HOME >> BIOLOGY >> NEWS
Gene may link alcohol drinking and stress, mouse study suggests in Science

A release is available in Japanese by clicking here.

Why does stress make some people reach for a drink, but not others? Variations in a key stress-response gene may be at least one reason, suggests a German study on mice. The scientists report their findings in the journal Science, published by the American Association for the Advancement of Science.

Rainer Spanagel of the University of Heidelberg and the Max Planck Institute of Psychiatry found that mice lacking the "CRH1" gene drank more alcohol than normal mice did after stressful experiences.

If humans with variations in this gene behave the same way, a fairly simple test may identify recovering alcoholics likely to relapse under stress, according to Spanagel.

"We think that, with our model, we have the neurobiological mechanism underlying a very specific phenotype of alcoholic patient," Spanagel said. "Patients with alterations in this gene may be particularly susceptible to stress, and may respond with drinking."

Psychologists might then be able to help these patients, Spanagel suggested, teaching them coping strategies for stressful situations.

"We've long known that stress is the biggest cause of relapse for many, but not all addicts, even those who've long been in recovery. This important study points both to the underlying mechanisms of this effect and potential targets for prevention and treatment efforts," said Alan Leshner, Chief Executive Officer of AAAS, and formerly Director of the National Institute on Drug Abuse.

Researchers generally agree that stress-induced alcohol drinking and the tendency to relapse seem to have a significant genetic component, but the connection is not well understood. Some studies have implicated a signaling network in the brain, called the CRH system, that regulates hormonal and behavioral responses to stress.
'"/>

Contact: Lisa Onaga
lonaga@aaas.org
202-326-7088
American Association for the Advancement of Science
2-May-2002


Page: 1 2 3

Related biology news :

1. A liking for sweets, combined with novelty seeking, may predict alcoholism
2. Genes can influence both alcohol consumption and dependence
3. Infant rats eagerly accept high concentrations of alcohol upon first exposure
4. Acamprosate: potential medication for treating alcoholism
5. Antioxidants during pregnancy may help prevent birth defects tied to alcohol
6. Drunken worms reveal a genetic basis of alcohol response
7. Gene linked to alcoholism
8. Moderate alcohol consumption increases plasma levels of a protective hormone
9. Researchers find no link between alcohol consumption during pregnancy and asthma during childhood
10. Nonalcoholic beverages may impart cardiovascular benefits without the negative effects of alcohol
11. Gene therapy reduces drinking in rats with genetic predisposition to alcoholism

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/12/2016)... DALLAS , May 12, 2016 ... has just published the overview results from the Q1 ... of the recent wave was consumers, receptivity to a ... wearables data with a health insurance company. ... choose to share," says Michael LaColla , CEO ...
(Date:4/28/2016)... and BANGALORE, India , April ... EdgeVerve Systems, a product subsidiary of Infosys (NYSE: ... today announced a global partnership that will provide ... to use mobile banking and payment services.      ... a key innovation area for financial services, but it also ...
(Date:4/26/2016)... April 27, 2016 Research ... Multi-modal Biometrics Market 2016-2020"  report to their offering.  ... The analysts forecast the global multimodal ... 15.49% during the period 2016-2020.  Multimodal ... sectors such as the healthcare, BFSI, transportation, automotive, ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... - BIOREM Inc. (TSX-V: BRM) ("Biorem" or "the Company") announces ... Clean Technology Fund I, LP and Clean Technology Fund ... venture capital funds which together hold approximately 59% of ... as converted basis), that they have entered into an ... in Biorem to TUS Holdings Co. Ltd. ("TUS") (en.tusholdings.com) ...
(Date:6/27/2016)... , ... June 27, 2016 , ... ... bring innovative medical technologies, services and solutions to the healthcare market. The company's ... of various distribution, manufacturing, sales and marketing strategies that are necessary to help ...
(Date:6/24/2016)... 2016  Regular discussions on a range of subjects including ... two entities said Poloz. Speaking at a lecture ... , he pointed to the country,s inflation target, which is ... "In certain areas there ... common economic goals, why not sit down and address strategy ...
(Date:6/23/2016)... WA (PRWEB) , ... June 23, 2016 , ... ... announces the release of its second eBook, “Clinical Trials Patient Recruitment and Retention ... recruitment and retention in this eBook by providing practical tips, tools, and strategies ...
Breaking Biology Technology:
Cached News: