HOME >> BIOLOGY >> NEWS
Harbor Branch Oceanographic Institution And Novartis Pharma AG Sign AgreementFor Licensing And Development Of Anti-Cancer Compound, Discodermolide

FT. PIERCE, FL- Harbor Branch Oceanographic Institution, Inc., Fort Pierce, Florida, has entered into an agreement to license its marine-derived, anti-cancer agent, discodermolide, to Novartis Pharma AG, Basle, Switzerland, on an exclusive world-wide basis.

Discodermolide is an anti-cancer compound derived from the marine sponge, Discodermia dissoluta, first collected in 1987 by Dr. Shirley A. Pomponi, Director of Harbor Branch's Division of Biomedical Marine Research. The compound was isolated from the sponge and characterized by Dr. Sarath P. Gunasekera and Dr. Ross E. Longley at Harbor Branch in 1990. Subsequent studies by the Harbor Branch team and collaborators revealed the compound to be a potent, anti-tumor agent that is effective in killing human cancer cells in vitro with a mechanism of action similar to that of the clinical anti-cancer agent Taxol .

Under terms of the license agreement, Harbor Branch grants Novartis exclusive, world-wide rights for the development, use, manufacture and sale of discodermolide for all potential therapeutic indications. Novartis will provide Harbor Branch with funding for continued research on discodermolide, as well as future payments based on developmental milestones and royalties from the sale of the compound as a drug for the treatment of cancer.

J. Seward Johnson, Jr., of Princeton, N.J., Chairman of Harbor Branch, states: "This agreement is the result of over 14 years of drug discovery research at Harbor Branch, and is the culmination of the last 8 years of research on discodermolide by the Harbor Branch team. Given the exciting and promising pre-clinical data on discodermolide and the expertise in drug development which Novartis provides, our hope is that discodermolide will eventually surpass other chemotherapeutic agents as an effective treatment for cancer".

Harbor Branch Oceanographic Institution, Inc. is one of the nation's premi
'"/>

Contact: Shirley A. Pomponi, Ph.D.
dbmr@hboi.edu
(561) 465-2400 X449
Harbor Branch Oceanographic Institution
16-Apr-1998


Page: 1 2

Related biology news :

1. Academy Harbor Consortium releases letter on mercury to President Bush
2. Microorganisms are cleaning up Boston Harbor, UMass study finds
3. 2002 Cold Spring Harbor Laboratory Meetings
4. Harbor Branch scientist aids in Mexico manatee rescue effort
5. Harbor Branch scientists to study predation habits of jellyfish-like animals in Gulf Of Maine
6. Harbor Branch to receive $2.1 million of a $4.9 million multi-institutional grant to discover new natural product leads for cancer chemotherapy
7. Harbor Branch Scientists Discover Bioluminescent Octopus
8. Harbor Branch Web Developers Team With ABC News To Bring Ocean Adventure To A Computer Near You
9. Harbor Branch Web Developers Bring Adventures @Sea To Every Desktop
10. Harbor Branch Oceanographic Trains Displaced Fishermen And Women In New Careers As Aquafarmers
11. Harbor Branch Oceanographic Institutions Aquaculture Division Studies Viability Of Controlled Reproduction Of Southern Flounder In Captivity

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/31/2016)... 31, 2016   ... the "Company") LegacyXChange is excited to release ... soon to be launched online site for trading 100% ... ) will also provide potential shareholders a sense of ... to an industry that is notorious for fraud. The ...
(Date:3/22/2016)... 22, 2016 According ... Market for Consumer Industry by Type (Image, Motion, ... (Communication & IT, Entertainment, Home Appliances, & ... to 2022", published by MarketsandMarkets, the market ... reach USD 26.76 Billion by 2022, at ...
(Date:3/17/2016)... 17, 2016 ABI Research, the leader ... global biometrics market will reach more than $30 ... from 2015. Consumer electronics, particularly smartphones, continue to ... anticipated to reach two billion shipments by 2021 ... Pavlakis , Research Analyst at ABI Research. "Surveillance ...
Breaking Biology News(10 mins):
(Date:4/29/2016)... 29, 2016 According to ... Research "Separation Systems for Commercial Biotechnology Market - ... Forecast 2015 - 2023", the separation systems for ... Mn in 2014 and is projected to expand ... 2023 to reach US$ 19,227.8 Mn in 2023. ...
(Date:4/29/2016)... ... April 29, 2016 , ... Intelligent Implant Systems announced today that ... 510(k) for sale in the United States. These components expand the capabilities of ... With one-level sales beginning in October of 2015, the company has seen significant sales ...
(Date:4/28/2016)... , April 28, 2016 ... company reports the Company,s CEO  was featured in ... Accelerators Enter When VCs Fear To Tread: ... Leader magazine is an essential business ... everything from emerging biotechs to Big Pharmas. Their ...
(Date:4/28/2016)... York, NY (PRWEB) , ... April 28, 2016 ... ... QuickSTAT has made significant investments in recruiting top industry experts, and expanding its ... Platform, which provides industry-leading tools for clients to manage their clinical trial projects. ...
Breaking Biology Technology:
Cached News: