HOME >> BIOLOGY >> NEWS
Harbor Branch Oceanographic Institution And Novartis Pharma AG Sign AgreementFor Licensing And Development Of Anti-Cancer Compound, Discodermolide

FT. PIERCE, FL- Harbor Branch Oceanographic Institution, Inc., Fort Pierce, Florida, has entered into an agreement to license its marine-derived, anti-cancer agent, discodermolide, to Novartis Pharma AG, Basle, Switzerland, on an exclusive world-wide basis.

Discodermolide is an anti-cancer compound derived from the marine sponge, Discodermia dissoluta, first collected in 1987 by Dr. Shirley A. Pomponi, Director of Harbor Branch's Division of Biomedical Marine Research. The compound was isolated from the sponge and characterized by Dr. Sarath P. Gunasekera and Dr. Ross E. Longley at Harbor Branch in 1990. Subsequent studies by the Harbor Branch team and collaborators revealed the compound to be a potent, anti-tumor agent that is effective in killing human cancer cells in vitro with a mechanism of action similar to that of the clinical anti-cancer agent Taxol .

Under terms of the license agreement, Harbor Branch grants Novartis exclusive, world-wide rights for the development, use, manufacture and sale of discodermolide for all potential therapeutic indications. Novartis will provide Harbor Branch with funding for continued research on discodermolide, as well as future payments based on developmental milestones and royalties from the sale of the compound as a drug for the treatment of cancer.

J. Seward Johnson, Jr., of Princeton, N.J., Chairman of Harbor Branch, states: "This agreement is the result of over 14 years of drug discovery research at Harbor Branch, and is the culmination of the last 8 years of research on discodermolide by the Harbor Branch team. Given the exciting and promising pre-clinical data on discodermolide and the expertise in drug development which Novartis provides, our hope is that discodermolide will eventually surpass other chemotherapeutic agents as an effective treatment for cancer".

Harbor Branch Oceanographic Institution, Inc. is one of the nation's premi
'"/>

Contact: Shirley A. Pomponi, Ph.D.
dbmr@hboi.edu
(561) 465-2400 X449
Harbor Branch Oceanographic Institution
16-Apr-1998


Page: 1 2

Related biology news :

1. Academy Harbor Consortium releases letter on mercury to President Bush
2. Microorganisms are cleaning up Boston Harbor, UMass study finds
3. 2002 Cold Spring Harbor Laboratory Meetings
4. Harbor Branch scientist aids in Mexico manatee rescue effort
5. Harbor Branch scientists to study predation habits of jellyfish-like animals in Gulf Of Maine
6. Harbor Branch to receive $2.1 million of a $4.9 million multi-institutional grant to discover new natural product leads for cancer chemotherapy
7. Harbor Branch Scientists Discover Bioluminescent Octopus
8. Harbor Branch Web Developers Team With ABC News To Bring Ocean Adventure To A Computer Near You
9. Harbor Branch Web Developers Bring Adventures @Sea To Every Desktop
10. Harbor Branch Oceanographic Trains Displaced Fishermen And Women In New Careers As Aquafarmers
11. Harbor Branch Oceanographic Institutions Aquaculture Division Studies Viability Of Controlled Reproduction Of Southern Flounder In Captivity

Post Your Comments:
(Date:4/27/2015)... Apr. 27, 2015 NXT-ID, Inc. (NASDAQ: ... company focused on the growing mobile commerce market, announces ... pre-order customers the first week of May, 2015 and ... of May. Gino Pereira , ... for the company as Wocket® enters the consumer market. ...
(Date:4/21/2015)... High crime rate, increasing ... access control systems market in Saudi Arabia ... published report by TechSci Research " Saudi Arabia Access Control ... systems market in Saudi Arabia ... control systems market in the Kingdom is growing at ...
(Date:4/20/2015)... 20, 2015 The announcement comes ... Glenbeigh Records Management (GRM), Ireland,s foremost ... Bank. Having built up an impressive track record of clients ... player within the records management sector in Dubai ... is GCC staffbase and employ a further eight staff members ...
Breaking Biology News(10 mins):Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 3Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 2Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 3Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 2Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 3
(Date:5/21/2015)... of Prussia, PA (PRWEB) May 21, 2015 ... Julia O’Neill has joined the firm as senior statistician ... than 30 years of experience in the management and ... vaccines, biologics, pharmaceutical and chemical industries. , “We’re delighted ... our longstanding capabilities in data analytics,” said Dr. Philippe ...
(Date:5/20/2015)... Pa. , May 20, 2015  Select ... that the Federal Trade Commission granted early termination ... Antitrust Improvements Act of 1976, as amended, applicable ... MJ Acquisition Corporation, a joint venture that Select ... L.P. As previously announced, MJ Acquisition ...
(Date:5/20/2015)... 2015  Haemonetics Corporation (NYSE: HAE ) announced ... will present at The Jefferies 2015 Global Healthcare Conference ... 1 st , 2015 at 8:30am Eastern time.  ... live via webcast at: http://wsw.com/webcast/jeff88/hae ... ) is a global healthcare company dedicated to providing ...
(Date:5/20/2015)... Mulhouse, France, Cambridge, MA (PRWEB) May 20, 2015 ... of high quality transporter assay services for Drug-Drug ... Pharmacology, and Rhenovia Pharma, a world leader in ... using Translational Quantitative Systems Pharmacology supported by biosimulation, ... agreement. , The agreement allows both companies to ...
Breaking Biology Technology:Julia O’Neill Joins Tunnell Consulting’s Operational and Process Improvement Practice 2Select Medical Corporation's Proposed Acquisition of Concentra Inc. through Joint Venture with Welsh Carson Receives Antitrust Clearance 2Optivia Biotechnology Inc. and Rhenovia Pharma Sign Partnership Agreement 2Optivia Biotechnology Inc. and Rhenovia Pharma Sign Partnership Agreement 3
Cached News: