Green Foundation, Trust gives $12.8 million for UT Southwestern comprehensive research center

ension of the Human Genome Project. For the first time we have all the pieces of the puzzle," he said. "The challenge is to put all the pieces together, and to do that will require sophisticated information technology as well as basic molecular biology and biochemistry."

Scientists now can use X-ray crystallography and magnetic resonance spectroscopy to solve the three-dimensional structures of important biological molecules especially proteins, Dr. Gilman noted. The newest computer-assisted imaging technologies also allow precise visualization of cell structures and analysis of cellular metabolism and function.

"A computer model of a cell or organ is a fantastic long-term goal, and it's absolutely going to happen someday. When we have such models, it will be spectacular. We'll be able to get new types of information on therapies, diseases and drug discovery. Drug discovery will become both faster and much less expensive," said Dr. Gilman. "But first, we need a model of the cell's signaling network. We can unite our efforts to make this happen under the umbrella of the new Green Center."

Dr. Gilman said he expects to recruit a core group of researchers who will collaborate with current UT Southwestern scientists to "form a nucleus of people who would work on the development of such models and collaborate with biologists to use their data to build such models."

Dr. Wildenthal said the new Green Comprehensive Center "not only will encourage interactions among UT Southwestern scientists, but also will facilitate collaborations with other institutions."

The Green Foundation's final distribution to UT Southwestern of approximately $11.3 million will be used to endow the new Green Comprehensive Center, which will be the home of three previously endowed chairs the Cecil H. and Ida Green Distinguished Chair in Reproductive Biology Sciences, the Cecil H. and Ida M. Green Chair in Biomedical Science, and the Cecil H. Green Distingui

Contact: Amanda Siegfried
UT Southwestern Medical Center

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