HOME >> BIOLOGY >> NEWS
Gene vital to radiation resistance in bacteria

NEW ORLEANS January 31, 2003 -- Researchers from Louisiana State University have identified a gene in the radiation-resistant bacterium Deinococcus radiodurans that they believe is vital to the organism's ability to withstand high levels of radiation. They report their findings today at the 3rd ASM/TIGR Conference on Microbial Genomes.

"When this gene (irrE) is not functional you have a very sensitive organism," says Ashlee Earl, a lead researcher on the study. "At a dose of radiation that would not normally kill D. radiodurans, there is less than .001 percent survival without irrE."

With a name that literally means "strange berry that can withstand radiation," D. radiodurans is the world's most radiation resistant organism, able to survive up to 1.5 million rads, over 1000 times more radiation than practically any other organism. For reference, 1000 rads is enough to kill the average human.

For decades scientists have been trying to figure out what makes it so hard to kill. Understanding how this bacterium survives such extreme conditions could help researchers with everything from cleaning up nuclear waste sites to preventing cancer.

To better define the mechanisms used by the bacterium to resist radiation, Earl and her team, which included researchers from The Institute for Genomic Research (TIGR), studied a mutant strain of D. radiodurans that could not survive high radiation levels. This strain carried mutations on two genes, one of which was irrE. When the irrE gene was restored, the bacterium was once again resistant to radiation, a finding that suggested the gene was responsible, at least in some part, for resistance.

Further study of irrE suggested that the gene is not directly responsible for DNA repair following radiation exposure but instead it controls other genes that are known in other organisms to be associated with DNA repair. It's role is also not specific to radiation. The gene is responsible in some part for D.
'"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
31-Jan-2003


Page: 1 2

Related biology news :

1. Medication reconciliation, pharmacist involvement vital to reducing medication errors, study finds
2. Education, monitoring vital for sport-fish eaters
3. Life goes on without vital DNA
4. Rb2 expression could play vital role in ovarian cancer Temple University researchers find
5. Vascular access vital to pump up tissue engineering
6. Study links amyloid plaques in Alzheimers brains to genes vital to normal memory
7. Family communication about hereditary disease vital to prevention
8. St. Jude researchers show that the Six3 gene is vital in the creation of the brains complexity
9. Wheat may be vital in battle against cancer and other diseases
10. Researchers describe atomic-size sorter that performs vital cellular function
11. Stem cell research is vital to finding cures for blinding diseases

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/22/2016)... , June 22, 2016 On Monday, the ... to industry to share solutions for the Biometric Exit ... Customs and Border Protection (CBP), explains that CBP intends ... departing the United States , in ... to defeat imposters. Logo - http://photos.prnewswire.com/prnh/20160622/382209LOGO ...
(Date:6/9/2016)... , June 9, 2016  Perkotek an innovation leader in attendance control systems ... seamlessly log work hours, for employers to make sure the right employees are actually ... http://photos.prnewswire.com/prnh/20160609/377486LOGO ... ... ...
(Date:6/2/2016)... --  The Weather Company , an IBM Business (NYSE: ... in which consumers will be able to interact with IBM ... voice or text and receive relevant information about the product ... have long sought an advertising solution that can create a ... and valuable; and can scale across millions of interactions and ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... June 23, 2016 , ... Regulatory Compliance Associates® Inc. (RCA), ... free webinar on Performing Quality Investigations: Getting to Root Cause. ... no charge. , Incomplete investigations are still a major concern to the Regulatory ...
(Date:6/23/2016)... FRANCISCO , June 22, 2016  Amgen (NASDAQ: ... sponsorship of the QB3@953 life sciences incubator ... human health. The shared laboratory space at QB3@953 was ... overcome a key obstacle for many early stage organizations ... part of the sponsorship, Amgen launched two "Amgen Golden ...
(Date:6/22/2016)... June 22, 2016 Cell Applications, Inc. ... them to produce up to one billion human ... within one week. These high-quality, consistent stem cells ... cells and spend more time doing meaningful, relevant ... proprietary, high-volume manufacturing process that produces affordable, reliable ...
(Date:6/22/2016)...  According to Kalorama Information, the dominant trends ... include significant efforts in automation as well as ... affordable sequencers, say the healthcare market research firm, ... sample prep materials.  The healthcare market research company,s ... Next Generation Sequencing (NGS) , highlights major trends ...
Breaking Biology Technology:
Cached News: