HOME >> BIOLOGY >> NEWS
Hebrew University, German and British researchers develop means to help stress sufferers

Try as we may to suppress memories of highly stressful experiences, they nevertheless come back to bother us even causing attacks of intense fear or other undesirable behavioral impairments.

Now, a group of German, Israeli and British scientists and students have found that a gene-based approach offers promise for development of a treatment that can suppress these reactions, while not impairing memory itself.

In an article appearing as the cover story in the current issue of Molecular Psychiatry, a team of researchers from the Silberman Institute of Life Sciences at the Hebrew University of Jerusalem and the Max Planck Institute for Experimental Medicine in Goettingen, Germany, describe their work with mice who were subjected to stressful conditions.

The team discovered that this stress induces a change in the expression of the acetylcholinesterase gene. Under normal circumstances, this gene produces a vital protein that adheres to neuronal synapses (the interaction sites through which nerve cells communicate with each other). Following stress, however, the same gene produces large quantities of a protein with modified properties that results in heightened electrical signals in the nerve cells communicating through these synapses. The effect is to create reactions of extreme fright or immobilizing shock.

Later encounter with a context which arouses those stressful memories which might be an object, a sound, an image or other form of association -- can set off that same neuronal reaction. Often, this reaction can have serious consequences, such as chronic fatigue or personality disorders, including post- traumatic stress disorder (PTSD). In the U.S., it is estimated that more than 15 million people a year are identified with PTSD or other anxiety disorders.

The research team at the Hebrew University and in Germany and Britain has succeeded in developing an "antisense" agent that acts to neutralize the process whereby the modified pro
'"/>

Contact: Jerry Barach
jerryb@savion.huji.ac.il
972-2-588-2904
The Hebrew University of Jerusalem
11-Dec-2003


Page: 1 2

Related biology news :

1. Case for IBD combination therapy comes from research at Baylor, MIT and Hebrew University
2. Defensive action by influenza viruses demonstrated by Hebrew university researcher
3. Earliest evidence of hereditary genetic disorder discovered by Hebrew University researchers
4. Scientists in Germany and Hebrew University illuminate process in control of flowering in plants
5. Hebrew University young researcher award goes to Dr. Nayef Jarrous
6. Hebrew University Ph.D. graduate wins young scientist prize in US
7. Hebrew University researcher studies reorganization of brain in blind people
8. Hebrew University researchers develop method to improve neutraceutical absorption
9. Faster method for growing adult stem cells for bone regeneration developed at Hebrew University
10. Hebrew University researcher wins prize for work leading to new anti-cancer drugs
11. Hebrew University excavations strengthen dating of archaeological findings to David, Solomon

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/14/2019)... ... 13, 2019 , ... BioMedGPS is excited to host its ... event at Gothenburg’s Universeum Aquarium. Guests will be treated to an aquarium tour, ... Care. , SmartTRAK’s Advanced Wound Care Experts will serve as panelists. Susan Paquette ...
(Date:5/8/2019)... FRANCISCO (PRWEB) , ... May 08, 2019 , ... ... (CRO) – has successfully leveraged the support services provided by Medrio , ... execute a clinical trial sponsor agreement. , By collaborating to position high-quality ...
(Date:5/2/2019)... ... April 30, 2019 , ... ... is pleased to announce that Gunes Bender, Ph.D., a registered patent agent, ... practice group. In his new role, Bender provides technical support and scientific expertise ...
Breaking Biology News(10 mins):
(Date:4/16/2019)... ... 2019 , ... Fulcrum Biometrics , a leading provider ... Pacific (BSP), the largest regionally owned bank in the South Pacific, selected Fulcrum ... deliver a fingerprint-based Know Your Customer (KYC) banking solution that is being rolled ...
(Date:4/10/2019)... Md. (PRWEB) , ... April ... ... GenCure, both regenerative medicine manufacturing technology leaders, have locked into multiple agreements ... ever before. Companies across the regenerative medicine industry, ranging from synthetic biology ...
(Date:4/9/2019)... ... ... Sonny Bar Lisa, or Sonny for short, is a quarter horse that was ... of diagnostics, an MRI was performed which revealed Sonny had torn his left front ... VetStem Regenerative Cell Therapy may be a treatment option for her horse ...
(Date:4/8/2019)... FRANCISCO (PRWEB) , ... April 08, 2019 , ... ... accredited investors a $15 million preferred equity investment in the privately held pharmaceutical company, ... Its leading drug, Lorexys, is targeted at female hypoactive sexual dysfunction disorder and is ...
Breaking Biology Technology:
Cached News: