High levels of sex hormones doubles risk for breast cancer in postmenopa...( prevent breast cancer which affects 1...)

prevent breast cancer, which affects 193,700 women in the United States annually. The Endogenous Hormones and Breast Cancer Collaborative Group is international consortium that includes epidemiologists from the United States, England, Italy, and Japan. The group conducts research on the relationship of endogenous hormones to breast cancer development. Each of the nine cohorts in which the association of sex hormones with breast cancer has been prospectively evaluated is represented in this study. For the current analysis, researchers from each of the nine cohorts pooled their data so they could obtain more precise estimates of the risk of developing breast cancer associated with elevated estrogen and androgen levels. The larger sample size achieved by pooling the data also allows for analyses of subsets of interest.

The nine cohorts and the principal investigators who make up the Endogenous Hormones and Breast Cancer Collaborative Group include: the Columbia, MO. cohort (JF Dorgan), the Guernsey, UK cohort (TJ Key); Nurses' Health Study cohort (SE Hankinson), New York University Women's Health Study cohort (PG Toniolo), the ORDET, Italy cohort (F Berrino), the Rancho Bernardo cohort (E Barrett-Connor), the RERF, Japan cohort (M Kabuto), the SOF cohort (JA Cauley), and the Washington County, MD cohort (KJ Helzlsouer). Fox Chase Cancer Center, one of the nations first comprehensive cancer centers designated by the National Cancer Institute in 1974, conducts basic and clinical research; programs of prevention, detection and treatment of cancer; and community outreach. For more information about Fox Chase activities, visit the Centers web site at http://www.fccc.edu or call 1-888-FOX CHASE.

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Contact: Karen Carter Mallet
K_Carter@fccc.edu
215-728-2700
Fox Chase Cancer Center
16-Apr-2002

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