HOME >> BIOLOGY >> NEWS
Genome researcher analyze chromosome 7

BETHESDA, Md., July 10, 2003 A detailed analysis of the reference sequence of chromosome 7 has uncovered structural features that appear to promote genetic changes that can cause disease, researchers from the International Human Genome Sequencing Consortium said today.

In a study published in the July 10 issue of the journal Nature, a multi-institution team, led by the Washington University School of Medicine in St. Louis, reported it had sequenced 99.4 percent of the gene-containing region of chromosome 7 to an accuracy of greater than 99.99 percent. The team also described its analysis of this highly accurate reference sequence, an effort that took advantage of recently released data on the mouse genome to refine gene predictions and zero in on chromosomal regions that may be of special interest in understanding genetic diseases.

In addition to representing the largest chromosome to date to undergo detailed sequence analysis, chromosome 7 is significant because it has served as a pioneering chromosome for genomic and genetic studies. Researchers first developed genome mapping techniques on chromosome 7, and in the late 1980s, this chromosome was also the first to be searched by a then-novel technique called positional cloning in the successful hunt for the cystic fibrosis gene.

"Chromosome 7 has long been of interest to the medical community. Besides containing many genes that are crucial to development, this chromosome also holds the gene for cystic fibrosis and is frequently damaged in some types of leukemia and other cancers," said Francis S. Collins, M.D., Ph.D., director of the National Human Genome Research Institute (NHGRI), which funded, and also participated in, the study. "This new analysis, coupled with our commitment to free and unrestricted access to sequence data, should further speed the discovery of genes on chromosome 7 related to human health and disease."

Among the study's most interesting results was the findi
'"/>

Contact: Geoff Spencer
spencerg@mail.nih.gov
301-402-0911
NIH/National Human Genome Research Institute
9-Jul-2003


Page: 1 2 3 4

Related biology news :

1. Wiley publishes Welcome to the Genome: A Users Guide to the Genetic Past, Present, and Future
2. Genome-wide screen reveals new tricks of old genes
3. Genome of first fungal pathogen unveiled
4. Experimental Biology 2004 - Translating the Genome
5. European Virtual Institute for Genome Annotation receives 12 million Euro
6. Tools from the Human Genome Project reveal a versatile microbe
7. Francis Collins and Ari Patrinos receive Energy Secretarys Gold Award for Human Genome Project
8. Genomes of tiny microbes yield clues to global climate change
9. Genome sequence of bread mold revealed by international team, including Hebew University researcher
10. Genome analysis sheds light on drug-resistant pathogen
11. Genome of a major member of gut bacteria sequenced

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/6/2018)... ... December 06, 2018 , ... Stewart has been on ... services, throughout his career. During his recent five-year tenure with InSphero he was ... the commercial laboratory operations in Brunswick, Maine. Through these experiences, Stewart has a ...
(Date:12/5/2018)... ... December 04, 2018 , ... Slone ... announces the placement of Michael Mercer at Karius, Inc. as Chief Commercial Officer. ... will be based at Karius' headquarters in Redwood City, California and report to ...
(Date:11/29/2018)... Calif. (PRWEB) , ... November 29, 2018 , ... ... Technologies, is excited to collaborate with the new NSF Engineering Research Center for ... and clinical collaborators brought together to develop transformative tools and technologies for the ...
Breaking Biology News(10 mins):
(Date:11/29/2018)... LEHI, Utah (PRWEB) , ... November 29, 2018 , ... ... round was led by Kickstart Seed Fund, with participation from existing investor and board ... Investors and Davis Smith of Cotopaxi. The additional funding will enable the company to ...
(Date:11/20/2018)... Columbia (PRWEB) , ... November 19, 2018 , ... ... is pleased to announce the release of the Chinese translation of Best Practices: ... January 2018, is a practice-changing publication aimed at advancing the science of biobanking ...
(Date:11/15/2018)... ... 2018 , ... Hüpnos announces the launch of ... It is estimated that 90 million Americans suffer from persistent snoring, ... resulting daytime fatigue causes extreme difficulty with concentration, focus and memory. It’s ...
(Date:11/13/2018)... ... November 13, 2018 , ... Aditya Humad, Managing Partner of ... that asserts it is still trending upward with growing valuations based on a ... market consolidation, pricing pressure and increased competition as reasons often cited by institutional ...
Breaking Biology Technology:
Cached News: