Both ... NJ, have entered into license agreements with Housey Pharma’s HMI subsidiary to gain ... and J&J have annual Research and Development spending in excess of US $10 ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... ... July 29, 2020 , ... G-CON Manufacturing, the leader ... tagline, “BUILDING FOR LIFE.” The adoption of this taglines comes at a time ... track capacity to provide patients with urgently needed vaccines and other lifesaving pharmaceutical ...
(Date:7/31/2020)... ... 2020 , ... eSource has long been touted as the solution to high ... eSource, the reasons it did not take off as quickly as people initially expected, ... is moving towards capturing data electronically for clinical trials and then repurposing it for ...
(Date:7/18/2020)... , ... July 16, 2020 , ... After research model ... completion of a great surgery is only the beginning of a successful study, while ... community. , Join Brad Gien, Global Head of Surgery from Envigo in ...
(Date:7/10/2020)... ... July 08, 2020 , ... ... announces a significant expansion of laboratory operations through its COVID-19 testing service, ... testing programs. , Bode-CARES provides a turnkey solution that includes ...
Breaking Biology Technology:
Cached News: