HOME >> BIOLOGY >> NEWS
High Blood Pressure Caused By Salt Retention May Be Related To Oncogenes Implicated In Cancer

SAN FRANCISCO--Sodium transport - the kidney function that regulates the level of salt in the kidney and bloodstream and, ultimately, blood pressure, may be intimately related to some of the same oncogenes that have been implicated in the unchecked cellular growth of cancer. Douglas Eaton, Ph.D., associate professor of physiology and pediatrics at Emory University and director of Emory's Center for Cell and Molecular Signaling, presents the findings at the Experimental Biology '98 Meeting in San Francisco on Monday.

Dr. Eaton and his colleagues examined genetic, hormonal and pharmacologic changes that affect the sodium channels, which are special protein molecules found in a type of kidney cell. Sodium channels act as a gatekeeper by retaining salt in the kidney or by allowing it to enter the bloodstream in response to changes in blood pressure. Small alterations in these molecules cause them to retain too much salt, which can lead to high blood pressure. About 30 percent of people who have hypertension, or high blood pressure, are reacting to the buildup of too much sodium.

"If the sodium channels are too active," says Dr. Eaton, "then people retain sodium, causing water buildup and an abnormal rise in blood pressure."

Hypertension affects an estimated 62 million Americans and is an underlying cause of heart attacks, heart failure and strokes, as well as kidney failure. Some people have a specific, genetic abnormality that affects the sodium channels, but in other people there is nothing obviously wrong.

"In this other group of people, the sodium channels are switched on or off incorrectly by another molecule," says Dr. Eaton.

The steroid hormone aldosterone regulates how much sodium is released or retained by the sodium channels. In turn, steroid hormones like aldosterone work by switching on and off
'"/>

Contact: Sarah Goodwin
sgoodwi@emory.edu
404-727-3366
Emory University Health Sciences Center
20-Apr-1998


Page: 1 2

Related biology news :

1. Blood pressure hormone may inhibit growth of lung cancer
2. Blood tests identify patients on dialysis at high risk for death from cardiovascular disease
3. Blood banking systems improving in China, more progress needed
4. Blood proteins tied to inflammation
5. Bloodworms way with copper likely provides paradigm for new materials
6. Blood markers may reflect newborns potential of contracting HIV
7. Blood stem cells carry targeted genes
8. Blood vessels trigger development of the pancreas
9. Blood vessels found to signal chain of destruction in bone diseases
10. Blood markers associated with autism and mental retardation
11. Blood test for diagnosing schizophrenia

Post Your Comments:
(Date:7/2/2015)... Sweden , July 2, 2015 ... sensors FPC1025, FPC1035, FPC1145 and FPC1155 from the distributor World ... one of FPC,s distributors in Asia . ... 2015. The sensors will be used by smartphone manufacturers in ... MSEK is included in the communicated revenue guidance of approximately ...
(Date:6/30/2015)... Pa. , June 30, 2015 ... the company as CEO to help further develop Genisphere,s ... wealth of partnering experience, having spent much of the ... including Therakine, Amgen, Baxter Bioscience, and Johnson & Johnson. ... focus on Technology and Biotech Corporate Finance. He graduated ...
(Date:6/26/2015)... -- ATL Technology, LLC, a top provider of electromechanical contract ... solutions, headquartered in Springville, Utah , has ... corporation with locations in Santa Clara, ... ). This acquisition will incorporate MedConx,s manufacturing ... Technology,s existing facility in Costa Rica , ...
Breaking Biology News(10 mins):FPC Receives Order for Touch Fingerprint Sensors of 268 MSEK 2Genisphere Appoints New CEO, Thomas Bliss 2Genisphere Appoints New CEO, Thomas Bliss 3ATL Technology Announces Acquisition of MedConx, Inc. and Expanded Global Footprint 2
(Date:8/3/2015)... (PRWEB) , ... August 03, 2015 , ... ... of benzene. Benzene is processed to get such derivatives as ethylbenzene, a precursor ... are principally used within the automotive industry for the production of tyres and ...
(Date:8/3/2015)... , ... August 03, 2015 , ... Nine field days ... Illinois and Indiana. Hosted by the Soil Health Partnership , the field days ... environmental benefits while potentially increasing farm productivity and income. , Brent Bible has practiced ...
(Date:8/3/2015)... E-QURE Corp. (OTCQB: EQUR), a ... Signal Therapy device ("BST Device"), a new and novel ... chronic wounds, today announced that the Company has signed ... specializing in medical devices, for the marketing and distribution ... 70 years old, sales, marketing and distribution company in ...
(Date:8/3/2015)... 3, 2015 According to a ... Cell Culture: Asia to Witness ... the global 3D cell culture market was valued at US$ 586.1 ... a CAGR of 29.1% to account for US$ 2,717.6 ... TOC:  http://www.persistencemarketresearch.com/market-research/3d-cell-cultures-market.asp 3D cell culture refers ...
Breaking Biology Technology:World Benzene Market to Surpass 46 MMT by 2020, According to TechSci Research Report Published at MarketPublishers.com 2World Benzene Market to Surpass 46 MMT by 2020, According to TechSci Research Report Published at MarketPublishers.com 3Soil Health Field Days Kick Off Throughout Midwest 2Soil Health Field Days Kick Off Throughout Midwest 3E-QURE Corp Signs Second Distribution Agreement in Israel 2E-QURE Corp Signs Second Distribution Agreement in Israel 3Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 2Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 3Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 4
Cached News: