HOME >> BIOLOGY >> NEWS
Genome of first fungal pathogen unveiled

DURHAM, N.C. -- Geneticists at the Duke Institute for Genome Sciences and Policy (IGSP) and the University of Basel have unveiled the complete genome sequence of the pathogenic plant fungus Ashbya gossypii, which infects agricultural crops including cotton and citrus fruits in the tropics. The fungus has the smallest genome yet characterized among free-living eukaryotes. Eukaryotes are the single-celled and multicellular organisms that include fungi, plants and animals.

The team -- led by Fred Dietrich, Ph.D., of the IGSP's Center for Genome Technology, and Peter Phillipsen, Ph.D., of the University of Basel -- reported its findings online in the March 4, 2004, Science Express, the online version of the journal Science. The work was completed with the funding and collaboration of Novartis (now Syngenta) in Research Triangle Park, N.C. The researchers have no financial ties to Novartis or Syngenta.

The sequencing of the fungal genome has already shed light on the evolution of Saccharomyces cerevisiae -- the single-celled baker's yeast that scientists rely on for the study of many basic questions in cell biology. Furthermore, understanding the infectious microbe's genetic instructions might allow scientists to tease out the fundamental features responsible for some fungi's ability to cause disease, the researchers said.

"We expect many similarities in function among all types of fungal pathogens -- whether they infect plants or humans," said Dietrich, first author of the study. "Understanding one will provide insight into fungal pathogens in general in terms of the forces that drive them."

Ashbya's stripped-down genome -- containing just 9.2 million DNA base pairs, the fundamental building blocks of inheritance -- will further simplify the task of deciphering genes and their functions, he added. The genomes of other important fungal pathogens can include as many as 200 million base pairs, more than 2
'"/>

Contact: Kendall Morgan
kendall.morgan@duke.edu
919-684-4148
Duke University Medical Center
4-Mar-2004


Page: 1 2

Related biology news :

1. Wiley publishes Welcome to the Genome: A Users Guide to the Genetic Past, Present, and Future
2. Genome-wide screen reveals new tricks of old genes
3. Experimental Biology 2004 - Translating the Genome
4. European Virtual Institute for Genome Annotation receives 12 million Euro
5. Tools from the Human Genome Project reveal a versatile microbe
6. Francis Collins and Ari Patrinos receive Energy Secretarys Gold Award for Human Genome Project
7. Genomes of tiny microbes yield clues to global climate change
8. Genome researcher analyze chromosome 7
9. Genome sequence of bread mold revealed by international team, including Hebew University researcher
10. Genome analysis sheds light on drug-resistant pathogen
11. Genome of a major member of gut bacteria sequenced

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/5/2018)... ... October 04, 2018 , ... High dose of biotin may cause ... such as cardiac troponin has serious clinical complications. There is an increasing trend of ... still unknown. , High dose of biotin supplement use may continue to increase ...
(Date:10/3/2018)... ... October 03, 2018 , ... ... commercialization of first-in-class stromal cell immunotherapies, announced that ORBCEL-M™, a second generation ... diabetes and progressive diabetic kidney disease in a four-site, pan-European Phase I/II ...
(Date:10/2/2018)... ... October 02, 2018 , ... Through this webinar, sponsored by ... They will also learn the role of calcium kinetics in cardiac safety testing. The ... officer at PPSC Biography; and Tsang Wai Lam, an assay development scientist at PPSC. ...
Breaking Biology News(10 mins):
(Date:10/11/2018)... ... October 11, 2018 , ... ... and software solutions, in collaboration with HP, the global leader in printing, has ... GHS Chemical Labels on all HP PageWide Printers. , The award-winning Avery UltraDuty ...
(Date:10/5/2018)... ... 2018 , ... Earthres Group, Inc., a multi-disciplinary engineering firm, ... identity and better reflects its current breadth of markets and services. Marketing now ... related support services to clients in seven market sectors, and currently operates in ...
(Date:10/2/2018)... (PRWEB) , ... October 02, 2018 , ... ... or ignored, contamination endangers the reliability and reproducibility of experimental data. Each lab ... , In this educational webinar, which is sponsored by Eppendorf , attendees ...
(Date:9/28/2018)... ... September 28, 2018 , ... ... tech innovators, engineers, and scientists from around the world, is excited to announce ... of San Marcos, as the winner of the LabRoots Summer 2018 Textbook Scholarship, ...
Breaking Biology Technology:
Cached News: