HOME >> BIOLOGY >> NEWS
HIV-1 Levels In Semen Don't Correspond To Viral Levels In Blood, Say Pitt,,Researchers In A Report At 12th World AIDS Conference

PITTSBURGH, Penn., June 25--Current testing practices, which typically measure the viral load or the amount of freely circulating genetic material of HIV-1 in the blood, may not accurately detect the amount of virus in semen, say researchers from the University of Pittsburgh Graduate School of Public Health (GSPH).

In a report presented on June 30 at the 12th World AIDS Conference, Pitt researcher, Phalguni Gupta, Ph.D., emphasized that testing viral load levels in semen as well as targeting treatments to sites of seminal virus production may offer physicians a better way to monitor viral activity in HIV-infected patients and also stem transmission of HIV-1.

"To accurately assess how easily and how much HIV can be transmitted during risky sexual contact with HIV-infected individuals, we can't rely on blood tests. Instead, we need to test viral load levels in semen," said Dr. Gupta, who is a professor of infectious diseases and microbiology at Pitt's GSPH.

"Most of the HIV-infected men in our study had very high levels of virus present in their semen at certain time points and then at other times had a lower amount. This indicates that some men may be more likely to transmit the virus during risky sexual behaviors at certain times."

Dr. Gupta and his colleagues are the first to report HIV in semen can fluctuate greatly in some HIV-infected men and does not correspond to viral levels in blood. A previous study by the Pitt group found differences between the types of HIV found in the blood and semen of some HIV-infected men.

"These results, taken together with our new findings, indicate that virus found in the semen originates from a separate site, different from that of virus that circulates throughout the body." remarked Dr. Gupta. "If we locate the site where seminal virus is produced, we may be able to target treatments to this site and suppress replication of viral strains which may be different than
'"/>

Contact: Amy Kemp
kempam@a1.isd.upmc.edu
412-624-2607
University of Pittsburgh Medical Center
30-Jun-1998


Page: 1 2 3

Related biology news :

1. Scientists discover proteins involved in spread of HIV-1 infection
2. Dana-Farber scientists discover natural blocker of HIV-1 virus
3. Kissing RNA and HIV-1: Unraveling the details
4. Can a universal HIV-1 vaccine be developed? AIDScience.com describes current research strategies
5. Human genome bears a virus related to HIV-1
6. Wistar immunologists awarded grants to promote the development of vaccinesagainst HIV-1 and human papilloma viruses
7. NIAID-Supported Scientists Discover Origin Of HIV-1
8. Major New Study Shows HIV-1 Antibodies Found In Urine
9. Boosting Immune Response Against HIV-1 Key To Controlling Infection, Say University Of Pittsburgh Researchers
10. The Reason The French Have Low Levels Of Heart Disease
11. Marine Life In South Pacific Region Found To Be Impervious To Oceans Highest Arsenic Levels

Post Your Comments:
(Date:12/22/2014)... Dec. 22, 2014 Research and Markets ... the "The Global Watermarking and Fingerprinting Markets" ... http://photos.prnewswire.com/prnh/20130307/600769 This insight ... watermarking and fingerprinting markets. Watermarking aims to control ...
(Date:12/19/2014)... 18, 2014   LaunchKey , the first decentralized mobile ... Internet of Things era, today announced the close of ... was led by Metamorphic Ventures with participation from ENIAC ... and others.  LaunchKey has raised $4 million to date, ...
(Date:12/17/2014)... Dec. 16, 2014 Research and Markets ( ... "Global Chemical Sensor Market 2015-2019" report to their ... One major trend upcoming in this market is ... Chemical sensors help in recording of patient data for ...
Breaking Biology News(10 mins):The Global Watermarking and Fingerprinting Markets 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2
(Date:1/22/2015)... Bedford, NH (PRWEB) January 22, 2015 ... offers a table top laboratory homogenizer, the PandaPLUS 2000, ... nanoparticles, nanodispersions, nanoemulsions , and cell disruption . ... processing dairy products, fruit juices, liquid food, food additives ...
(Date:1/22/2015)... January 22, 2015 Protocol Networks brings ... growing team of brand-neutral, independent consultants, Protocol Networks has ... explained that over the years, his company has attracted ... Town of Plainfield, as well as others. With the ...
(Date:1/22/2015)... Dr. Greg Leyer of UAS Labs recently was ... Pre-Conference seminar on probiotics in San Diego, CA. , ... conference for health care professionals. This year’s pre-conference seminar was ... in health. Dr. Leyer spoke about the emerging topics and ...
(Date:1/22/2015)... Jersey , 22 de enero de 2015  El Dr. ... hoy su llamada a nominaciones para 2015. Este prestigioso ... hecho, o tiene el potencial para hacer, contribuciones destacadas ... se aceptarán hasta el 15 de marzo de 2015 ...
Breaking Biology Technology:GEA Niro Soavi Announces the PandaPLUS 2000 Homogenizer for Processing New Applications for Nanoemulsions and Cell Disruption 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4
Cached News: