HOME >> BIOLOGY >> NEWS
Growing human organs on the farm

IT'S bad news, says your doctor. Your liver is failing. So he extracts stem cells from your bone marrow and injects them into a sheep fetus while it is still in the womb. When the sheep is born, much of the animal's liver will consist of your own cells-ready to be harvested and given back to you.

This dream therapy is still years off, if it happens at all, but the first steps have already been taken by a team led by Esmail Zanjani at the University of Nevada, Reno. "Esmail has some pretty startling results," says Alan Flake of the Children's Hospital of Philadelphia.

Zanjani's team hopes the animal-human chimeras they are creating (see "A question of breeding") will one day yield new cells genetically identical to a patient's own for repairing damaged organs, and perhaps larger pieces for transplantation.

It might even be possible to transfer whole organs, since in some cases having at least a partly human organ would be better than a purely animal xenotransplant. Immune rejection of the animal portion would still be a problem, but it is not insurmountable, says Flake. "I don't think that in 10 to 15 years that's out of the question."

If perfected, the technique could overcome some of the big stumbling blocks facing researchers who want to make tissues and organs for implants. It might yield significant quantities of just about any kind of cell or tissue, for instance, with no need to fiddle about with different culture conditions or growth factors.

Instead, the host animal's own developmental program guides the injected human stem cells into their final roles. "We take advantage of the growing nature of the fetus," Zanjani says. It would also allow doctors to obtain immune-compatible cells without having to create human embryos by therapeutic cloning. Human cells could be separated from the animal ones simply by modifying existing cell-sorting machines.

Providing the method really does produce normal human cel
'"/>

Contact: Claire Bowles
claire.bowles@rbi.co.uk
44-207-331-2751
New Scientist
17-Dec-2003


Page: 1 2 3 4

Related biology news :

1. Growing pains: T. Rex was teenage giant
2. Growing new breed of vaccine-producing plants to fight human diseases worldwide
3. Growing replacement teeth and dental tissues
4. Growing human antibodies in algae
5. Growing neurons use silencing mechanism to avoid disastrous tug-of-war
6. Growing Up On Their Own: Smart Plastics Organize Themselves Into Useful Optical Devices
7. Colorado State University Study Reveals Climate Change, Longer Growing Seasons Could Harm Grazing On Western Shortgrass Steppe
8. DNA Helps Track Origins Of Growing Blight Problem
9. Climate change plus human pressure caused large mammal extinctions in late Pleistocene
10. Lycopene slows human prostate tumour growth in mice and combined with vitamin E is even better
11. Most recent common ancestor of all living humans surprisingly recent

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/1/2020)... ... July 01, 2020 , ... Catalent, ... the purchase of Teva-Takeda Pharmaceuticals’ packaging facility in Minakuchi, located in the Shiga ... supply facility located in Kakegawa, the new 60,000-square-foot facility will provide customers with ...
(Date:6/28/2020)... ... June 25, 2020 , ... In an upcoming episode scheduled ... accelerated Point of Care Testing solutions (POCT). Check local listings for more info. , ... medical offices and are shipped to labs throughout the country. Results are then available ...
(Date:6/23/2020)... ... June 23, 2020 , ... First Aid Africa, ... a UK supplier and manufacturer of innovative portable renewable energy equipment, have announced ... fight against the COVID-19 pandemic in Zambia. , One of Renovagen’s FAST FOLD ...
Breaking Biology News(10 mins):
(Date:8/3/2020)... , ... August 03, 2020 , ... ... today announced Jim Corrigan, President and CEO has been named one of the ... cross-section of industry sectors, PharmaVoice 100 honorees are selected based on how they ...
(Date:7/31/2020)... ... 2020 , ... R3 Stem Cell International is now offering patients the opportunity ... cells total, patients may choose which extremities they would like treated. , Several studies ... Disord. 2016). At R3 International, umbilical cord tissue is obtained from a lab with ...
(Date:7/31/2020)... ... July 29, 2020 , ... ... transmitter systems that can be configured to drive Klystrons, TWTs, IOTs, and magnetrons. ... drive one or two switches in a push-pull configuration; yielding fast fall time ...
(Date:7/31/2020)... ... July 29, 2020 , ... Editas ... global provider of advanced delivery technologies, development, and manufacturing solutions for drugs, biologics, ... entered into a strategic partnership whereby Catalent will provide support for the development, ...
Breaking Biology Technology:
Cached News: