HOME >> BIOLOGY >> NEWS
Genuine stem cells found in skin might treat hair loss, wounds

Master cells nestled within hair follicles of the skin retain the ability to form new hairs as well as skin, new research reported in the September 3 issue of Cell confirms. While earlier work had suggested the presence of stem cells in skin, the new study by Howard Hughes Medical Institute investigators at Rockefeller University in New York provides the first direct evidence that cells extracted from the hair follicles of mice exhibit all of the defining features of true stem cells. The skin stem cells offer potential new methods to reverse baldness and boost wound healing in burn victims and those suffering from other skin injuries, the researchers said.

The putative skin stem cells reproduce themselves seemingly indefinitely in the laboratory, the study found. When engrafted onto the backs of hairless mice, the cells also formed stretches of skin, tufts of hair, and sebaceous glands, which secrete an oily substance known as sebum that lubricates skin and hair.

"We've identified cells within skin that bear all the characteristics of true stem cells--the ability for self renewal and the multipotency required to differentiate into all lineages of epidermis and hair," said Elaine Fuchs, cell biologist at Rockefeller University and senior author of the study. "The results demonstrate for the first time that individual cells isolated from hair follicles can be cultured in the laboratory and retain a capacity to make multiple cell types when grafted."

The team's analysis of the versatile skin cells also offers new insights into the underlying genetic signature common to all stem cells, said the researchers.

Stem cells are undifferentiated cells whose daughters give rise to the specialized cell types that make up an organism. Embryonic stem cells, which emerge in the first days of an embryo's development, have the potential to differentiate, or specialize, into each of the 200 types of tissue in the body. In contrast, adult stem cells fou
'"/>

Contact: Heidi Hardman
hhardman@cell.com
617-397-2879
Cell Press
2-Sep-2004


Page: 1 2 3

Related biology news :

1. Preclinical safety study shows adipose-derived stem cells improve heart function after heart attack
2. Researchers develop fast track way to discover how cells are regulated
3. Chemical signals health of brain cells Symposium
4. New dye directly reveals activated proteins in living cells
5. NJIT professor receives Presidential Award for breakthrough research with adult stem cells
6. Complex cells likely arose from combination of bacterial and extreme-microbe genomes
7. Smac-ing back at cancer cells
8. Bone marrow cells routinely help with wound healing
9. Skin stem cells give hairless mice hair
10. Small, Smac-like molecule encourages death of cancer cells
11. Analysis of gene expression in lymphoid cells can determine lymphoma cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/21/2019)... ... December 20, 2019 , ... The City of Tampa ... SAGICO was on hand to honor these heroes. Tampa welcomed these most-highly decorated USA ... organizations and community leaders honored these distinguished service members. , The Medal of Honor, ...
(Date:12/18/2019)... ... December 17, 2019 , ... PM360, a ... and diagnostics industries, has named Pharmafusion LLC as one of the most innovative ... company and its founder/CEO Jonathan Retano. Earlier in the year, Pharmafusion was featured ...
(Date:12/14/2019)... , ... December 11, 2019 , ... ... solutions for the food and beverage industry won the 2019 Food Ingredient Europe’s ... to improve the rapidly growing plant-based foods category. Fiberstar who was one of ...
Breaking Biology News(10 mins):
(Date:11/27/2019)... , ... November 25, 2019 , ... ... has announced the company’s first robotic-assisted and navigated surgery in the UK. The ... (NHS) by acclaimed spine surgeons, Dr. Syed Aftab and Dr. Alexander Montgomery. The ...
(Date:11/20/2019)... ... November 20, 2019 , ... Defense and aerospace market intelligence ... generation units from 2019-2028. The value of this production is $728 million in ... worth $569 million. , Reference to 2017 is important, as that was ...
(Date:11/12/2019)... , ... November 12, 2019 ... ... enterprise software solutions for biopharmaceutical R&D, today announced that Immatics Biotechnologies ... adopted Genedata Biologics® to streamline their R&D operations related to ...
(Date:11/12/2019)... , ... November 12, 2019 , ... ... ever to educate Americans about the deadly healthcare-associated infection C. diff. The campaign, ... survivors of the epidemic, which kills at least 30,000 people in the U.S. ...
Breaking Biology Technology:
Cached News: