HOME >> BIOLOGY >> NEWS
Genome researcher analyze chromosome 7

his colleagues identified approximately 1,150 protein-coding genes on chromosome 7, about 20 percent less than the 1,455 predicted in a previous study by a different team.

The accuracy and completeness of the human chromosome 7 sequence assembled by the International Human Genome Sequencing Consortium was evaluated in part by Eric D. Green, M.D., Ph.D., and his colleagues at NHGRI's Genome Technology Branch. When they compared the representation of markers called sequence-tagged sites (STSs) in the recently assembled sequence with STSs in previously constructed physical and genetic maps of chromosome 7, the NHGRI researchers found an excellent overall concordance.

Dr. Green, who is NHGRI's scientific director and a co-author of the study, also emphasized the value of comparing the sequence of human chromosome 7 to its recently sequenced counterpart in the mouse. "Comparing the human sequence to the mouse sequence allowed our team to perform much more rigorous analyses of genes than would have otherwise been possible. The ability to place the human sequence alongside the mouse sequence helped us to swiftly distinguish real, protein-coding genes from pseudo-genes. The power of comparative genomics really sharpened our focus," Dr. Green said.

In addition to NHGRI and Washington University, other institutions taking part in the chromosome 7 analysis were: University of Washington Genome Center, Seattle; University of California, Santa Cruz; Case Western Reserve University School of Medicine, Cleveland; and EMBL, Heidelberg, Germany.

There are 23 pairs of chromosomes in the human genome, which bear the 3 billion DNA letters that carry the genetic blueprint for human life. Chromosome 7 is one of the larger chromosomes, containing about 5 percent of the DNA in the human genome.

The sequencing work on chromosome 7 was carried out at the Genome Sequencing Center at the Washington University School of Medicine as part of the Human Ge
'"/>

Contact: Geoff Spencer
spencerg@mail.nih.gov
301-402-0911
NIH/National Human Genome Research Institute
9-Jul-2003


Page: 1 2 3 4

Related biology news :

1. Wiley publishes Welcome to the Genome: A Users Guide to the Genetic Past, Present, and Future
2. Genome-wide screen reveals new tricks of old genes
3. Genome of first fungal pathogen unveiled
4. Experimental Biology 2004 - Translating the Genome
5. European Virtual Institute for Genome Annotation receives 12 million Euro
6. Tools from the Human Genome Project reveal a versatile microbe
7. Francis Collins and Ari Patrinos receive Energy Secretarys Gold Award for Human Genome Project
8. Genomes of tiny microbes yield clues to global climate change
9. Genome sequence of bread mold revealed by international team, including Hebew University researcher
10. Genome analysis sheds light on drug-resistant pathogen
11. Genome of a major member of gut bacteria sequenced

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/22/2020)... ... January 21, 2020 , ... ... operations, developing transport validation strategies, supporting global regulatory applications, and executing global ... the Houston Business Journal as a fastest growing company, and ISO 9001:2015 ...
(Date:1/8/2020)... SCOTTSDALE, Ariz. (PRWEB) , ... January 08, 2020 ... ... cellular therapies, is now offering complimentary overnight shipping to its nationwide practice ... of biologics, but also due to volume in its Network the biologics themselves ...
(Date:1/7/2020)... ... January 06, 2020 , ... Myant Inc. , the pioneers ... Vegas) to bring to life its vision of a world where textile-based interfaces knitted ... the AI-powered digital sphere, and the physical IoT-enabled environment. The experience at Myant’s booth ...
Breaking Biology News(10 mins):
(Date:1/8/2020)... ... January 08, 2020 , ... ... composites that can achieve specific properties for use in harsh environments inside or ... combines up to three metals or alloys to achieve specific properties such ...
(Date:1/7/2020)... ... January 06, 2020 , ... EconoFact, a non-profit ... Fletcher School at Tufts University, is pleased to announce that it was awarded ... administered by Tufts University, and will help to expand the scope, exposure and ...
(Date:12/31/2019)... N.J. (PRWEB) , ... December 31, 2019 , ... At ... the conference that will be broadly focused on 3D cell culture , ... its NASH 3D cell culture assays for assessing steatosis , inflammation and ...
(Date:12/23/2019)... ... December 23, 2019 , ... Leak Detection Associates, the leading ... Medical Device Industries, is excited to announce that it will be a contributing ... Closure Integrity Testing Basic Training Course . Held in conjunction with PDA Europe’s ...
Breaking Biology Technology:
Cached News: