HOME >> BIOLOGY >> NEWS
Growth Factors Shown To Increase Vitamin C In The Immune System

New York, April 1, 1998 -- Ever since vitamin C was found to prevent scurvy -- a disease that has killed millions of people throughout history -- scientists have known that the vitamin plays an essential role in the body's defense against disease. Immune cells, for example, are known to accumulate and retain high levels of vitamin C, but just how this process occurs, has largely remained a mystery.

Now, researchers at Memorial Sloan-Kettering Cancer Center have found that the same class of proteins -- called growth factors -- which are known to control growth and production of immune cells also increase their ability to take up vitamin C. The findings, which are reported in the April issue of the journal Blood, shed new light on the connection between vitamin C and the immune system, showing how growth factors can increase the amount of vitamin C in immune cells.

"We now know that the growth factors that boost immunity also increase the amount of vitamin C in the immune cells," said Dr. David Golde, Physician-in-Chief of Memorial Sloan-Kettering Cancer Center and senior author of the study.

The researchers studied vitamin C in immune cells to determine whether growth factors played a role in regulating this process. Previous research had shown that growth factors caused immune cells to take up more glucose -- a process that increases the metabolic fuel available for cellular function. One of those growth factors, called granulocyte-macrophage colony-stimulating factor, or GM-CSF was purified in Dr. Golde's laboratory in 1984 and is being used in the treatment of cancer patients to help boost their immune systems following bone marrow transplantation.

Building on this discovery, Dr. Golde identified a portion of the GM-CSF receptor on the cell's surface that stimulates the immune cell to take in glucose. This discovery just happened to coincide with earlier research in his laboratory led b
'"/>

Contact: Kelli Stauning
staunink@mskcc.org
212-639-3573
Memorial Sloan-Kettering Cancer Center
25-Mar-1998


Page: 1 2 3

Related biology news :

1. Growth hormone and IBD: Reduction of intestinal inflammation, promotion of growth
2. Growth study of wild chimpanzees challenges assumptions about early humans
3. Growth hormone activates gene involved in healing damaged tissue
4. Growth factor shows promise in Parkinsons patients
5. Growth hormone could make farm fish bigger, faster to market
6. Growth hormone may stimulate production of T cells to boost bodys ability to fight HIV
7. Growth hormone may boost production of disease-fighting cells in elderly
8. Growth factor receptor signaling critical to intestinal tumor development, studies show
9. Growth factor may determine who grows new blood vessels that protect against heart attacks
10. Growth hormone involved in diabetic kidney disease, study finds
11. Report: High Carbon Dioxide Boosts Duke Forest Growth By 25 Percent

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/31/2016)... 31, 2016  Genomics firm Nabsys has completed a ... Barrett Bready , M.D., who returned to the company ... technical leadership team, including Chief Technology Officer, John ... Steve Nurnberg and Vice President of Software and Informatics, ... Dr. Bready served as CEO of Nabsys ...
(Date:3/23/2016)... , March 23, 2016 ... Interesse erhöhter Sicherheit Gesichts- und Stimmerkennung mit ... Inc. (NASDAQ: MESG ), ein ... dass das Unternehmen mit SpeechPro zusammenarbeitet, um ... der Finanzdienstleistungsbranche, wird die Möglichkeit angeboten, im ...
(Date:3/22/2016)... , PROVO and ... Newborn Screening Ontario (NSO), which operates the highest sample ... molecular testing, and Tute Genomics and UNIConnect, leaders in ... respectively, today announced the launch of a project to ... (NGS) testing panel. NSO has been ...
Breaking Biology News(10 mins):
(Date:5/25/2016)... ... May 25, 2016 , ... Lady had been battling ... her cruciate ligament in her left knee. Lady’s owner Hannah sought the help of ... board-certified veterinary surgeon, to repair her cruciate ligament and help with the pain of ...
(Date:5/24/2016)... May 24, 2016   MedyMatch Technology Ltd ., the ... intelligence, real-time decision support tools in the emergency room, announced ... 2016 Israeli Advanced Technology Industries (IATI) BioMed Conference. ... 15th National Life Sciences and Technology Week, and ... Intercontinental Hotel in Tel Aviv, Israel . ...
(Date:5/23/2016)... ... ... need for blood donations in South Texas and across the nation is growing. , But ... blood donations are on the decline. In fact, donations across the country are at their ... Texas in the last four years alone. , There is no substitute for blood. , ...
(Date:5/23/2016)... -- Oxitec CEO Hadyn Parry will ... ET before the United States House Committee on Science, Space ... in controlling the spread of the Aedes aegypti ...      (Logo: http://photos.prnewswire.com/prnh/20150630/227348 ) Oxitec has ... Trials in Brazil , Panama ...
Breaking Biology Technology:
Cached News: