Gene vital to radiation resistance in bacteria

NEW ORLEANS January 31, 2003 -- Researchers from Louisiana State University have identified a gene in the radiation-resistant bacterium Deinococcus radiodurans that they believe is vital to the organism's ability to withstand high levels of radiation. They report their findings today at the 3rd ASM/TIGR Conference on Microbial Genomes.

"When this gene (irrE) is not functional you have a very sensitive organism," says Ashlee Earl, a lead researcher on the study. "At a dose of radiation that would not normally kill D. radiodurans, there is less than .001 percent survival without irrE."

With a name that literally means "strange berry that can withstand radiation," D. radiodurans is the world's most radiation resistant organism, able to survive up to 1.5 million rads, over 1000 times more radiation than practically any other organism. For reference, 1000 rads is enough to kill the average human.

For decades scientists have been trying to figure out what makes it so hard to kill. Understanding how this bacterium survives such extreme conditions could help researchers with everything from cleaning up nuclear waste sites to preventing cancer.

To better define the mechanisms used by the bacterium to resist radiation, Earl and her team, which included researchers from The Institute for Genomic Research (TIGR), studied a mutant strain of D. radiodurans that could not survive high radiation levels. This strain carried mutations on two genes, one of which was irrE. When the irrE gene was restored, the bacterium was once again resistant to radiation, a finding that suggested the gene was responsible, at least in some part, for resistance.

Further study of irrE suggested that the gene is not directly responsible for DNA repair following radiation exposure but instead it controls other genes that are known in other organisms to be associated with DNA repair. It's role is also not specific to radiation. The gene is responsible in some part for D.

Contact: Jim Sliwa
American Society for Microbiology

Page: 1 2

Related biology news :

1. Medication reconciliation, pharmacist involvement vital to reducing medication errors, study finds
2. Education, monitoring vital for sport-fish eaters
3. Life goes on without vital DNA
4. Rb2 expression could play vital role in ovarian cancer Temple University researchers find
5. Vascular access vital to pump up tissue engineering
6. Study links amyloid plaques in Alzheimers brains to genes vital to normal memory
7. Family communication about hereditary disease vital to prevention
8. St. Jude researchers show that the Six3 gene is vital in the creation of the brains complexity
9. Wheat may be vital in battle against cancer and other diseases
10. Researchers describe atomic-size sorter that performs vital cellular function
11. Stem cell research is vital to finding cures for blinding diseases

Post Your Comments:
TAG: Gene vital radiation resistance bacteria

(Date:10/2/2015)... DUBLIN , Oct. 02 2015 ... addition of the "Enforcing the Law Using ... http://www.researchandmarkets.com/research/6kp5mx/enforcing_the_law ) has announced the addition of ... report to their offering. --> Research ... addition of the "Enforcing the Law Using ...
(Date:9/30/2015)... global glucose monitoring device and diabetes management market is valued ... on the industry from Kalorama Information. Sales in the traditional glucose ... continuous glucose monitoring and sensor segment, according to the healthcare ... in its latest report, The Global Glucose Monitoring Market ... , ...
(Date:9/28/2015)...  The monitoring of vital signs, such as ... an essential component of patient assessment. Changes in ... a patient,s condition. However, in general care areas ... during routine observation rounds only once every four ... these observation rounds, the warning signs can go ...
Breaking Biology News(10 mins):
(Date:10/9/2015)... HERSHEY, Pa. and ROCKVILLE, ... Therapeutics, Inc. ("ITI"), a privately-held biotechnology company developing ... today announced that it has entered into an ... on LAMP-vax products for the treatment or prevention ... Upon execution of the agreement, Immunomic Therapeutics will ...
(Date:10/9/2015)... ... October 09, 2015 , ... Leading microbial genomics startup uBiome ... better understand the relationship between weight management and the microbiome. The study uses the ... participants using an iPhone app. , The uBiome app is available as a free ...
(Date:10/8/2015)... N.J. , Oct. 8, 2015  Genetic testing ... may aid the identification of more couples at risk ... a study presented today at the 2015 American Society ... October 10 in Baltimore, Maryland . ... Quest Diagnostics (NYSE: DGX ) are presenting at ...
(Date:10/8/2015)... , October 8, 2015 ... .   --> Goldman Small Cap ... the small cap and microcap sectors, announced today ... report on PharmaCyte Biotech, Inc. (OTCQB - PMCB), ... on developing and preparing treatments for cancer and ...
Breaking Biology Technology:
Cached News: