HOME >> BIOLOGY >> NEWS
Grant funds research to develop microbicide barrier to HIV

PITTSBURGH, Jan. 9 The National Institutes of Health (NIH) has awarded a grant of nearly $8 million to the University of Pittsburgh and Magee-Womens Research Institute (MWRI) to fund research aimed at developing a microbicide barrier to the human immunodeficiency virus (HIV), the virus that causes AIDS.

The grant, through the NIH's National Institute of Allergy and Infectious Diseases, marks the largest ever received thus far by project principal investigator Sharon Hillier, Ph.D., professor of obstetrics, gynecology and reproductive sciences and molecular genetics and biochemistry at the University of Pittsburgh School of Medicine.

"I believe fervently in trying to find a way to help women protect themselves against sexually transmitted infections, including HIV," said Dr. Hillier, who is also a senior investigator at MWRI. "Currently, women have no way to protect themselves except condoms, and women do not control condom use."

Dr. Hillier and her colleagues will pursue several scientific projects that involve UC781, a tight-binding molecule discovered by co-principal investigator Michael Parniak, Ph.D., professor of medicine in the division of infectious diseases at the University of Pittsburgh School of Medicine. An organic molecule about the size of an antibiotic, UC781 is a non-nucleoside reverse transcriptase inhibitor that renders the HIV virus incapable of infecting cells. These projects are:

  • Dr. Parniak will perform critical new studies evaluating the microbial activity of UC781, alone and in combination with other active components, against a variety of strains of HIV. This project is designed to focus on the extraordinary genetic diversity of HIV and the corresponding need to inactivate a wide spectrum of viral strains. These early tests will be done in vitro to determine both the efficacy of UC781 against HIV and its safety for use.

  • Phalguni Gupta, Ph.D., professor and assistant chairman of the division of
    '"/>


  • Contact: Michele Baum
    412-647-3555
    University of Pittsburgh Medical Center
    9-Jan-2003


    Page: 1 2 3

    Related biology news :

    1. Grant advances biochemical engineering laboratory
    2. GlaxoSmithKline Drug Discovery and Development Research Grant Program 2004
    3. Grant from GE Foundation to University of Houston to strengthen math, tech pipeline
    4. McGill Centre for Intellectual Property Policy receives $3 million SSHRC Grant
    5. Grant promotes marine ornamental fish aquaculture
    6. Grant of powerful computer to Rutgers-Newark will increase understanding of brain activity
    7. Grant renews funding of research toward cloning primates
    8. Lipids get the spotlight in new NIGMS Glue Grant
    9. Grant funds research to develop tissue-engineered solutions for heart disease
    10. Grant strengthens research arm of Penn State Hershey Medical Centers ALS Clinic
    11. Sea Grant News & Notes for March 26, 2003

    Post Your Comments:
    *Name:
    *Comment:
    *Email:


    (Date:11/2/2019)... ... ... Stay on top of current hot topics through free webinars presented by leading experts ... be sure to register today to save your place! Participate in the discussion and ... webinars: , CLINICAL OPERATIONS , November 14 – Leveraging Technology and Data to Establish ...
    (Date:10/30/2019)... ... October 30, 2019 , ... ... Credit Knowledge Center in which participants will learn about precision agriculture tools used ... to these technologies. , Participants will have the opportunity to visit Virginia ...
    (Date:10/30/2019)... ... 30, 2019 , ... Amberdata Inc., the leading blockchain and ... Capital, DF Capital, Rising Tide Fund, and HWVP. The new investment will ... its position as the leading data provider of institutional-grade blockchain and cryptoasset data. ...
    Breaking Biology News(10 mins):
    (Date:10/22/2019)... BOSTON (PRWEB) , ... October 22, 2019 , ... ... live biotherapeutics, has announced that its lead program, DBI-001, met its primary safety ... person open labeled phase 2a clinical trial for the treatment of interdigital tinea ...
    (Date:10/17/2019)... (PRWEB) , ... October 16, 2019 , ... ... provides personalized, easy-to-understand, web-based genetic counseling information, has published a new white paper ... year period and provides guidance as to how patients and medical providers can ...
    (Date:10/10/2019)... BETHESDA, Md. (PRWEB) , ... October 09, 2019 ... ... announced Amy Abernethy, MD, PhD, Principal Deputy Commissioner, FDA, as a newly-confirmed ... place 27–30 October 2019 in Las Vegas, Nevada USA. , Dr. Abernethy, a ...
    (Date:10/10/2019)... LAS VEGAS (PRWEB) , ... October 10, 2019 , ... ... training courses. The next course is October 18-19th, 2019 in Las Vegas with spots ... on exosomes. He completed training at several Ivy League universities including Cornell, Harvard and ...
    Breaking Biology Technology:
    Cached News: