Heart failure patients with worst heart function are good candidates for pacemakers

The pacemaker has taken on an increasingly important role in recent years. Originally used to fix electrical abnormalities in people with irregular heart rhythms, it is now in favor for heart failure patients as a way to "resynchronize" a weak and struggling heart.

In a study of 22 patients, Johns Hopkins researchers have found that those whose hearts have the largest amount of timing discord, and whose hearts are often weakest, are the ones that seem to benefit most from a pacemaker. Pacing therapy improved the heart's ability to contract and pump out blood by an average of 35 percent.

Study results were published in a recent issue of Circulation, an American Heart Association journal.

"The problem we set out to solve was determining which heart failure patients would respond best to pacemakers," says David A. Kass, M.D., lead author of the study and professor of medicine and biomedical engineering at Hopkins. "The devices are expensive and permanent, and the patients are so sick we can't afford to waste time."

In normal hearts, cells in the right upper chamber, or atrium, emit an electrical impulse that travels through the heart on a specified route through a small group of cells called the A-V node and along a track that divides into the right and left lower chambers, or ventricles. As the impulse travels down the right and left branches at the same speed, the muscle contracts, or beats, in a coordinated (nearly simultaneous) manner.

In some heart failure patients, however, there is a block in one branch, causing marked delay in contraction to a portion of the heart as the electrical impulse must now reach this region by a slow detour through the heart muscle itself. As a result, the heart "wobbles" and must struggle to send blood out to the body.

Kass' team likens the failing heart to an automobile engine. If the engine pistons aren't timed correctly, the car will still move but will have worse fuel econ

Contact: Karen Infeld
Johns Hopkins Medical Institutions

Page: 1 2

Related biology news :

1. Heart gene yields insights into evolution, disease risk
2. Heartless worms hold clues to cardiac arrhythmias, sudden death
3. Media invited to attend International Society For Heart & Lung Transplantation meeting April 21-24
4. Heart and lung transplantation clinical trial results to be announced at ISHLT meeting
5. Heart may heal with help from oxygen-sensitive genes, new study suggests
6. Heart drug might help fight chronic fungal infections
7. Heart disease among some Japanese may be due to sequencing variation inside a gene
8. Heart size and function uncoupled by researchers
9. Heart disease gene linked to prostate cancer
10. Heart-felt stress can be more dangerous to immune system
11. Society for Womens Health Research will be releasing reports related to Heart Month

Post Your Comments:

(Date:2/5/2020)... ... 2020 , ... Crystal Diagnostics (CDx) announced today that the ... to proprietary liquid crystal technology for rapid and accurate detection of foodborne pathogens. ... December 3, 2019. Together, these patents protect the company’s liquid crystal technology currently ...
(Date:1/30/2020)... (PRWEB) , ... January 30, 2020 , ... Accelera ... an eye on the Canadian market, is pleased to announce that the company has ... growth since the company launched in 2017. , “We are so thrilled to ...
(Date:1/29/2020)... ... January 29, 2020 , ... ... it will start production of a DNA vaccine against the novel coronavirus (2019-nCoV) ... Pharmaceuticals. A grant of up to $9 million from the Coalition for Epidemic ...
Breaking Biology News(10 mins):
(Date:2/3/2020)... ... February 03, 2020 , ... ... Firm Travel, Law Firm Travel, Technology Industry Travel and Biotech/Healthcare Industry Travel Indexes. ... Each Index illustrates the following statistics:, Average airfare ...
(Date:1/28/2020)... ... January 28, 2020 , ... Today, Salimetrics ... . The new Salivary Total Human IgG Assay Kit exemplifies Salimetrics’ ... in saliva, researchers can extend the accuracy and ease of use of salivary ...
(Date:1/24/2020)... ... January 24, 2020 , ... The impact of new medicines, ... laboratory and clinical services during the first two decades of the 21st century ... Slone Partners celebrates its 20th anniversary this year, its evolution as ...
(Date:1/22/2020)... ... January 21, 2020 , ... ... Taylor as Southern Midwest Region Industrial and Institutional (I&I) Account Manager. Darrell will ... , Darrell brings over 30 years of sales experience working across ...
Breaking Biology Technology:
Cached News: