HOME >> BIOLOGY >> NEWS
Gene may link alcohol drinking and stress, mouse study suggests in Science

A release is available in Japanese by clicking here.

Why does stress make some people reach for a drink, but not others? Variations in a key stress-response gene may be at least one reason, suggests a German study on mice. The scientists report their findings in the journal Science, published by the American Association for the Advancement of Science.

Rainer Spanagel of the University of Heidelberg and the Max Planck Institute of Psychiatry found that mice lacking the "CRH1" gene drank more alcohol than normal mice did after stressful experiences.

If humans with variations in this gene behave the same way, a fairly simple test may identify recovering alcoholics likely to relapse under stress, according to Spanagel.

"We think that, with our model, we have the neurobiological mechanism underlying a very specific phenotype of alcoholic patient," Spanagel said. "Patients with alterations in this gene may be particularly susceptible to stress, and may respond with drinking."

Psychologists might then be able to help these patients, Spanagel suggested, teaching them coping strategies for stressful situations.

"We've long known that stress is the biggest cause of relapse for many, but not all addicts, even those who've long been in recovery. This important study points both to the underlying mechanisms of this effect and potential targets for prevention and treatment efforts," said Alan Leshner, Chief Executive Officer of AAAS, and formerly Director of the National Institute on Drug Abuse.

Researchers generally agree that stress-induced alcohol drinking and the tendency to relapse seem to have a significant genetic component, but the connection is not well understood. Some studies have implicated a signaling network in the brain, called the CRH system, that regulates hormonal and behavioral responses to stress.
'"/>

Contact: Lisa Onaga
lonaga@aaas.org
202-326-7088
American Association for the Advancement of Science
2-May-2002


Page: 1 2 3

Related biology news :

1. A liking for sweets, combined with novelty seeking, may predict alcoholism
2. Genes can influence both alcohol consumption and dependence
3. Infant rats eagerly accept high concentrations of alcohol upon first exposure
4. Acamprosate: potential medication for treating alcoholism
5. Antioxidants during pregnancy may help prevent birth defects tied to alcohol
6. Drunken worms reveal a genetic basis of alcohol response
7. Gene linked to alcoholism
8. Moderate alcohol consumption increases plasma levels of a protective hormone
9. Researchers find no link between alcohol consumption during pregnancy and asthma during childhood
10. Nonalcoholic beverages may impart cardiovascular benefits without the negative effects of alcohol
11. Gene therapy reduces drinking in rats with genetic predisposition to alcoholism

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Gene may link alcohol drinking and stress mouse study suggests Science

(Date:4/16/2014)... Sometimes known as Kennedy,s disease, spinal and bulbar muscular atrophy ... progressive muscle weakness and atrophy. Researchers have long considered it ... the cells in the spinal cord and brainstem that control ... the April 16, 2014 online issue of Neuron , ...
(Date:4/16/2014)... store memories improves during childhood, associated with structural changes ... parietal cortices. New research from UC Davis is exploring ... Eventually, that could give insights into disorders that typically ... affect memory, such as schizophrenia and depression. , Located ...
(Date:4/15/2014)... Ohio (April 16, 2014)A new study from the Women,s ... D levels and menopause symptoms. The study was published ... The North American Menopause Society., The authors analyzed the ... a number of menopause symptoms, including hot flashes, night ...
Breaking Biology News(10 mins):Mutant protein in muscle linked to neuromuscular disorder 2How kids' brain structures grow as memory develops 2Low Vitamin D may not be a culprit in menopause symptoms 2
(Date:1/15/2014)... Two champions of science, technology, engineering, and ... annual competition for middle and high school students designed ... study. The competition presents students with real-world problems experienced ... Mathematics, and Sciences is a program administered by ...
(Date:1/15/2014)... Freeslate, Inc ., the leading provider of ... one of India’s top five pharmaceutical companies, has received ... for high throughput solid form screening. , Lupin, ... range of quality, affordable generic and branded formulations and ...
(Date:1/14/2014)... Carahsoft and CDS Federal Services have ... at 2pm EST (11am PST), “Natural Language Processing: Converting ... how technology can turn raw, heterogeneous data into actionable ... The online webinar will last approximately one hour. , ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 EquitiesIQ, a ... Inc. (OTCQB: ALQA). Alliqua is an emerging biomedical company ... the wound care market. , Free report download: ... with a seasoned management team and Board, which launched ...
Breaking Biology Technology:Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3
Cached News: