Gene therapy may be a cure for post-radical prostatectomy erectile dysfunction

prophylactic treatment for men undergoing radical prostatectomy.

Radical prostatectomy is used to treat the early stages of prostate cancer by surgically removing the prostate gland and surrounding tissue. The procedure has a success rate of 70 to 85 percent. A high percentage of patients experience ED after the procedure due to injury to the peripheral nerves, including the cavernous nerve, located close to the prostate gland.

In addition to studying the use of gene therapy to treat post-radical prostatectomy ED, the team from the University of Pittsburgh also is investigating the potential of using muscle derived stem cells to regenerate the peripheral nerves often damaged by radical prostatectomy.

This study is published in abstract 1256 of the AUA proceedings.



Contact: Jocelyn Uhl
University of Pittsburgh Medical Center

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